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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Sp3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sp3
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003682chromatin bindingSp3IDAMousePMID:15522233
Molecular FunctionGO:0000987cis-regulatory region sequence-specific DNA bindingSp3IDAMousePMID:19943855
Molecular FunctionGO:0000987cis-regulatory region sequence-specific DNA bindingSp3IDAMousePMID:15511642
Molecular FunctionGO:0003677DNA bindingSp3IDAMousePMID:14630713
Molecular FunctionGO:0001227DNA-binding transcription repressor activity, RNA polymerase II-specificSp3IDAMouseMGI:MGI:5009400|PMID:17130167
Molecular FunctionGO:0001227DNA-binding transcription repressor activity, RNA polymerase II-specificSp3IDARatPMID:17130167|RGD:8553999
Molecular FunctionGO:0003690double-stranded DNA bindingSp3IDAMousePMID:15282343
Molecular FunctionGO:0005515protein bindingSP3IPIUniProtKB:Q14527HumanPMID:10391891
Molecular FunctionGO:0005515protein bindingSP3IPIUniProtKB:P03372HumanPMID:10816575
Molecular FunctionGO:0005515protein bindingSP3IPIUniProtKB:Q13547HumanPMID:12176973
Molecular FunctionGO:0005515protein bindingSP3IPIUniProtKB:Q92769HumanPMID:12176973
Molecular FunctionGO:0005515protein bindingSP3IPIUniProtKB:P42858HumanPMID:17500595
Molecular FunctionGO:0005515protein bindingSP3IPIUniProtKB:P03372HumanPMID:31527615
Molecular FunctionGO:0005515protein bindingSP3IPIUniProtKB:P14678-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSP3IPIUniProtKB:Q5MJ10HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSP3IPIUniProtKB:Q6MZP7HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSP3IPIUniProtKB:Q7Z3K3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSP3IPIUniProtKB:Q96BD5HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSP3IPIUniProtKB:Q96Q77HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSP3IPIUniProtKB:P42858HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingSp3IPIUniProtKB:Q9Z2D6MouseMGI:MGI:6716954|PMID:20385708
Molecular FunctionGO:0000978RNA polymerase II cis-regulatory region sequence-specific DNA bindingSp3IDAMousePMID:17670746
Molecular FunctionGO:0000978RNA polymerase II cis-regulatory region sequence-specific DNA bindingSp3IDAMousePMID:15094381
Molecular FunctionGO:0000978RNA polymerase II cis-regulatory region sequence-specific DNA bindingSp3IGIUniProtKB:P01139RatPMID:10362258|RGD:13506263
Molecular FunctionGO:0000977RNA polymerase II transcription regulatory region sequence-specific DNA bindingSP3IDAHumanPMID:14979875
Molecular FunctionGO:0000977RNA polymerase II transcription regulatory region sequence-specific DNA bindingSp3IMPRatPMID:14979875|RGD:10047233
Molecular FunctionGO:0061629RNA polymerase II-specific DNA-binding transcription factor bindingSP3IPIUniProtKB:Q13127HumanPMID:17130167
Molecular FunctionGO:0061629RNA polymerase II-specific DNA-binding transcription factor bindingSp3IPIUniProtKB:Q8VIG1MouseMGI:MGI:5009400|PMID:17130167
Molecular FunctionGO:0061629RNA polymerase II-specific DNA-binding transcription factor bindingSp3IPIUniProtKB:O54963RatPMID:17130167|RGD:8553999
Molecular FunctionGO:1990837sequence-specific double-stranded DNA bindingSP3IDAHumanPMID:28473536
Cellular ComponentGO:0005829cytosolSP3IDAHumanGO_REF:0000052
Cellular ComponentGO:0005654nucleoplasmSP3IDAHumanGO_REF:0000052
Cellular ComponentGO:0005634nucleusSp3IDAMousePMID:15282343
Cellular ComponentGO:0005634nucleusSp3IDAMousePMID:15817708
Cellular ComponentGO:0005634nucleusSp3IDARatPMID:14979875|RGD:10047233
Cellular ComponentGO:0032993protein-DNA complexSp3IPIUniProtKB:A0A0G2QC09,UniProtKB:Q01714RatPMID:10362258|RGD:13506263
Cellular ComponentGO:0017053transcription repressor complexSp3IDAMouseMGI:MGI:5009400|PMID:17130167
Cellular ComponentGO:0017053transcription repressor complexSp3IDARatPMID:17130167|RGD:8553999
Biological ProcessGO:0030183B cell differentiationSp3IMPMGI:MGI:2182438MousePMID:12676787
Biological ProcessGO:0060216definitive hemopoiesisSp3IGIMGI:MGI:98372MousePMID:17584888
Biological ProcessGO:0048596embryonic camera-type eye morphogenesisSp3IGIMGI:MGI:98372MousePMID:17584888
Biological ProcessGO:0001892embryonic placenta developmentSp3IGIMGI:MGI:98372MousePMID:17584888
Biological ProcessGO:0060136embryonic process involved in female pregnancySp3IGIMGI:MGI:98372MousePMID:17584888
Biological ProcessGO:0048706embryonic skeletal system developmentSp3IGIMGI:MGI:98372MousePMID:17584888
Biological ProcessGO:0043353enucleate erythrocyte differentiationSp3IGIMGI:MGI:98372MousePMID:17584888
Biological ProcessGO:0030218erythrocyte differentiationSp3IMPMGI:MGI:2182438MousePMID:12676787
Biological ProcessGO:0030851granulocyte differentiationSp3IMPMGI:MGI:2182438MousePMID:12676787
Biological ProcessGO:0001701in utero embryonic developmentSp3IGIMGI:MGI:98372MousePMID:17584888
Biological ProcessGO:0001889liver developmentSp3IGIMGI:MGI:98372MousePMID:17584888
Biological ProcessGO:0030324lung developmentSp3IGIMGI:MGI:98372MousePMID:17584888
Biological ProcessGO:0030219megakaryocyte differentiationSp3IGIMGI:MGI:98372MousePMID:17584888
Biological ProcessGO:0030224monocyte differentiationSp3IMPMGI:MGI:2182438MousePMID:12676787
Biological ProcessGO:0002318myeloid progenitor cell differentiationSp3IGIMGI:MGI:98372MousePMID:17584888
Biological ProcessGO:0001779natural killer cell differentiationSp3IMPMGI:MGI:2182438MousePMID:12676787
Biological ProcessGO:0045892negative regulation of DNA-templated transcriptionSP3IMPHumanPMID:20091743
Biological ProcessGO:0045892negative regulation of DNA-templated transcriptionSp3IDAMouseMGI:MGI:5009400|PMID:17130167
Biological ProcessGO:0045892negative regulation of DNA-templated transcriptionSp3IDARatPMID:17130167|RGD:8553999
Biological ProcessGO:0001503ossificationSp3IGIMGI:MGI:98372MousePMID:17584888
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionSP3IDAHumanPMID:12771217
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IISP3IGIUniProtKB:P08047HumanPMID:14979875
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IISP3IMPHumanPMID:14979875
Biological ProcessGO:0006355regulation of DNA-templated transcriptionSP3IDAHumanPMID:12560508
Biological ProcessGO:0030217T cell differentiationSp3IMPMGI:MGI:2182438MousePMID:12676787
Biological ProcessGO:0001829trophectodermal cell differentiationSp3IGIMGI:MGI:98372MousePMID:17584888

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory