Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SOX11
  • Mouse genes Sox11
  • Rat genes Sox11
  • Zfish genes sox11a,sox11b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sox11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Sox11	IDA		Mouse	MGI:MGI:5285167|PMID:19808959
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Sox11	IDA		Mouse	MGI:MGI:5285123|PMID:21527504
Molecular Function	GO:0003677	DNA binding	Sox11	IDA		Mouse	MGI:MGI:5009531|PMID:18403418
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Sox11	IDA		Mouse	MGI:MGI:3803393|PMID:18505825
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Sox11	IDA		Rat	PMID:12637543|RGD:8554307
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Sox11	IDA		Mouse	MGI:MGI:5285123|PMID:21527504
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Sox11	IDA		Rat	PMID:16115881|RGD:1581111
Molecular Function	GO:0005515	protein binding	Sox11	IPI	UniProtKB:P56222	Rat	PMID:12637543|RGD:8554307
Molecular Function	GO:0005515	protein binding	Sox11	IPI	UniProtKB:Q6MG27	Rat	PMID:12637543|RGD:8554307
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SOX11	IDA		Human	PMID:19808959
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SOX11	IDA		Human	PMID:21124928
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Sox11	IDA		Mouse	MGI:MGI:3803393|PMID:18505825
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Sox11	IDA		Rat	PMID:12637543|RGD:8554307
Cellular Component	GO:0005654	nucleoplasm	SOX11	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SOX11	IDA		Human	PMID:17934069
Cellular Component	GO:0005634	nucleus	Sox11	IDA		Mouse	MGI:MGI:3836136|PMID:15456859
Cellular Component	GO:0005634	nucleus	Sox11	IDA		Mouse	MGI:MGI:5285123|PMID:21527504
Cellular Component	GO:0005634	nucleus	Sox11	IDA		Mouse	MGI:MGI:5285172|PMID:19490090
Cellular Component	GO:0005634	nucleus	Sox11	IDA		Rat	PMID:12637543|RGD:8554307
Cellular Component	GO:0005886	plasma membrane	SOX11	IDA		Human	GO_REF:0000052
Biological Process	GO:0007420	brain development	sox11a	IMP	ZFIN:ZDB-MRPHLNO-150820-2	Zfish	PMID:24886874
Biological Process	GO:0007420	brain development	sox11b	IMP	ZFIN:ZDB-MRPHLNO-110113-1	Zfish	PMID:24886874
Biological Process	GO:0048593	camera-type eye morphogenesis	sox11a	IGI	ZFIN:ZDB-MRPHLNO-080208-4,ZFIN:ZDB-MRPHLNO-141007-5	Zfish	PMID:25010521
Biological Process	GO:0048593	camera-type eye morphogenesis	sox11b	IGI	ZFIN:ZDB-MRPHLNO-080208-4,ZFIN:ZDB-MRPHLNO-141007-5	Zfish	PMID:25010521
Biological Process	GO:0003211	cardiac ventricle formation	Sox11	IMP		Mouse	MGI:MGI:5285157|PMID:20596238
Biological Process	GO:0008283	cell population proliferation	Sox11	IEP		Rat	PMID:15647457|RGD:1581112
Biological Process	GO:0061386	closure of optic fissure	Sox11	IMP		Mouse	MGI:MGI:3797299|PMID:18423449
Biological Process	GO:0061386	closure of optic fissure	sox11a	IGI	ZFIN:ZDB-GENE-030131-8290,ZFIN:ZDB-GENE-040426-1274,ZFIN:ZDB-GENE-980526-466	Zfish	PMID:25557621
Biological Process	GO:0061386	closure of optic fissure	sox11b	IGI	ZFIN:ZDB-GENE-030131-8290,ZFIN:ZDB-GENE-040426-1274,ZFIN:ZDB-GENE-980526-395	Zfish	PMID:25557621
Biological Process	GO:0061303	cornea development in camera-type eye	Sox11	IMP		Mouse	MGI:MGI:3797299|PMID:18423449
Biological Process	GO:0009953	dorsal/ventral pattern formation	sox11b	IDA		Zfish	PMID:22522081
Biological Process	GO:0048557	embryonic digestive tract morphogenesis	Sox11	IMP		Mouse	MGI:MGI:3052265|PMID:15254231
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Sox11	IMP		Mouse	MGI:MGI:3052265|PMID:15254231
Biological Process	GO:0061029	eyelid development in camera-type eye	Sox11	IMP		Mouse	MGI:MGI:3052265|PMID:15254231
Biological Process	GO:0021782	glial cell development	Sox11	IMP		Mouse	MGI:MGI:4838379|PMID:20646169
Biological Process	GO:0021782	glial cell development	Sox11	IMP		Mouse	MGI:MGI:4437361|PMID:20147379
Biological Process	GO:0014009	glial cell proliferation	Sox11	IMP		Mouse	MGI:MGI:4437361|PMID:20147379
Biological Process	GO:0060022	hard palate development	Sox11	IMP		Mouse	MGI:MGI:3052265|PMID:15254231
Biological Process	GO:0001822	kidney development	Sox11	IEP		Rat	PMID:10862152|RGD:1581114
Biological Process	GO:0002088	lens development in camera-type eye	sox11a	IGI	ZFIN:ZDB-GENE-980526-466	Zfish	PMID:25557621
Biological Process	GO:0002088	lens development in camera-type eye	sox11b	IGI	ZFIN:ZDB-GENE-980526-395	Zfish	PMID:25557621
Biological Process	GO:0002089	lens morphogenesis in camera-type eye	Sox11	IMP		Mouse	MGI:MGI:3797299|PMID:18423449
Biological Process	GO:0060174	limb bud formation	Sox11	IMP		Mouse	MGI:MGI:5285157|PMID:20596238
Biological Process	GO:0060425	lung morphogenesis	Sox11	IMP		Mouse	MGI:MGI:3052265|PMID:15254231
Biological Process	GO:0060548	negative regulation of cell death	Sox11	IMP		Mouse	MGI:MGI:5285157|PMID:20596238
Biological Process	GO:0060548	negative regulation of cell death	Sox11	IMP		Mouse	MGI:MGI:4838379|PMID:20646169
Biological Process	GO:0010629	negative regulation of gene expression	SOX11	IMP		Human	PMID:19808959
Biological Process	GO:0010629	negative regulation of gene expression	Sox11	IMP		Mouse	MGI:MGI:5285167|PMID:19808959
Biological Process	GO:0060253	negative regulation of glial cell proliferation	SOX11	IMP		Human	PMID:19808959
Biological Process	GO:0060253	negative regulation of glial cell proliferation	Sox11	IMP		Mouse	MGI:MGI:5285167|PMID:19808959
Biological Process	GO:0050672	negative regulation of lymphocyte proliferation	SOX11	IMP		Human	PMID:20624318
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	sox11a	IGI	ZFIN:ZDB-MRPHLNO-080208-4,ZFIN:ZDB-MRPHLNO-141007-5	Zfish	PMID:25010521
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	sox11b	IGI	ZFIN:ZDB-MRPHLNO-080208-4,ZFIN:ZDB-MRPHLNO-141007-5	Zfish	PMID:25010521
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SOX11	IDA		Human	PMID:19808959
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Sox11	IDA		Mouse	MGI:MGI:5285167|PMID:19808959
Biological Process	GO:2000678	negative regulation of transcription regulatory region DNA binding	Sox11	IMP		Rat	PMID:12637543|RGD:8554307
Biological Process	GO:0014032	neural crest cell development	Sox11	IMP		Mouse	MGI:MGI:5285157|PMID:20596238
Biological Process	GO:0001841	neural tube formation	Sox11	IMP		Mouse	MGI:MGI:5285157|PMID:20596238
Biological Process	GO:0060563	neuroepithelial cell differentiation	Sox11	IMP		Mouse	MGI:MGI:4838379|PMID:20646169
Biological Process	GO:0030182	neuron differentiation	SOX11	IEP		Human	PMID:10574465
Biological Process	GO:0030182	neuron differentiation	sox11b	IMP	ZFIN:ZDB-MRPHLNO-110113-1	Zfish	PMID:20951776
Biological Process	GO:0003357	noradrenergic neuron differentiation	Sox11	IMP		Mouse	MGI:MGI:4437361|PMID:20147379
Biological Process	GO:0003357	noradrenergic neuron differentiation	Sox11	IMP		Rat	PMID:20147379|RGD:8553957
Biological Process	GO:0014003	oligodendrocyte development	Sox11	IEP		Rat	PMID:9632656|RGD:68859
Biological Process	GO:0003151	outflow tract morphogenesis	Sox11	IMP		Mouse	MGI:MGI:3052265|PMID:15254231
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	Sox11	IMP		Mouse	MGI:MGI:3797299|PMID:18423449
Biological Process	GO:0008284	positive regulation of cell population proliferation	Sox11	IMP		Mouse	MGI:MGI:5285157|PMID:20596238
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Sox11	IDA		Mouse	MGI:MGI:5285123|PMID:21527504
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Sox11	IMP		Mouse	MGI:MGI:4437361|PMID:20147379
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Sox11	IMP		Mouse	MGI:MGI:3797299|PMID:18423449
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Sox11	IMP		Mouse	MGI:MGI:5285157|PMID:20596238
Biological Process	GO:0010628	positive regulation of gene expression	SOX11	IMP		Human	PMID:19808959
Biological Process	GO:0010628	positive regulation of gene expression	Sox11	IMP		Mouse	MGI:MGI:5285167|PMID:19808959
Biological Process	GO:0035332	positive regulation of hippo signaling	Sox11	IMP		Mouse	MGI:MGI:5285157|PMID:20596238
Biological Process	GO:0046887	positive regulation of hormone secretion	Sox11	IMP		Mouse	MGI:MGI:5285123|PMID:21527504
Biological Process	GO:2001111	positive regulation of lens epithelial cell proliferation	Sox11	IMP		Mouse	MGI:MGI:3797299|PMID:18423449
Biological Process	GO:0050769	positive regulation of neurogenesis	Sox11	IDA		Mouse	MGI:MGI:5285172|PMID:19490090
Biological Process	GO:0045666	positive regulation of neuron differentiation	SOX11	IMP		Human	PMID:19808959
Biological Process	GO:0045666	positive regulation of neuron differentiation	Sox11	IDA		Mouse	MGI:MGI:5285172|PMID:19490090
Biological Process	GO:0045666	positive regulation of neuron differentiation	Sox11	IMP		Mouse	MGI:MGI:5285167|PMID:19808959
Biological Process	GO:0045778	positive regulation of ossification	SOX11	IMP		Human	PMID:20626275
Biological Process	GO:0045778	positive regulation of ossification	Sox11	IMP		Mouse	MGI:MGI:3052265|PMID:15254231
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	SOX11	IMP		Human	PMID:20626275
Biological Process	GO:2000648	positive regulation of stem cell proliferation	SOX11	IMP		Human	PMID:20626275
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	SOX11	IDA		Human	PMID:21124928
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox11	IDA		Mouse	MGI:MGI:5009531|PMID:18403418
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox11	IDA		Mouse	MGI:MGI:3803393|PMID:18505825
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox11	IMP		Rat	PMID:9632656|RGD:68859
Biological Process	GO:1903670	regulation of sprouting angiogenesis	sox11b	IMP	ZFIN:ZDB-MRPHLNO-080208-4	Zfish	PMID:23456338
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	SOX11	IEP		Human	PMID:20624318
Biological Process	GO:0009611	response to wounding	sox11b	IMP	ZFIN:ZDB-MRPHLNO-110113-1	Zfish	PMID:20951776
Biological Process	GO:0046548	retinal rod cell development	sox11a	IGI	ZFIN:ZDB-MRPHLNO-080208-4,ZFIN:ZDB-MRPHLNO-141007-5	Zfish	PMID:25010521
Biological Process	GO:0046548	retinal rod cell development	sox11b	IGI	ZFIN:ZDB-MRPHLNO-080208-4,ZFIN:ZDB-MRPHLNO-141007-5	Zfish	PMID:25010521
Biological Process	GO:0035914	skeletal muscle cell differentiation	Sox11	IMP		Mouse	PMID:20847309
Biological Process	GO:0001501	skeletal system development	Sox11	IMP		Mouse	MGI:MGI:5285157|PMID:20596238
Biological Process	GO:0060023	soft palate development	Sox11	IMP		Mouse	MGI:MGI:3052265|PMID:15254231
Biological Process	GO:0061053	somite development	Sox11	IMP		Mouse	MGI:MGI:5285157|PMID:20596238
Biological Process	GO:0021510	spinal cord development	Sox11	IMP		Mouse	MGI:MGI:4838379|PMID:20646169
Biological Process	GO:0048485	sympathetic nervous system development	Sox11	IMP		Mouse	MGI:MGI:4437361|PMID:20147379
Biological Process	GO:0060412	ventricular septum morphogenesis	Sox11	IMP		Mouse	MGI:MGI:3052265|PMID:15254231

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern