Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SOX30
  • Mouse genes Sox30
  • Rat genes Sox30
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sox30

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	SOX30	IPI	UniProtKB:P35222	Human	PMID:29739711
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Sox30	IMP		Mouse	MGI:MGI:6191912|PMID:29866902
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Sox30	IDA		Mouse	MGI:MGI:6191808|PMID:29848638
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Sox30	IMP		Mouse	MGI:MGI:6296172|PMID:29739711
Molecular Function	GO:0005515	protein binding	SOX30	IPI	UniProtKB:Q8IYR0	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	SOX30	IPI	UniProtKB:O43865	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX30	IPI	UniProtKB:Q01543	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX30	IPI	UniProtKB:Q8IYR0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SOX30	IPI	UniProtKB:Q14192	Human	PMID:32296183
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SOX30	IDA		Human	PMID:10359848
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	SOX30	IDA		Human	PMID:28473536
Cellular Component	GO:0010369	chromocenter	Sox30	IDA		Mouse	MGI:MGI:6191808|PMID:29848638
Cellular Component	GO:0005737	cytoplasm	SOX30	IDA		Human	PMID:29739711
Cellular Component	GO:0005829	cytosol	SOX30	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SOX30	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SOX30	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SOX30	IDA		Human	PMID:29739711
Cellular Component	GO:0005634	nucleus	Sox30	IDA		Mouse	MGI:MGI:6191808|PMID:29848638
Cellular Component	GO:0005634	nucleus	Sox30	IDA		Mouse	MGI:MGI:6191912|PMID:29866902
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Sox30	IMP		Mouse	MGI:MGI:6296172|PMID:29739711
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	SOX30	IMP		Human	PMID:29739711
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox30	IMP		Mouse	MGI:MGI:6191912|PMID:29866902
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sox30	IDA		Mouse	MGI:MGI:6191808|PMID:29848638
Biological Process	GO:0120211	proacrosomal vesicle fusion	Sox30	IMP		Mouse	MGI:MGI:6191912|PMID:29866902
Biological Process	GO:0031960	response to corticosteroid	SOX30	IEP		Human	PMID:18436822
Biological Process	GO:0007286	spermatid development	Sox30	IMP		Mouse	MGI:MGI:6191808|PMID:29848638

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern