Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SOX15
  • Mouse genes Sox15
  • Rat genes
  • Zfish genes sox19a,sox19b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sox15

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Sox15	IDA		Mouse	PMID:15863505
Molecular Function	GO:0003677	DNA binding	Sox15	IDA		Mouse	PMID:10821863
Molecular Function	GO:0003700	DNA-binding transcription factor activity	sox19b	IDA		Zfish	PMID:16408288
Molecular Function	GO:0003700	DNA-binding transcription factor activity	sox19a	IDA		Zfish	PMID:16408288
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Sox15	IDA		Mouse	PMID:22344693
Molecular Function	GO:0005515	protein binding	SOX15	IPI	UniProtKB:O14503	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX15	IPI	UniProtKB:Q96LI6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Sox15	IPI	UniProtKB:Q9R059	Mouse	MGI:MGI:3714565|PMID:17363903
Molecular Function	GO:0005515	protein binding	Sox15	IPI	PR:Q64279	Mouse	PMID:16759287
Molecular Function	GO:0005515	protein binding	Sox15	IPI	PR:P20263	Mouse	PMID:15863505
Molecular Function	GO:0005515	protein binding	Sox15	IPI	PR:P20263	Mouse	PMID:22344693
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Sox15	IGI	MGI:MGI:101893	Mouse	PMID:15863505
Cellular Component	GO:0005737	cytoplasm	Sox15	IDA		Mouse	PMID:12915303
Cellular Component	GO:0005634	nucleus	Sox15	IDA		Mouse	PMID:10821863
Cellular Component	GO:0005634	nucleus	Sox15	IDA		Mouse	PMID:15863505
Cellular Component	GO:0005634	nucleus	Sox15	IDA		Mouse	PMID:15367664
Cellular Component	GO:0005667	transcription regulator complex	Sox15	IDA		Mouse	PMID:22344693
Biological Process	GO:0030154	cell differentiation	Sox15	IGI	MGI:MGI:103577	Mouse	PMID:16759287
Biological Process	GO:0006338	chromatin remodeling	sox19b	IMP	ZFIN:ZDB-GENO-221020-7	Zfish	PMID:31940339
Biological Process	GO:0009950	dorsal/ventral axis specification	sox19b	IMP	ZFIN:ZDB-MRPHLNO-120221-2	Zfish	PMID:21467072
Biological Process	GO:0009953	dorsal/ventral pattern formation	sox19b	IDA		Zfish	PMID:22522081
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	sox19b	IMP	ZFIN:ZDB-MRPHLNO-120217-1	Zfish	PMID:22209980
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	sox19b	IMP	ZFIN:ZDB-MRPHLNO-120221-1	Zfish	PMID:22209980
Biological Process	GO:0048627	myoblast development	Sox15	IMP	MGI:MGI:3056078	Mouse	PMID:15367664
Biological Process	GO:0045843	negative regulation of striated muscle tissue development	Sox15	IDA		Mouse	PMID:10821863
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Sox15	IMP		Mouse	MGI:MGI:3714565|PMID:17363903
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Sox15	IDA		Mouse	PMID:10821863
Biological Process	GO:0014033	neural crest cell differentiation	sox19b	IMP	ZFIN:ZDB-FISH-210215-6	Zfish	PMID:31842983
Biological Process	GO:0014033	neural crest cell differentiation	sox19b	IMP	ZFIN:ZDB-FISH-210215-7	Zfish	PMID:31842983
Biological Process	GO:0021915	neural tube development	sox19b	IMP	ZFIN:ZDB-FISH-210215-7	Zfish	PMID:31842983
Biological Process	GO:0021915	neural tube development	sox19b	IMP	ZFIN:ZDB-FISH-210215-6	Zfish	PMID:31842983
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	sox19b	IDA		Zfish	PMID:16408288
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	sox19a	IDA		Zfish	PMID:16408288
Biological Process	GO:0070318	positive regulation of G0 to G1 transition	Sox15	IMP		Mouse	MGI:MGI:3714565|PMID:17363903
Biological Process	GO:2000288	positive regulation of myoblast proliferation	Sox15	IMP		Mouse	MGI:MGI:3714565|PMID:17363903
Biological Process	GO:0014718	positive regulation of satellite cell activation involved in skeletal muscle regeneration	Sox15	IMP		Mouse	MGI:MGI:3714565|PMID:17363903
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox15	IMP		Mouse	MGI:MGI:3714565|PMID:17363903
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox15	IGI	MGI:MGI:101893	Mouse	PMID:15863505
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox15	IDA		Mouse	PMID:16759287
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox15	IGI	MGI:MGI:103577	Mouse	PMID:16759287
Biological Process	GO:0043403	skeletal muscle tissue regeneration	Sox15	IMP	MGI:MGI:3056078	Mouse	PMID:15367664
Biological Process	GO:0060707	trophoblast giant cell differentiation	Sox15	IMP		Mouse	MGI:MGI:3625684|PMID:16759287

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern