Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SP8
  • Mouse genes Sp8
  • Rat genes Sp8
  • Zfish genes sp8a,sp8b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sp8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003690	double-stranded DNA binding	sp8b	IDA		Zfish	PMID:15464585
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	SP8	IDA		Human	PMID:28473536
Biological Process	GO:0009953	dorsal/ventral pattern formation	Sp8	IMP	MGI:MGI:2684137	Mouse	PMID:14597661
Biological Process	GO:0030326	embryonic limb morphogenesis	Sp8	IMP		Mouse	MGI:MGI:3526745|PMID:15358670
Biological Process	GO:0030326	embryonic limb morphogenesis	Sp8	IMP	MGI:MGI:2684137	Mouse	PMID:14597661
Biological Process	GO:0030326	embryonic limb morphogenesis	sp8b	IMP		Zfish	PMID:15358670|ZFIN:ZDB-PUB-040914-5
Biological Process	GO:0035118	embryonic pectoral fin morphogenesis	sp8b	IMP		Zfish	PMID:15358670
Biological Process	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway	sp8b	IMP		Zfish	PMID:15358670
Biological Process	GO:0009954	proximal/distal pattern formation	Sp8	IMP	MGI:MGI:2684137	Mouse	PMID:14597661

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern