Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SP100
  • Mouse genes Sp100
  • Rat genes Sp100
  • Zfish genes sp100.1,sp100.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sp100

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070087	chromo shadow domain binding	SP100	IPI	UniProtKB:P45973	Human	PMID:15882967
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	SP100	IDA		Human	PMID:14647468
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	SP100	IDA		Human	PMID:15247905
Molecular Function	GO:0042802	identical protein binding	SP100	IPI	UniProtKB:P23497	Human	PMID:9636146
Molecular Function	GO:0019900	kinase binding	SP100	IPI	UniProtKB:Q9H2X6	Human	PMID:14647468
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:O60934	Human	PMID:12470659
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:P14921	Human	PMID:15247905
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:P63165	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:P55854	Human	PMID:17000644
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:Q9UKL3	Human	PMID:17245429
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:P03169	Human	PMID:21880768
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:P63165	Human	PMID:21880768
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:P35609	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:P63165	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:Q14498-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:Q14D33	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:Q59GP6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:Q8TF65	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:Q92630	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:Q96GY0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:Q96JM7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:Q9Y228	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:Q9Y2J4-4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:Q9Y6K1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:V9HWG0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:G2XKQ0	Human	PMID:27211601
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:P35609	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:Q8TF65	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:Q9Y228	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SP100	IPI	UniProtKB:P45973	Human	PMID:9636147
Molecular Function	GO:0005515	protein binding	Sp100	IPI	UniProtKB:P45973	Mouse	MGI:MGI:1267116|PMID:9636146
Molecular Function	GO:0046983	protein dimerization activity	SP100	IPI	UniProtKB:P23497-2	Human	PMID:9636146
Molecular Function	GO:0019904	protein domain specific binding	SP100	IPI	UniProtKB:Q13185	Human	PMID:9636147
Cellular Component	GO:0000781	chromosome, telomeric region	SP100	HDA		Human	PMID:19135898
Cellular Component	GO:0005737	cytoplasm	SP100	IDA		Human	PMID:17245429
Cellular Component	GO:0016604	nuclear body	SP100	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SP100	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SP100	IDA		Human	PMID:17332504
Cellular Component	GO:0005634	nucleus	SP100	IDA		Human	PMID:25593309
Cellular Component	GO:0005634	nucleus	SP100	IDA		Human	PMID:8810287
Cellular Component	GO:0016605	PML body	SP100	IDA		Human	PMID:12470659
Cellular Component	GO:0016605	PML body	SP100	IDA		Human	PMID:14647468
Cellular Component	GO:0016605	PML body	SP100	IDA		Human	PMID:15247905
Cellular Component	GO:0016605	PML body	SP100	IDA		Human	PMID:17245429
Cellular Component	GO:0016605	PML body	SP100	IDA		Human	PMID:17332504
Cellular Component	GO:0016605	PML body	SP100	IDA		Human	PMID:9230084
Biological Process	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	SP100	IDA		Human	PMID:14647468
Biological Process	GO:0045185	maintenance of protein location	SP100	IDA		Human	PMID:12470659
Biological Process	GO:0043392	negative regulation of DNA binding	SP100	IDA		Human	PMID:15247905
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	SP100	IDA		Human	PMID:15247905
Biological Process	GO:0010596	negative regulation of endothelial cell migration	SP100	IMP		Human	PMID:15592518
Biological Process	GO:0046826	negative regulation of protein export from nucleus	SP100	IMP		Human	PMID:17245429
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SP100	IDA		Human	PMID:15247905
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	SP100	IMP		Human	PMID:14647468
Biological Process	GO:0045765	regulation of angiogenesis	SP100	IMP		Human	PMID:15592518
Biological Process	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	SP100	IMP		Human	PMID:17245429
Biological Process	GO:1902044	regulation of Fas signaling pathway	SP100	IMP		Human	PMID:17245429
Biological Process	GO:0034340	response to type I interferon	SP100	IDA		Human	PMID:15247905
Biological Process	GO:0034340	response to type I interferon	SP100	IMP		Human	PMID:8810287
Biological Process	GO:0034340	response to type I interferon	SP100	IDA		Human	PMID:9230084
Biological Process	GO:0034341	response to type II interferon	SP100	IMP		Human	PMID:8810287
Biological Process	GO:0034341	response to type II interferon	SP100	IDA		Human	PMID:9230084
Biological Process	GO:0000723	telomere maintenance	SP100	IMP		Human	PMID:15767676

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern