Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SORD
  • Mouse genes Sord
  • Rat genes Sord
  • Zfish genes sord
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sord

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047833	D-sorbitol dehydrogenase (acceptor) activity	Sord	IDA		Mouse	PMID:6626150
Molecular Function	GO:0047833	D-sorbitol dehydrogenase (acceptor) activity	Sord	IMP	MGI:MGI:3616090	Mouse	PMID:9403062
Molecular Function	GO:0047833	D-sorbitol dehydrogenase (acceptor) activity	Sord	IMP	MGI:MGI:3616090	Mouse	PMID:9604875
Molecular Function	GO:0046526	D-xylulose reductase activity	Sord	IDA		Mouse	PMID:38160
Molecular Function	GO:0042802	identical protein binding	SORD	IPI	UniProtKB:Q00796	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	SORD	IPI	UniProtKB:Q00796	Human	PMID:21516116
Molecular Function	GO:0042802	identical protein binding	SORD	IPI	UniProtKB:Q00796	Human	PMID:31515488
Molecular Function	GO:0042802	identical protein binding	SORD	IPI	UniProtKB:Q00796	Human	PMID:32296183
Molecular Function	GO:0042802	identical protein binding	Sord	IDA		Rat	PMID:11306057|RGD:1601367
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	SORD	IMP		Human	PMID:32367058
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	SORD	IDA		Human	PMID:3365415
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	SORD	IDA		Human	PMID:6870831
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	SORD	IDA		Human	PMID:8487505
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	Sord	IMP	MGI:MGI:3616090	Mouse	PMID:9604875
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	Sord	IDA		Mouse	PMID:6626150
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	Sord	IMP	MGI:MGI:3616090	Mouse	PMID:9403062
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	Sord	IDA		Mouse	PMID:1914521
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	Sord	IDA		Mouse	PMID:7171128
Molecular Function	GO:0003939	L-iditol 2-dehydrogenase activity	Sord	IDA		Mouse	PMID:722274
Molecular Function	GO:0051287	NAD binding	SORD	IDA		Human	PMID:12962626
Molecular Function	GO:0008270	zinc ion binding	SORD	IDA		Human	PMID:12962626
Molecular Function	GO:0008270	zinc ion binding	Sord	IDA		Rat	PMID:11306057|RGD:1601367
Cellular Component	GO:0005829	cytosol	Sord	IDA		Mouse	PMID:6626150
Cellular Component	GO:0005829	cytosol	Sord	IDA		Mouse	PMID:38160
Cellular Component	GO:0005829	cytosol	Sord	IDA		Mouse	PMID:11882650
Cellular Component	GO:0070062	extracellular exosome	SORD	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	SORD	IDA		Human	PMID:21557262
Cellular Component	GO:0070062	extracellular exosome	SORD	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	SORD	IDA		Human	PMID:8487505
Cellular Component	GO:0005739	mitochondrion	Sord	IDA		Mouse	MGI:MGI:3836088|PMID:18799757
Cellular Component	GO:0031514	motile cilium	Sord	IDA		Mouse	MGI:MGI:3836088|PMID:18799757
Biological Process	GO:0030317	flagellated sperm motility	Sord	IDA		Mouse	MGI:MGI:3836088|PMID:18799757
Biological Process	GO:0046370	fructose biosynthetic process	SORD	IDA		Human	PMID:3365415
Biological Process	GO:0046370	fructose biosynthetic process	SORD	IDA		Human	PMID:6870831
Biological Process	GO:0046370	fructose biosynthetic process	SORD	IDA		Human	PMID:8487505
Biological Process	GO:0046370	fructose biosynthetic process	Sord	IMP	MGI:MGI:3616090	Mouse	PMID:9604875
Biological Process	GO:0046370	fructose biosynthetic process	Sord	IDA		Mouse	PMID:18799757
Biological Process	GO:0019640	glucuronate catabolic process to xylulose 5-phosphate	Sord	IDA		Mouse	PMID:38160
Biological Process	GO:0051160	L-xylitol catabolic process	SORD	IDA		Human	PMID:8487505
Biological Process	GO:0051164	L-xylitol metabolic process	SORD	IDA		Human	PMID:3365415
Biological Process	GO:0046686	response to cadmium ion	Sord	IDA		Rat	PMID:10620479|RGD:1601368
Biological Process	GO:0046688	response to copper ion	Sord	IDA		Rat	PMID:11044632|RGD:1599065
Biological Process	GO:0009725	response to hormone	Sord	IDA		Rat	PMID:9838221|RGD:1601370
Biological Process	GO:0031667	response to nutrient levels	Sord	IEP		Rat	PMID:16740392|RGD:1601361
Biological Process	GO:0006970	response to osmotic stress	Sord	IEP		Rat	PMID:14551351|RGD:1601363
Biological Process	GO:0009410	response to xenobiotic stimulus	Sord	IEP		Rat	PMID:15064821|RGD:1601360
Biological Process	GO:0006062	sorbitol catabolic process	SORD	IDA		Human	PMID:12962626
Biological Process	GO:0006062	sorbitol catabolic process	SORD	IMP		Human	PMID:32367058
Biological Process	GO:0006062	sorbitol catabolic process	SORD	IDA		Human	PMID:3365415
Biological Process	GO:0006062	sorbitol catabolic process	SORD	IDA		Human	PMID:6870831
Biological Process	GO:0006062	sorbitol catabolic process	SORD	IDA		Human	PMID:8487505
Biological Process	GO:0006060	sorbitol metabolic process	Sord	IDA		Mouse	PMID:722274
Biological Process	GO:0006060	sorbitol metabolic process	Sord	IDA		Mouse	PMID:6626150

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern