Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SP2
  • Mouse genes Sp2
  • Rat genes Sp2
  • Zfish genes sp2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	SP2	IDA		Human	PMID:10744779
Molecular Function	GO:0042826	histone deacetylase binding	SP2	IPI	UniProtKB:Q92769	Human	PMID:17827154
Molecular Function	GO:0005515	protein binding	SP2	IPI	UniProtKB:Q8N9N5	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	SP2	IPI	UniProtKB:P33993	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP2	IPI	UniProtKB:Q14192	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SP2	IPI	UniProtKB:Q8N9N5	Human	PMID:25416956
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SP2	IDA		Human	PMID:10744779
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	SP2	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	SP2	IDA		Human	GO_REF:0000052
Biological Process	GO:0072359	circulatory system development	Sp2	IMP	MGI:MGI:4441277	Mouse	PMID:20221402
Biological Process	GO:0048568	embryonic organ development	Sp2	IMP	MGI:MGI:4441280	Mouse	PMID:20221402
Biological Process	GO:0048144	fibroblast proliferation	Sp2	IMP	MGI:MGI:4441280	Mouse	PMID:20221402
Biological Process	GO:0001701	in utero embryonic development	Sp2	IMP	MGI:MGI:4441277	Mouse	PMID:20221402
Biological Process	GO:0035264	multicellular organism growth	Sp2	IMP	MGI:MGI:4441277	Mouse	PMID:20221402
Biological Process	GO:0035264	multicellular organism growth	Sp2	IMP	MGI:MGI:4441280	Mouse	PMID:20221402
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SP2	IDA		Human	PMID:10744779

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern