Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SOX2
  • Mouse genes Sox2
  • Rat genes Sox2
  • Zfish genes sox2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sox2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Sox2	IDA		Mouse	PMID:15988017
Molecular Function	GO:0003682	chromatin binding	sox2	IDA		Zfish	PMID:24643012
Molecular Function	GO:0031490	chromatin DNA binding	Sox2	IDA		Mouse	PMID:24268575
Molecular Function	GO:0003677	DNA binding	SOX2	IDA		Human	PMID:16153702
Molecular Function	GO:0003677	DNA binding	SOX2	IDA		Human	PMID:18285410
Molecular Function	GO:0003677	DNA binding	SOX2	IDA		Human	PMID:18407919
Molecular Function	GO:0003677	DNA binding	SOX2	IDA		Human	PMID:19427902
Molecular Function	GO:0003677	DNA binding	Sox2	IDA		Mouse	PMID:23798425
Molecular Function	GO:0003677	DNA binding	Sox2	IDA		Mouse	PMID:8625802
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Sox2	IDA		Rat	PMID:12637543|RGD:8554307
Molecular Function	GO:0003700	DNA-binding transcription factor activity	SOX2	IDA		Human	PMID:16153702
Molecular Function	GO:0003700	DNA-binding transcription factor activity	SOX2	IDA		Human	PMID:18027866
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Sox2	IDA		Mouse	MGI:MGI:5882869|PMID:23169531
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Sox2	IDA		Mouse	PMID:7628452
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Sox2	IDA		Mouse	PMID:16932809
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Sox2	IDA		Mouse	PMID:9669521
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Sox2	IDA		Mouse	PMID:17097055
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Sox2	IDA		Mouse	PMID:12665572
Molecular Function	GO:0003700	DNA-binding transcription factor activity	sox2	IDA		Zfish	PMID:16408288
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Sox2	IDA		Mouse	PMID:22344693
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Sox2	IPI	UniProtKB:P20263	Mouse	MGI:MGI:4946164|PMID:21076177
Molecular Function	GO:0035198	miRNA binding	SOX2	IDA		Human	PMID:18710938
Molecular Function	GO:0005515	protein binding	SOX2	IPI	UniProtKB:P35222	Human	PMID:18456656
Molecular Function	GO:0005515	protein binding	SOX2	IPI	UniProtKB:Q01860	Human	PMID:19736317
Molecular Function	GO:0005515	protein binding	SOX2	IPI	UniProtKB:Q93009	Human	PMID:23667531
Molecular Function	GO:0005515	protein binding	SOX2	IPI	UniProtKB:O95983	Human	PMID:24048479
Molecular Function	GO:0005515	protein binding	SOX2	IPI	UniProtKB:P41743	Human	PMID:24525231
Molecular Function	GO:0005515	protein binding	SOX2	IPI	UniProtKB:P63165	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX2	IPI	UniProtKB:Q01860	Human	PMID:25702638
Molecular Function	GO:0005515	protein binding	SOX2	IPI	UniProtKB:Q99986	Human	PMID:27334688
Molecular Function	GO:0005515	protein binding	SOX2	IPI	UniProtKB:A8MW92	Human	PMID:29358331
Molecular Function	GO:0005515	protein binding	SOX2	IPI	UniProtKB:Q96JM7	Human	PMID:30442713
Molecular Function	GO:0005515	protein binding	SOX2	IPI	UniProtKB:P63165	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Sox2	IPI	UniProtKB:Q9ER74	Mouse	MGI:MGI:4946171|PMID:21062744
Molecular Function	GO:0005515	protein binding	Sox2	IPI	UniProtKB:Q00899	Mouse	MGI:MGI:3850573|PMID:19536159
Molecular Function	GO:0005515	protein binding	Sox2	IPI	UniProtKB:Q80Z64	Mouse	MGI:MGI:5532893|PMID:23892456
Molecular Function	GO:0005515	protein binding	Sox2	IPI	UniProtKB:Q60520	Mouse	MGI:MGI:3844410|PMID:19139101
Molecular Function	GO:0005515	protein binding	Sox2	IPI	UniProtKB:A2A432|UniProtKB:Q3TCH7|UniProtKB:Q3U1J4|UniProtKB:Q80T85|UniProtKB:Q8BLB7|UniProtKB:Q8CFE3	Mouse	MGI:MGI:7387162|PMID:30442713
Molecular Function	GO:0005515	protein binding	Sox2	IPI	UniProtKB:A2AJK6|UniProtKB:Q6PDQ2	Mouse	MGI:MGI:5437412|PMID:21532573
Molecular Function	GO:0005515	protein binding	Sox2	IPI	UniProtKB:P20263	Mouse	MGI:MGI:5462499|PMID:23108051
Molecular Function	GO:0005515	protein binding	Sox2	IPI	UniProtKB:Q3URR7	Mouse	MGI:MGI:4457231|PMID:19740739
Molecular Function	GO:0005515	protein binding	Sox2	IPI	UniProtKB:Q60793	Mouse	MGI:MGI:4887542|PMID:19816951
Molecular Function	GO:0005515	protein binding	Sox2	IPI	UniProtKB:P20263	Mouse	MGI:MGI:5320277|PMID:20362541
Molecular Function	GO:0005515	protein binding	Sox2	IPI	UniProtKB:Q5BL09	Mouse	MGI:MGI:4946164|PMID:21076177
Molecular Function	GO:0005515	protein binding	Sox2	IPI	UniProtKB:Q62315	Mouse	MGI:MGI:5887185|PMID:26523946
Molecular Function	GO:0005515	protein binding	Sox2	IPI	MGI:MGI:103557	Mouse	PMID:25901318
Molecular Function	GO:0005515	protein binding	Sox2	IPI	PR:P20263	Mouse	PMID:22344693
Molecular Function	GO:0005515	protein binding	Sox2	IPI	PR:P20263	Mouse	PMID:17507372
Molecular Function	GO:0005515	protein binding	Sox2	IPI	PR:P63013	Mouse	PMID:23447615
Molecular Function	GO:0005515	protein binding	Sox2	IPI	PR:P63015	Mouse	PMID:23447615
Molecular Function	GO:0005515	protein binding	Sox2	IPI	PR:Q02248	Mouse	PMID:15781477
Molecular Function	GO:0005515	protein binding	Sox2	IPI	PR:P20263	Mouse	PMID:7590241
Molecular Function	GO:0005515	protein binding	Sox2	IPI	PR:P20263	Mouse	PMID:15863505
Molecular Function	GO:0005515	protein binding	Sox2	IPI	UniProtKB:Q6MG27	Rat	PMID:12637543|RGD:8554307
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Sox2	IGI	MGI:MGI:101893	Mouse	PMID:15863505
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Sox2	IDA		Mouse	PMID:12665572
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Sox2	IDA		Mouse	PMID:15082719
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Sox2	IPI	MGI:MGI:101893	Mouse	PMID:25901318
Molecular Function	GO:0043565	sequence-specific DNA binding	SOX2	IDA		Human	PMID:20713518
Molecular Function	GO:0043565	sequence-specific DNA binding	Sox2	IDA		Mouse	MGI:MGI:5882869|PMID:23169531
Molecular Function	GO:0043565	sequence-specific DNA binding	Sox2	IDA		Mouse	PMID:18400104
Molecular Function	GO:0043565	sequence-specific DNA binding	Sox2	IDA		Mouse	PMID:9649510
Molecular Function	GO:0043565	sequence-specific DNA binding	Sox2	IDA		Mouse	PMID:9669521
Molecular Function	GO:0043565	sequence-specific DNA binding	Sox2	IDA		Mouse	PMID:7628452
Molecular Function	GO:0043565	sequence-specific DNA binding	sox2	IPI	ZFIN:ZDB-GENE-980605-4	Zfish	PMID:23950494
Molecular Function	GO:0043565	sequence-specific DNA binding	sox2	IPI	ZFIN:ZDB-GENE-980526-333	Zfish	PMID:23950494
Molecular Function	GO:0043565	sequence-specific DNA binding	sox2	IPI	ZFIN:ZDB-GENE-030131-5486	Zfish	PMID:23950494
Molecular Function	GO:0043565	sequence-specific DNA binding	sox2	IPI	ZFIN:ZDB-GENE-980526-485	Zfish	PMID:23950494
Molecular Function	GO:0043565	sequence-specific DNA binding	sox2	IPI	ZFIN:ZDB-GENE-010416-1	Zfish	PMID:23950494
Molecular Function	GO:0043565	sequence-specific DNA binding	sox2	IPI	ZFIN:ZDB-GENE-010111-1	Zfish	PMID:23950494
Molecular Function	GO:0043565	sequence-specific DNA binding	sox2	IPI	ZFIN:ZDB-GENE-030909-1	Zfish	PMID:23950494
Molecular Function	GO:0043565	sequence-specific DNA binding	sox2	IPI	ZFIN:ZDB-GENE-980526-102	Zfish	PMID:23950494
Molecular Function	GO:0043565	sequence-specific DNA binding	sox2	IDA		Zfish	PMID:23950494
Molecular Function	GO:0000976	transcription cis-regulatory region binding	SOX2	IDA		Human	PMID:18407919
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Sox2	IDA		Mouse	MGI:MGI:4887547|PMID:19328208
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Sox2	IDA		Mouse	PMID:25901318
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Sox2	IDA		Mouse	PMID:20123909
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Sox2	IDA		Rat	PMID:12637543|RGD:8554307
Cellular Component	GO:0000785	chromatin	Sox2	IDA		Mouse	PMID:23798425
Cellular Component	GO:0005737	cytoplasm	SOX2	IDA		Human	PMID:18027866
Cellular Component	GO:0005737	cytoplasm	Sox2	IDA		Mouse	MGI:MGI:1201714|PMID:9512512
Cellular Component	GO:0005737	cytoplasm	Sox2	IDA		Mouse	PMID:12514105
Cellular Component	GO:0005829	cytosol	SOX2	IDA		Human	PMID:18000303
Cellular Component	GO:0005654	nucleoplasm	SOX2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SOX2	IDA		Human	PMID:17291498
Cellular Component	GO:0005634	nucleus	SOX2	IDA		Human	PMID:18027866
Cellular Component	GO:0005634	nucleus	SOX2	IDA		Human	PMID:18285410
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	MGI:MGI:6416702|PMID:32127020
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	MGI:MGI:5285172|PMID:19490090
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:31481660
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:9512512
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:23284756
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:19796622
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:22992956
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:16932809
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:20531390
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:23056351
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:17522155
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:23447615
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:18448678
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:24191021
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:21300049
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:25535395
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:18287078
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:24036311
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:25335925
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:16631155
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:22232070
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:20123909
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:12514105
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Mouse	PMID:17507372
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Rat	PMID:12637543|RGD:8554307
Cellular Component	GO:0005634	nucleus	Sox2	IDA		Rat	PMID:19161985|RGD:8661678
Cellular Component	GO:0005667	transcription regulator complex	Sox2	IDA		Mouse	PMID:22344693
Cellular Component	GO:0005667	transcription regulator complex	Sox2	IDA		Mouse	PMID:17507372
Biological Process	GO:0021984	adenohypophysis development	Sox2	IMP	MGI:MGI:2449045	Mouse	PMID:16932809
Biological Process	GO:0021984	adenohypophysis development	Sox2	IEP		Rat	PMID:21815952|RGD:8661681
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	Sox2	IMP	MGI:MGI:2135304	Mouse	PMID:9851841
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	Sox2	IMP	MGI:MGI:3589809	Mouse	PMID:17522155
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	Sox2	IMP	MGI:MGI:3625175	Mouse	PMID:17522155
Biological Process	GO:0045165	cell fate commitment	Sox2	IDA		Mouse	PMID:18374910
Biological Process	GO:0001708	cell fate specification	Sox2	IMP	MGI:MGI:2449045	Mouse	PMID:12514105
Biological Process	GO:0008283	cell population proliferation	sox2	IMP	ZFIN:ZDB-MRPHLNO-080329-1	Zfish	PMID:25150399
Biological Process	GO:0008283	cell population proliferation	sox2	IMP	ZFIN:ZDB-MRPHLNO-150324-5	Zfish	PMID:25150399
Biological Process	GO:0071276	cellular response to cadmium ion	Sox2	IDA		Mouse	PMID:15219627
Biological Process	GO:0021987	cerebral cortex development	Sox2	IMP	MGI:MGI:3052123	Mouse	PMID:15240551
Biological Process	GO:0021987	cerebral cortex development	Sox2	IMP	MGI:MGI:2181440	Mouse	PMID:15240551
Biological Process	GO:0050973	detection of mechanical stimulus involved in equilibrioception	Sox2	IMP	MGI:MGI:2447995	Mouse	PMID:15846349
Biological Process	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	Sox2	IMP	MGI:MGI:2447995	Mouse	PMID:15846349
Biological Process	GO:0048852	diencephalon morphogenesis	Sox2	IMP	MGI:MGI:2181440	Mouse	PMID:15240551
Biological Process	GO:0048852	diencephalon morphogenesis	Sox2	IMP	MGI:MGI:3052123	Mouse	PMID:15240551
Biological Process	GO:0048568	embryonic organ development	Sox2	IMP	MGI:MGI:3589809	Mouse	PMID:17522155
Biological Process	GO:0048568	embryonic organ development	Sox2	IMP	MGI:MGI:3625175	Mouse	PMID:17522155
Biological Process	GO:0001714	endodermal cell fate specification	SOX2	IDA		Human	PMID:21245162
Biological Process	GO:0021538	epithalamus development	sox2	IMP	ZFIN:ZDB-MRPHLNO-140611-1	Zfish	PMID:24498133
Biological Process	GO:0060441	epithelial tube branching involved in lung morphogenesis	Sox2	IDA		Mouse	PMID:18374910
Biological Process	GO:0001654	eye development	SOX2	IEP		Human	PMID:18285410
Biological Process	GO:0048592	eye morphogenesis	sox2	IMP	ZFIN:ZDB-MRPHLNO-060922-3	Zfish	PMID:16603149
Biological Process	GO:0048592	eye morphogenesis	sox2	IMP	ZFIN:ZDB-MRPHLNO-060922-4	Zfish	PMID:16603149
Biological Process	GO:0031101	fin regeneration	sox2	IMP	ZFIN:ZDB-MRPHLNO-060922-3	Zfish	PMID:20089153
Biological Process	GO:0030900	forebrain development	SOX2	IEP		Human	PMID:18285410
Biological Process	GO:0021879	forebrain neuron differentiation	Sox2	IMP	MGI:MGI:3052123	Mouse	PMID:15240551
Biological Process	GO:0021879	forebrain neuron differentiation	Sox2	IMP	MGI:MGI:2181440	Mouse	PMID:15240551
Biological Process	GO:0010467	gene expression	Sox2	IMP		Mouse	PMID:26005002
Biological Process	GO:0010467	gene expression	Sox2	IMP		Mouse	PMID:17267691
Biological Process	GO:0048839	inner ear development	SOX2	IEP		Human	PMID:18407919
Biological Process	GO:0042472	inner ear morphogenesis	Sox2	IMP	MGI:MGI:2447995	Mouse	PMID:15846349
Biological Process	GO:0060119	inner ear receptor cell development	sox2	IGI	ZFIN:ZDB-GENO-140225-2	Zfish	PMID:20025865
Biological Process	GO:0060119	inner ear receptor cell development	sox2	IGI	ZFIN:ZDB-GENO-140225-3,ZFIN:ZDB-MRPHLNO-060922-4	Zfish	PMID:20025865
Biological Process	GO:0060119	inner ear receptor cell development	sox2	IMP	ZFIN:ZDB-MRPHLNO-060922-4	Zfish	PMID:20025865
Biological Process	GO:0060235	lens induction in camera-type eye	Sox2	IGI	MGI:MGI:101898	Mouse	PMID:17140559
Biological Process	GO:0048286	lung alveolus development	Sox2	IDA		Mouse	PMID:18374910
Biological Process	GO:0030539	male genitalia development	Sox2	IMP	MGI:MGI:2449045	Mouse	PMID:16932809
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	SOX2	IDA		Human	PMID:18285410
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Sox2	IDA		Mouse	MGI:MGI:3768575|PMID:17875931
Biological Process	GO:1902807	negative regulation of cell cycle G1/S phase transition	SOX2	IDA		Human	PMID:18268498
Biological Process	GO:0045596	negative regulation of cell differentiation	Sox2	IMP		Mouse	PMID:17507372
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	SOX2	IDA		Human	PMID:18268498
Biological Process	GO:0045665	negative regulation of neuron differentiation	Sox2	IDA		Mouse	PMID:16631155
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	Sox2	IDA		Mouse	PMID:15781477
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Sox2	IGI	MGI:MGI:101893	Mouse	PMID:9649510
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	Sox2	IGI	MGI:MGI:88276	Mouse	PMID:15781477
Biological Process	GO:0007405	neuroblast proliferation	Sox2	IMP	MGI:MGI:3625176	Mouse	PMID:16651659
Biological Process	GO:0007405	neuroblast proliferation	Sox2	IMP	MGI:MGI:3052123	Mouse	PMID:15240551
Biological Process	GO:0007405	neuroblast proliferation	Sox2	IMP	MGI:MGI:2181440	Mouse	PMID:15240551
Biological Process	GO:0030182	neuron differentiation	Sox2	IMP	MGI:MGI:3625176	Mouse	PMID:16651659
Biological Process	GO:0030182	neuron differentiation	Sox2	IDA		Mouse	PMID:16631155
Biological Process	GO:0048663	neuron fate commitment	Sox2	IMP	MGI:MGI:3589809	Mouse	PMID:17015430
Biological Process	GO:0097150	neuronal stem cell population maintenance	Sox2	IGI		Mouse	MGI:MGI:5306514|PMID:22198669
Biological Process	GO:0007219	Notch signaling pathway	Sox2	IDA		Mouse	PMID:16631155
Biological Process	GO:0030910	olfactory placode formation	Sox2	IGI	MGI:MGI:101898	Mouse	PMID:17140559
Biological Process	GO:0001649	osteoblast differentiation	SOX2	IDA		Human	PMID:18187129
Biological Process	GO:0001649	osteoblast differentiation	Sox2	IDA		Mouse	PMID:15781477
Biological Process	GO:1905040	otic placode development	sox2	IMP	ZFIN:ZDB-GENO-181105-1	Zfish	PMID:29355522
Biological Process	GO:0071599	otic vesicle development	sox2	IMP	ZFIN:ZDB-GENO-181105-1	Zfish	PMID:29355523
Biological Process	GO:0046148	pigment biosynthetic process	Sox2	IMP	MGI:MGI:2447996	Mouse	PMID:12036291
Biological Process	GO:0021982	pineal gland development	sox2	IMP	ZFIN:ZDB-MRPHLNO-140611-1	Zfish	PMID:24498133
Biological Process	GO:0021983	pituitary gland development	SOX2	IEP		Human	PMID:18285410
Biological Process	GO:0045597	positive regulation of cell differentiation	Sox2	IMP		Rat	PMID:19161985|RGD:8661678
Biological Process	GO:0022409	positive regulation of cell-cell adhesion	Sox2	IMP		Rat	PMID:20869108|RGD:8661684
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	sox2	IDA		Zfish	PMID:16408288
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	SOX2	IDA		Human	PMID:18407919
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	SOX2	IDA		Human	PMID:29253717
Biological Process	GO:0030858	positive regulation of epithelial cell differentiation	Sox2	IDA		Mouse	PMID:18374910
Biological Process	GO:0043410	positive regulation of MAPK cascade	SOX2	IDA		Human	PMID:18187129
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	Sox2	IMP	MGI:MGI:3625176	Mouse	PMID:16651659
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	Sox2	IMP	MGI:MGI:3052123	Mouse	PMID:15240551
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	Sox2	IMP	MGI:MGI:2181440	Mouse	PMID:15240551
Biological Process	GO:0045666	positive regulation of neuron differentiation	Sox2	IMP	MGI:MGI:3625176	Mouse	PMID:16651659
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	Sox2	IDA		Mouse	PMID:16631155
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	SOX2	IDA		Human	PMID:21245162
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	SOX2	IDA		Human	PMID:18027866
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox2	IDA		Mouse	MGI:MGI:6377809|PMID:26691508
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox2	IGI	MGI:MGI:101898	Mouse	PMID:17140559
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox2	IGI	MGI:MGI:101893	Mouse	PMID:7590241
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox2	IMP		Mouse	PMID:15988017
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox2	IGI	MGI:MGI:101893	Mouse	PMID:15863505
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox2	IGI	MGI:MGI:101893	Mouse	PMID:17507372
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox2	IGI	MGI:MGI:101893	Mouse	PMID:17097055
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox2	IDA		Mouse	PMID:7628452
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox2	IDA		Mouse	PMID:17507372
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox2	IDA		Mouse	PMID:16932809
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox2	IDA		Mouse	PMID:17097055
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox2	IDA		Rat	PMID:12637543|RGD:8554307
Biological Process	GO:0031099	regeneration	sox2	IMP	ZFIN:ZDB-MRPHLNO-060922-4	Zfish	PMID:20025865
Biological Process	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	SOX2	IDA		Human	PMID:18268498
Biological Process	GO:0006355	regulation of DNA-templated transcription	SOX2	IDA		Human	PMID:16153702
Biological Process	GO:0006355	regulation of DNA-templated transcription	Sox2	IDA		Mouse	PMID:12665572
Biological Process	GO:0010468	regulation of gene expression	SOX2	IMP		Human	PMID:18388306
Biological Process	GO:1905812	regulation of motor neuron axon guidance	sox2	IMP	ZFIN:ZDB-MRPHLNO-150324-5	Zfish	PMID:32292330
Biological Process	GO:1905812	regulation of motor neuron axon guidance	sox2	IMP	ZFIN:ZDB-GENO-220728-3	Zfish	PMID:32292330
Biological Process	GO:1904520	regulation of myofibroblast cell apoptotic process	Sox2	IMP		Rat	PMID:34321385|RGD:155882552
Biological Process	GO:0050767	regulation of neurogenesis	Sox2	IGI	MGI:MGI:109344	Mouse	PMID:22513373
Biological Process	GO:0050767	regulation of neurogenesis	Sox2	IGI	MGI:MGI:1915344	Mouse	PMID:22513373
Biological Process	GO:0050767	regulation of neurogenesis	Sox2	IGI	MGI:MGI:102780	Mouse	PMID:22513373
Biological Process	GO:0050767	regulation of neurogenesis	Sox2	IGI	MGI:MGI:88192	Mouse	PMID:22513373
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Sox2	IDA		Mouse	PMID:19796622
Biological Process	GO:0070848	response to growth factor	SOX2	IDA		Human	PMID:18187129
Biological Process	GO:0010033	response to organic substance	Sox2	IDA		Mouse	PMID:18400104
Biological Process	GO:0090649	response to oxygen-glucose deprivation	Sox2	IMP		Rat	PMID:34321385|RGD:155882552
Biological Process	GO:0032526	response to retinoic acid	Sox2	IDA		Mouse	PMID:18400104
Biological Process	GO:0009611	response to wounding	SOX2	IEP		Human	PMID:17982423
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	Sox2	IMP	MGI:MGI:3625176	Mouse	PMID:16651659
Biological Process	GO:0007605	sensory perception of sound	Sox2	IMP	MGI:MGI:2447996	Mouse	PMID:12036291
Biological Process	GO:0035019	somatic stem cell population maintenance	SOX2	IMP		Human	PMID:18388306
Biological Process	GO:0035019	somatic stem cell population maintenance	SOX2	IDA		Human	PMID:19409607
Biological Process	GO:0035019	somatic stem cell population maintenance	SOX2	IMP		Human	PMID:19736317
Biological Process	GO:0035019	somatic stem cell population maintenance	Sox2	IMP		Mouse	PMID:16767105
Biological Process	GO:0035019	somatic stem cell population maintenance	Sox2	IMP		Mouse	PMID:20720539
Biological Process	GO:0021522	spinal cord motor neuron differentiation	sox2	IMP	ZFIN:ZDB-MRPHLNO-150324-5	Zfish	PMID:32292330
Biological Process	GO:0021522	spinal cord motor neuron differentiation	sox2	IMP	ZFIN:ZDB-GENO-220728-3	Zfish	PMID:32292330
Biological Process	GO:0048863	stem cell differentiation	Sox2	IDA		Mouse	PMID:20123909
Biological Process	GO:0019827	stem cell population maintenance	Sox2	IMP		Mouse	MGI:MGI:5882869|PMID:23169531
Biological Process	GO:0042246	tissue regeneration	Sox2	IEP		Rat	PMID:19845688|RGD:8661679
Biological Process	GO:0043586	tongue development	Sox2	IMP	MGI:MGI:3589809	Mouse	PMID:17015430
Biological Process	GO:0001829	trophectodermal cell differentiation	Sox2	IMP		Mouse	PMID:17507372
Biological Process	GO:0016055	Wnt signaling pathway	Sox2	IGI	MGI:MGI:88276	Mouse	PMID:15781477

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern