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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Sox10

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sox10
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003682chromatin bindingSox10IDAMousePMID:15729346
Molecular FunctionGO:0003682chromatin bindingSox10IDARatPMID:27466180|RGD:12879825
Molecular FunctionGO:0003677DNA bindingSox10IDAMouseMGI:MGI:5544144|PMID:24204311
Molecular FunctionGO:0003677DNA bindingSox10IDAMouseMGI:MGI:5805298|PMID:27532821
Molecular FunctionGO:0003677DNA bindingSox10IDARatPMID:9412504|RGD:70017
Molecular FunctionGO:0001216DNA-binding transcription activator activitySox10IDARatPMID:26525805|RGD:11251833
Molecular FunctionGO:0003700DNA-binding transcription factor activitySox10IDAMouseMGI:MGI:5544144|PMID:24204311
Molecular FunctionGO:0003700DNA-binding transcription factor activitySox10IDAMouseMGI:MGI:5805298|PMID:27532821
Molecular FunctionGO:0003700DNA-binding transcription factor activitySox10IMPMGI:MGI:2151173MousePMID:17084361
Molecular FunctionGO:0003700DNA-binding transcription factor activitySox10IDARatPMID:10559384|RGD:12859026
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificSox10IDAMouseMGI:MGI:5049797|PMID:21610032
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificSox10IDAMousePMID:15729346
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIRGD:733723RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIUniProtKB:F1LMV3RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIUniProtKB:O35137RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIUniProtKB:P02831RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIUniProtKB:P05554RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIUniProtKB:P08047RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIUniProtKB:P17325RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIUniProtKB:P31361RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIUniProtKB:P32442RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIUniProtKB:P43120RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIUniProtKB:P51514RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIUniProtKB:P51774RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIUniProtKB:P63015RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIUniProtKB:P70396RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIUniProtKB:Q03172RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIUniProtKB:Q6J1H4RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSox10IPIUniProtKB:Q9EQW6RatPMID:16582099|RGD:6892704
Molecular FunctionGO:0042802identical protein bindingSOX10IPIUniProtKB:P56693HumanPMID:11029584
Molecular FunctionGO:1990841promoter-specific chromatin bindingSox10IMPRatPMID:22037207|RGD:12859028
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:P20265HumanPMID:11029584
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:P23760HumanPMID:11029584
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:Q13287HumanPMID:16214168
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:P63165HumanPMID:16494873
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:P63279HumanPMID:16494873
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:O43186HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:P78424HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:Q15038HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:Q5SWW7HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:Q9ULV5-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:Q9Y5V3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:P17252HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:P61981HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:P62937-2HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:Q15047-2HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:Q8TAP4-4HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingSOX10IPIUniProtKB:Q92993HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingSox10IPIUniProtKB:Q8CFN5MouseMGI:MGI:5049797|PMID:21610032
Molecular FunctionGO:0005515protein bindingSox10IPIPR:Q8BQM9MousePMID:23575864
Molecular FunctionGO:0005515protein bindingSox10IPIPR:Q8BHS6MousePMID:19304657
Molecular FunctionGO:0005515protein bindingSox10IPIPR:A2AGH6MousePMID:23575864
Molecular FunctionGO:0005515protein bindingSox10IPIUniProtKB:Q13287RatPMID:16214168|RGD:8554825
Molecular FunctionGO:0000978RNA polymerase II cis-regulatory region sequence-specific DNA bindingSox10IDAMouseMGI:MGI:5049797|PMID:21610032
Molecular FunctionGO:0000978RNA polymerase II cis-regulatory region sequence-specific DNA bindingSox10IDAMousePMID:15102707
Molecular FunctionGO:1990837sequence-specific double-stranded DNA bindingSOX10IDAHumanPMID:28473536
Molecular FunctionGO:0000976transcription cis-regulatory region bindingSox10IDAMousePMID:17084361
Molecular FunctionGO:0000976transcription cis-regulatory region bindingSox10IDARatPMID:26525805|RGD:11251833
Molecular FunctionGO:0008134transcription factor bindingSox10IGIMGI:MGI:1926212MousePMID:23575864
Molecular FunctionGO:0008134transcription factor bindingSox10IDAMousePMID:19179536
Cellular ComponentGO:0000785chromatinSox10IDARatPMID:27466180|RGD:12879825
Cellular ComponentGO:0005737cytoplasmSox10IDAMousePMID:19304657
Cellular ComponentGO:0005737cytoplasmSox10IDARatPMID:12138193|RGD:1600052
Cellular ComponentGO:0005741mitochondrial outer membraneSox10IDAMousePMID:19304657
Cellular ComponentGO:0005654nucleoplasmSOX10IDAHumanGO_REF:0000052
Cellular ComponentGO:0005634nucleusSOX10IDAHumanPMID:18512230
Cellular ComponentGO:0005634nucleusSox10IDAMouseMGI:MGI:3527299|PMID:15572147
Cellular ComponentGO:0005634nucleusSox10IDAMouseMGI:MGI:3531619|PMID:15713637
Cellular ComponentGO:0005634nucleusSox10IDAMousePMID:19304657
Cellular ComponentGO:0005634nucleusSox10IDAMousePMID:25433207
Cellular ComponentGO:0005634nucleusSox10IDARatPMID:12138193|RGD:1600052
Biological ProcessGO:0030154cell differentiationSox10IMPMGI:MGI:2151173MousePMID:11799060
Biological ProcessGO:0048469cell maturationSox10IMPMGI:MGI:2151173MousePMID:15102707
Biological ProcessGO:0048469cell maturationSox10IGIMGI:MGI:98370MousePMID:15102707
Biological ProcessGO:0071393cellular response to progesterone stimulusSox10IEPRatPMID:17478888|RGD:12859030
Biological ProcessGO:0071466cellular response to xenobiotic stimulusSox10IEPRatPMID:24403178|RGD:12879828
Biological ProcessGO:0022010central nervous system myelinationSox10IMPMouseMGI:MGI:5544144|PMID:24204311
Biological ProcessGO:0022010central nervous system myelinationSox10IMPMouseMGI:MGI:5805298|PMID:27532821
Biological ProcessGO:1904888cranial skeletal system developmentsox10IGIZFIN:ZDB-MRPHLNO-170208-2,ZFIN:ZDB-MRPHLNO-170208-3ZfishPMID:27418670
Biological ProcessGO:1904888cranial skeletal system developmentsox10IGIZFIN:ZDB-MRPHLNO-051220-4,ZFIN:ZDB-MRPHLNO-170208-2ZfishPMID:27418670
Biological ProcessGO:0048589developmental growthSox10IMPMGI:MGI:3701358MousePMID:16790476
Biological ProcessGO:0048066developmental pigmentationsox10IMPZFIN:ZDB-GENO-980202-1190ZfishPMID:9007256
Biological ProcessGO:0048066developmental pigmentationsox10IMPZFIN:ZDB-GENO-980202-1189ZfishPMID:9007256
Biological ProcessGO:0048546digestive tract morphogenesisSox10IMPMGI:MGI:1857401MousePMID:6512238
Biological ProcessGO:0048546digestive tract morphogenesisSox10IMPMGI:MGI:1857401MousePMID:15843399
Biological ProcessGO:0048484enteric nervous system developmentSox10IMPMouseMGI:MGI:3527299|PMID:15572147
Biological ProcessGO:0048484enteric nervous system developmentSox10IMPMGI:MGI:1857401MousePMID:6512238
Biological ProcessGO:0048484enteric nervous system developmentSox10IMPMGI:MGI:3701358MousePMID:16790476
Biological ProcessGO:0048484enteric nervous system developmentsox10IMPZFIN:ZDB-GENO-980202-1190ZfishPMID:15817223
Biological ProcessGO:0048484enteric nervous system developmentsox10IMPZFIN:ZDB-GENO-980202-136ZfishPMID:15817223
Biological ProcessGO:0021782glial cell developmentsox10IMPZFIN:ZDB-CRISPR-191008-22,ZFIN:ZDB-CRISPR-191008-23ZfishPMID:30924555
Biological ProcessGO:0010001glial cell differentiationsox10IGIZFIN:ZDB-MRPHLNO-090825-1,ZFIN:ZDB-MRPHLNO-090825-3ZfishPMID:19570850
Biological ProcessGO:0010001glial cell differentiationsox10IGIZFIN:ZDB-GENO-090826-2,ZFIN:ZDB-MRPHLNO-090825-1ZfishPMID:19570850
Biological ProcessGO:0001701in utero embryonic developmentSox10IGIMGI:MGI:98370MousePMID:16790476
Biological ProcessGO:0048839inner ear developmentsox10IGIZFIN:ZDB-GENO-980202-1565,ZFIN:ZDB-MRPHLNO-070130-7,ZFIN:ZDB-MRPHLNO-090422-9ZfishPMID:19132125
Biological ProcessGO:0048839inner ear developmentsox10IGIZFIN:ZDB-GENO-980202-1565,ZFIN:ZDB-MRPHLNO-070130-7,ZFIN:ZDB-MRPHLNO-090422-7,ZFIN:ZDB-MRPHLNO-090422-8,ZFIN:ZDB-MRPHLNO-090422-9ZfishPMID:19132125
Biological ProcessGO:0048839inner ear developmentsox10IMPZFIN:ZDB-GENO-980202-1565ZfishPMID:19132125
Biological ProcessGO:0048839inner ear developmentsox10IGIZFIN:ZDB-GENO-980202-1565,ZFIN:ZDB-MRPHLNO-090422-7,ZFIN:ZDB-MRPHLNO-090422-8ZfishPMID:19132125
Biological ProcessGO:0050935iridophore differentiationsox10IMPZFIN:ZDB-GENO-980202-1565ZfishPMID:29621239
Biological ProcessGO:0032808lacrimal gland developmentSox10IMPMGI:MGI:4820417MousePMID:24924191
Biological ProcessGO:0030318melanocyte differentiationSox10IMPMGI:MGI:3701358MousePMID:16790476
Biological ProcessGO:0030318melanocyte differentiationsox10IMPZFIN:ZDB-GENO-980202-1565ZfishPMID:29621239
Biological ProcessGO:0030318melanocyte differentiationsox10IGIZFIN:ZDB-GENE-011207-1,ZFIN:ZDB-GENO-121004-5ZfishPMID:22562198
Biological ProcessGO:0061138morphogenesis of a branching epitheliumSox10IGIMGI:MGI:98371MousePMID:24924191
Biological ProcessGO:0061138morphogenesis of a branching epitheliumSox10IMPMGI:MGI:4820417MousePMID:24924191
Biological ProcessGO:0022011myelination in peripheral nervous systemsox10IGIZFIN:ZDB-MRPHLNO-051220-4,ZFIN:ZDB-MRPHLNO-170208-2,ZFIN:ZDB-MRPHLNO-170208-3ZfishPMID:27418670
Biological ProcessGO:0022011myelination in peripheral nervous systemsox10IGIZFIN:ZDB-MRPHLNO-170208-2,ZFIN:ZDB-MRPHLNO-170208-3ZfishPMID:27418670
Biological ProcessGO:0043066negative regulation of apoptotic processSox10IMPMouseMGI:MGI:3527299|PMID:15572147
Biological ProcessGO:0090090negative regulation of canonical Wnt signaling pathwaySox10IDAMouseMGI:MGI:3768575|PMID:17875931
Biological ProcessGO:0045892negative regulation of DNA-templated transcriptionSox10IDARatPMID:16582099|RGD:6892704
Biological ProcessGO:0050768negative regulation of neurogenesissox10IMPZFIN:ZDB-GENO-980202-291ZfishPMID:15677337
Biological ProcessGO:0010626negative regulation of Schwann cell proliferationSox10IMPRatPMID:25536222|RGD:12879826
Biological ProcessGO:0014032neural crest cell developmentsox10IMPZFIN:ZDB-GENO-980202-1565ZfishPMID:10631172
Biological ProcessGO:0014032neural crest cell developmentsox10IMPZFIN:ZDB-GENO-980202-136ZfishPMID:11684650
Biological ProcessGO:0001755neural crest cell migrationSox10IMPMouseMGI:MGI:3527299|PMID:15572147
Biological ProcessGO:0001755neural crest cell migrationsox10IMPZFIN:ZDB-GENO-980202-1190ZfishPMID:15817223
Biological ProcessGO:0001755neural crest cell migrationsox10IMPZFIN:ZDB-GENO-980202-136ZfishPMID:15817223
Biological ProcessGO:0007405neuroblast proliferationSox10IMPMousePMID:16857183
Biological ProcessGO:0021772olfactory bulb developmentsox10IMPZfishPMID:23539289|ZFIN:ZDB-PUB-130410-34
Biological ProcessGO:0014003oligodendrocyte developmentSox10IMPMouseMGI:MGI:5805298|PMID:27532821
Biological ProcessGO:0014003oligodendrocyte developmentSox10IMPMouseMGI:MGI:5544144|PMID:24204311
Biological ProcessGO:0048709oligodendrocyte differentiationSox10IMPMouseMGI:MGI:5544144|PMID:24204311
Biological ProcessGO:0048709oligodendrocyte differentiationSox10IMPMouseMGI:MGI:5805298|PMID:27532821
Biological ProcessGO:0048709oligodendrocyte differentiationSox10IMPMGI:MGI:3701358MousePMID:16790476
Biological ProcessGO:0048709oligodendrocyte differentiationSox10IMPMGI:MGI:2151173MousePMID:17084361
Biological ProcessGO:0048709oligodendrocyte differentiationsox10IMPZFIN:ZDB-GENO-070131-8ZfishPMID:17065232
Biological ProcessGO:0071600otic vesicle morphogenesissox10IMPZfishPMID:9007247
Biological ProcessGO:0048840otolith developmentsox10IMPZFIN:ZDB-GENO-980202-1565ZfishPMID:19132125
Biological ProcessGO:0007422peripheral nervous system developmentSox10IGIMGI:MGI:98370MousePMID:16790476
Biological ProcessGO:0050931pigment cell differentiationsox10IMPZFIN:ZDB-GENO-980202-1189ZfishPMID:9007256
Biological ProcessGO:0050931pigment cell differentiationsox10IMPZFIN:ZDB-GENO-980202-1190ZfishPMID:9007256
Biological ProcessGO:0043473pigmentationsox10IMPZFIN:ZDB-MRPHLNO-170208-3ZfishPMID:27418670
Biological ProcessGO:0043473pigmentationsox10IMPZFIN:ZDB-MRPHLNO-051220-4ZfishPMID:27418670
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionSox10IDAMouseMGI:MGI:5544144|PMID:24204311
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionSox10IDAMouseMGI:MGI:5805298|PMID:27532821
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionSox10IDAMouseMGI:MGI:5049797|PMID:21610032
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionSox10IMPMGI:MGI:2151173MousePMID:17084361
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionSox10IDARatPMID:16582099|RGD:6892704
Biological ProcessGO:0010628positive regulation of gene expressionSox10IMPRatPMID:10559384|RGD:12859026
Biological ProcessGO:0010628positive regulation of gene expressionsox10IGIZFIN:ZDB-GENE-990910-11ZfishPMID:19527705
Biological ProcessGO:0014015positive regulation of gliogenesisSox10IMPMouseMGI:MGI:3527299|PMID:15572147
Biological ProcessGO:0031643positive regulation of myelinationSox10IMPRatPMID:25536222|RGD:12879826
Biological ProcessGO:0002052positive regulation of neuroblast proliferationSox10IMPMousePMID:16857183
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IISox10IDAMousePMID:19304657
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IISox10IGIMGI:MGI:1920431MousePMID:19179536
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IISox10IGIMGI:MGI:1918953MousePMID:19304657
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IISox10IMPMousePMID:16857183
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IISox10IGIMGI:MGI:104554MousePMID:15729346
Biological ProcessGO:0006355regulation of DNA-templated transcriptionSox10IDARatPMID:9412504|RGD:70017
Biological ProcessGO:0060041retina development in camera-type eyesox10IMPZFIN:ZDB-CRISPR-191008-22,ZFIN:ZDB-CRISPR-191008-23ZfishPMID:30924555
Biological ProcessGO:0014044Schwann cell developmentsox10IMPZFIN:ZDB-GENO-110803-1ZfishPMID:19955371
Biological ProcessGO:0014044Schwann cell developmentsox10IMPZFIN:ZDB-GENO-080402-2ZfishPMID:18176560
Biological ProcessGO:0014044Schwann cell developmentsox10IMPZFIN:ZDB-GENO-080430-1ZfishPMID:18176560
Biological ProcessGO:0014037Schwann cell differentiationsox10IMPZFIN:ZDB-GENO-070131-8ZfishPMID:17065232
Biological ProcessGO:0048752semicircular canal morphogenesissox10IMPZFIN:ZDB-GENO-980202-1565ZfishPMID:19132125
Biological ProcessGO:0048863stem cell differentiationSox10IEPRatPMID:12691661|RGD:1600051
Biological ProcessGO:0006366transcription by RNA polymerase IISox10IMPMousePMID:16857183
Biological ProcessGO:0006368transcription elongation by RNA polymerase IISox10IDARatPMID:25524031|RGD:12879827
Biological ProcessGO:0050936xanthophore differentiationsox10IMPZFIN:ZDB-GENO-980202-1565ZfishPMID:29621239

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory