Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SP5
  • Mouse genes Sp5
  • Rat genes Sp5
  • Zfish genes sp5a,sp5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sp5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Sp5	IDA		Mouse	MGI:MGI:5566772|PMID:17090534
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Sp5	IDA		Mouse	MGI:MGI:1927252|PMID:11071760
Molecular Function	GO:0043565	sequence-specific DNA binding	Sp5	IDA		Mouse	PMID:11071760
Biological Process	GO:0060349	bone morphogenesis	Sp5	IGI	MGI:MGI:98472	Mouse	PMID:11071760
Biological Process	GO:0071407	cellular response to organic cyclic compound	Sp5	IDA		Mouse	PMID:25535395
Biological Process	GO:0048332	mesoderm morphogenesis	sp5a	IGI	ZFIN:ZDB-MRPHLNO-050607-2,ZFIN:ZDB-MRPHLNO-050901-1	Zfish	PMID:15797017
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Sp5	IDA		Mouse	MGI:MGI:5566772|PMID:17090534
Biological Process	GO:0036342	post-anal tail morphogenesis	Sp5	IGI	MGI:MGI:98472	Mouse	PMID:11071760

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern