Source |
Alliance of Genome Resources |
Category | ID | Classification term | Gene | Evidence | Inferred from | Organism | Reference |
---|---|---|---|---|---|---|---|
Molecular Function | GO:0003677 | DNA binding | Sox4 | IDA | Mouse | MGI:MGI:5009531|PMID:18403418 | |
Molecular Function | GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | SOX4 | IDA | Human | PMID:19147588 | |
Molecular Function | GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | Sox4 | IDA | Mouse | MGI:MGI:3803393|PMID:18505825 | |
Molecular Function | GO:0003700 | DNA-binding transcription factor activity | SOX4 | IDA | Human | PMID:16631117 | |
Molecular Function | GO:0003700 | DNA-binding transcription factor activity | SOX4 | IMP | Human | PMID:20049565 | |
Molecular Function | GO:0003700 | DNA-binding transcription factor activity | SOX4 | IMP | Human | PMID:30661772 | |
Molecular Function | GO:0003700 | DNA-binding transcription factor activity | SOX4 | IDA | Human | PMID:7706298 | |
Molecular Function | GO:0003700 | DNA-binding transcription factor activity | Sox4 | IDA | Mouse | MGI:MGI:5285123|PMID:21527504 | |
Molecular Function | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | Sox4 | IDA | Mouse | PMID:22344693 | |
Molecular Function | GO:0035198 | miRNA binding | Sox4 | IDA | Mouse | PMID:26802803 | |
Molecular Function | GO:0005515 | protein binding | SOX4 | IPI | UniProtKB:P63279 | Human | PMID:16631117 |
Molecular Function | GO:0005515 | protein binding | SOX4 | IPI | UniProtKB:Q9Y2X9 | Human | PMID:19147588 |
Molecular Function | GO:0005515 | protein binding | SOX4 | IPI | UniProtKB:P04637 | Human | PMID:19234109 |
Molecular Function | GO:0005515 | protein binding | SOX4 | IPI | UniProtKB:Q09472 | Human | PMID:19234109 |
Molecular Function | GO:0005515 | protein binding | SOX4 | IPI | UniProtKB:Q92793 | Human | PMID:19234109 |
Molecular Function | GO:0005515 | protein binding | SOX4 | IDA | Human | PMID:26291311 | |
Molecular Function | GO:0005515 | protein binding | Sox4 | IPI | UniProtKB:P15884 | Mouse | MGI:MGI:3768575|PMID:17875931 |
Molecular Function | GO:0005515 | protein binding | Sox4 | IPI | PR:P20263 | Mouse | PMID:22344693 |
Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | SOX4 | IDA | Human | PMID:20049565 | |
Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | Sox4 | IDA | Mouse | MGI:MGI:5285157|PMID:20596238 | |
Molecular Function | GO:1990837 | sequence-specific double-stranded DNA binding | SOX4 | IDA | Human | PMID:28473536 | |
Molecular Function | GO:0000976 | transcription cis-regulatory region binding | Sox4 | IDA | Mouse | MGI:MGI:3803393|PMID:18505825 | |
Cellular Component | GO:0005737 | cytoplasm | SOX4 | IDA | Human | PMID:17875931 | |
Cellular Component | GO:0005737 | cytoplasm | Sox4 | IDA | Mouse | PMID:26802803 | |
Cellular Component | GO:0005739 | mitochondrion | SOX4 | IDA | Human | GO_REF:0000052 | |
Cellular Component | GO:0005654 | nucleoplasm | SOX4 | IDA | Human | GO_REF:0000052 | |
Cellular Component | GO:0005634 | nucleus | SOX4 | IDA | Human | PMID:16631117 | |
Cellular Component | GO:0005634 | nucleus | SOX4 | IDA | Human | PMID:17875931 | |
Cellular Component | GO:0005634 | nucleus | SOX4 | IDA | Human | PMID:19234109 | |
Cellular Component | GO:0005634 | nucleus | Sox4 | IDA | Mouse | MGI:MGI:3768575|PMID:17875931 | |
Cellular Component | GO:0005634 | nucleus | Sox4 | IDA | Mouse | PMID:16306355 | |
Cellular Component | GO:0005634 | nucleus | Sox4 | IDA | Mouse | PMID:15645444 | |
Cellular Component | GO:0005667 | transcription regulator complex | Sox4 | IDA | Mouse | PMID:22344693 | |
Biological Process | GO:0035910 | ascending aorta morphogenesis | Sox4 | IMP | Mouse | MGI:MGI:3603061|PMID:16109771 | |
Biological Process | GO:0003289 | atrial septum primum morphogenesis | Sox4 | IMP | Mouse | MGI:MGI:3603061|PMID:16109771 | |
Biological Process | GO:0003215 | cardiac right ventricle morphogenesis | Sox4 | IMP | Mouse | MGI:MGI:3603061|PMID:16109771 | |
Biological Process | GO:0003211 | cardiac ventricle formation | Sox4 | IMP | Mouse | MGI:MGI:5285157|PMID:20596238 | |
Biological Process | GO:0071333 | cellular response to glucose stimulus | Sox4 | IMP | Mouse | MGI:MGI:3819280|PMID:18477811 | |
Biological Process | GO:0061386 | closure of optic fissure | sox4a | IGI | ZFIN:ZDB-GENE-040426-1274 | Zfish | PMID:25557621 |
Biological Process | GO:0061386 | closure of optic fissure | sox4a | IGI | ZFIN:ZDB-GENE-040426-1274,ZFIN:ZDB-GENE-980526-395,ZFIN:ZDB-GENE-980526-466 | Zfish | PMID:25557621 |
Biological Process | GO:0061386 | closure of optic fissure | sox4b | IGI | ZFIN:ZDB-GENE-030131-8290 | Zfish | PMID:25557621 |
Biological Process | GO:0061386 | closure of optic fissure | sox4b | IGI | ZFIN:ZDB-GENE-030131-8290,ZFIN:ZDB-GENE-980526-395,ZFIN:ZDB-GENE-980526-466 | Zfish | PMID:25557621 |
Biological Process | GO:0031018 | endocrine pancreas development | Sox4 | IMP | MGI:MGI:2182092 | Mouse | PMID:16306355 |
Biological Process | GO:0031018 | endocrine pancreas development | sox4b | IMP | ZFIN:ZDB-MRPHLNO-051013-1 | Zfish | PMID:16055112 |
Biological Process | GO:0010467 | gene expression | Sox4 | IDA | Mouse | PMID:31281513 | |
Biological Process | GO:0021782 | glial cell development | Sox4 | IMP | Mouse | MGI:MGI:4838379|PMID:20646169 | |
Biological Process | GO:0021782 | glial cell development | Sox4 | IMP | Mouse | MGI:MGI:4437361|PMID:20147379 | |
Biological Process | GO:0014009 | glial cell proliferation | Sox4 | IMP | Mouse | MGI:MGI:4437361|PMID:20147379 | |
Biological Process | GO:0042593 | glucose homeostasis | Sox4 | IMP | Mouse | MGI:MGI:3819280|PMID:18477811 | |
Biological Process | GO:0007507 | heart development | Sox4 | IMP | Mouse | MGI:MGI:80229|PMID:8614465 | |
Biological Process | GO:0061484 | hematopoietic stem cell homeostasis | Sox4 | IMP | Mouse | PMID:26880577 | |
Biological Process | GO:0060993 | kidney morphogenesis | Sox4 | IMP | Mouse | MGI:MGI:3603061|PMID:16109771 | |
Biological Process | GO:0060174 | limb bud formation | Sox4 | IMP | Mouse | MGI:MGI:5285157|PMID:20596238 | |
Biological Process | GO:0003183 | mitral valve morphogenesis | Sox4 | IMP | Mouse | MGI:MGI:3603061|PMID:16109771 | |
Biological Process | GO:0060548 | negative regulation of cell death | Sox4 | IMP | Mouse | MGI:MGI:4838379|PMID:20646169 | |
Biological Process | GO:0060548 | negative regulation of cell death | Sox4 | IMP | Mouse | MGI:MGI:5285157|PMID:20596238 | |
Biological Process | GO:0008285 | negative regulation of cell population proliferation | SOX4 | IMP | Human | PMID:19234109 | |
Biological Process | GO:0045662 | negative regulation of myoblast differentiation | SOX4 | IDA | Human | PMID:26291311 | |
Biological Process | GO:0031397 | negative regulation of protein ubiquitination | SOX4 | IMP | Human | PMID:19234109 | |
Biological Process | GO:0045879 | negative regulation of smoothened signaling pathway | sox4a | IGI | ZFIN:ZDB-GENE-040426-1274 | Zfish | PMID:25557621 |
Biological Process | GO:0045879 | negative regulation of smoothened signaling pathway | sox4b | IGI | ZFIN:ZDB-GENE-030131-8290 | Zfish | PMID:25557621 |
Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II | SOX4 | IDA | Human | PMID:26291311 | |
Biological Process | GO:0001841 | neural tube formation | Sox4 | IMP | Mouse | MGI:MGI:5285157|PMID:20596238 | |
Biological Process | GO:0060563 | neuroepithelial cell differentiation | Sox4 | IMP | Mouse | MGI:MGI:4838379|PMID:20646169 | |
Biological Process | GO:0003357 | noradrenergic neuron differentiation | Sox4 | IMP | Mouse | MGI:MGI:4437361|PMID:20147379 | |
Biological Process | GO:0043065 | positive regulation of apoptotic process | SOX4 | IMP | Human | PMID:15522200 | |
Biological Process | GO:0090263 | positive regulation of canonical Wnt signaling pathway | Sox4 | IMP | Mouse | MGI:MGI:3768575|PMID:17875931 | |
Biological Process | GO:0090263 | positive regulation of canonical Wnt signaling pathway | Sox4 | IDA | Mouse | MGI:MGI:3768575|PMID:17875931 | |
Biological Process | GO:0008284 | positive regulation of cell population proliferation | SOX4 | IMP | Human | PMID:17875931 | |
Biological Process | GO:0008284 | positive regulation of cell population proliferation | Sox4 | IMP | Mouse | MGI:MGI:5285157|PMID:20596238 | |
Biological Process | GO:0045893 | positive regulation of DNA-templated transcription | SOX4 | IDA | Human | PMID:16631117 | |
Biological Process | GO:0045893 | positive regulation of DNA-templated transcription | SOX4 | IDA | Human | PMID:19147588 | |
Biological Process | GO:0045893 | positive regulation of DNA-templated transcription | SOX4 | IMP | Human | PMID:19234109 | |
Biological Process | GO:0045893 | positive regulation of DNA-templated transcription | Sox4 | IDA | Mouse | MGI:MGI:5285157|PMID:20596238 | |
Biological Process | GO:0045893 | positive regulation of DNA-templated transcription | Sox4 | IDA | Mouse | MGI:MGI:5285123|PMID:21527504 | |
Biological Process | GO:0045588 | positive regulation of gamma-delta T cell differentiation | Sox4 | IMP | Mouse | MGI:MGI:5486619|PMID:23562159 | |
Biological Process | GO:0032024 | positive regulation of insulin secretion | Sox4 | IMP | Mouse | MGI:MGI:3819280|PMID:18477811 | |
Biological Process | GO:0045663 | positive regulation of myoblast differentiation | SOX4 | IDA | Human | PMID:26291311 | |
Biological Process | GO:0045663 | positive regulation of myoblast differentiation | Sox4 | IDA | Mouse | MGI:MGI:6838711|PMID:26291311 | |
Biological Process | GO:2000761 | positive regulation of N-terminal peptidyl-lysine acetylation | SOX4 | IDA | Human | PMID:19234109 | |
Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II | SOX4 | IDA | Human | PMID:19147588 | |
Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II | SOX4 | IMP | Human | PMID:20049565 | |
Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II | SOX4 | IDA | Human | PMID:26291311 | |
Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II | Sox4 | IDA | Mouse | MGI:MGI:3803393|PMID:18505825 | |
Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II | Sox4 | IDA | Mouse | MGI:MGI:5009531|PMID:18403418 | |
Biological Process | GO:0045727 | positive regulation of translation | SOX4 | IMP | Human | PMID:19234109 | |
Biological Process | GO:0002328 | pro-B cell differentiation | Sox4 | IMP | Mouse | MGI:MGI:80229|PMID:8614465 | |
Biological Process | GO:0050821 | protein stabilization | SOX4 | IMP | Human | PMID:17875931 | |
Biological Process | GO:0050821 | protein stabilization | Sox4 | IMP | Mouse | MGI:MGI:3768575|PMID:17875931 | |
Biological Process | GO:0043516 | regulation of DNA damage response, signal transduction by p53 class mediator | SOX4 | IMP | Human | PMID:19234109 | |
Biological Process | GO:0006355 | regulation of DNA-templated transcription | SOX4 | IDA | Human | PMID:16631117 | |
Biological Process | GO:0006355 | regulation of DNA-templated transcription | SOX4 | IDA | Human | PMID:7706298 | |
Biological Process | GO:0006355 | regulation of DNA-templated transcription | Sox4 | IMP | Mouse | MGI:MGI:5486619|PMID:23562159 | |
Biological Process | GO:0031647 | regulation of protein stability | SOX4 | IMP | Human | PMID:19234109 | |
Biological Process | GO:0001501 | skeletal system development | Sox4 | IMP | Mouse | MGI:MGI:5285157|PMID:20596238 | |
Biological Process | GO:0035019 | somatic stem cell population maintenance | Sox4 | IDA | Mouse | PMID:19379700 | |
Biological Process | GO:0021510 | spinal cord development | Sox4 | IMP | Mouse | MGI:MGI:4838379|PMID:20646169 | |
Biological Process | GO:0021522 | spinal cord motor neuron differentiation | Sox4 | IMP | Mouse | MGI:MGI:4838379|PMID:20646169 | |
Biological Process | GO:0048485 | sympathetic nervous system development | Sox4 | IMP | Mouse | MGI:MGI:4437361|PMID:20147379 | |
Biological Process | GO:0030217 | T cell differentiation | Sox4 | IMP | Mouse | MGI:MGI:3813366|PMID:9174623 | |
Biological Process | GO:0060412 | ventricular septum morphogenesis | Sox4 | IMP | Mouse | MGI:MGI:3603061|PMID:16109771 |
EXP Inferred from experiment |
IDA Inferred from direct assay |
IEP Inferred from expression pattern |
IGI Inferred from genetic interaction |
IMP Inferred from mutant phenotype |
IPI Inferred from physical interaction |
HTP Inferred from High Throughput Experiment |
HDA Inferred from High Throughput Direct Assay |
HMP Inferred from High Throughput Mutant Phenotype |
HGI Inferred from High Throughput Genetic Interaction |
HEP Inferred from High Throughput Expression Pattern |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/15/2024 MGI 6.24 |
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