Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPATA2
  • Mouse genes Spata2
  • Rat genes Spata2
  • Zfish genes spata2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spata2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q9NQC7	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q9NQC7	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:P14373	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q9BRK4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q9Y6D9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q9NQC7	Human	PMID:27307491
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q96EP0	Human	PMID:27458237
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q9NQC7	Human	PMID:27458237
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q96EP0	Human	PMID:27545878
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q9NQC7	Human	PMID:27545878
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q96EP0	Human	PMID:27591049
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q9NQC7	Human	PMID:27591049
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:P14373	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q08379	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:O95872	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q15025	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q53TS8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q5JVL4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q68D86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q92993	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q96BZ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q9BVG8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q9NU19	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q9UI12	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:Q9Y2P0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:X5D778	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPATA2	IPI	UniProtKB:P14136	Human	PMID:32814053
Molecular Function	GO:0044877	protein-containing complex binding	SPATA2	IDA		Human	PMID:27545878
Molecular Function	GO:0030159	signaling receptor complex adaptor activity	SPATA2	IDA		Human	PMID:27545878
Molecular Function	GO:1990381	ubiquitin-specific protease binding	SPATA2	IDA		Human	PMID:27545878
Cellular Component	GO:0005737	cytoplasm	SPATA2	IDA		Human	PMID:10222154
Cellular Component	GO:0005737	cytoplasm	Spata2	IDA		Mouse	PMID:29025062
Cellular Component	GO:0001650	fibrillar center	SPATA2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SPATA2	IDA		Human	GO_REF:0000052
Biological Process	GO:0070266	necroptotic process	Spata2	IMP		Mouse	PMID:27545878
Biological Process	GO:0070536	protein K63-linked deubiquitination	SPATA2	IDA		Human	PMID:27458237
Biological Process	GO:0070536	protein K63-linked deubiquitination	SPATA2	IDA		Human	PMID:27591049
Biological Process	GO:1990108	protein linear deubiquitination	SPATA2	IDA		Human	PMID:27458237
Biological Process	GO:1990108	protein linear deubiquitination	SPATA2	IDA		Human	PMID:27591049
Biological Process	GO:1990108	protein linear deubiquitination	Spata2	IMP		Mouse	MGI:MGI:5912943|PMID:28701375
Biological Process	GO:0050727	regulation of inflammatory response	SPATA2	IDA		Human	PMID:27591049
Biological Process	GO:0060544	regulation of necroptotic process	SPATA2	IDA		Human	PMID:27307491
Biological Process	GO:0060544	regulation of necroptotic process	SPATA2	IDA		Human	PMID:27458237
Biological Process	GO:0060544	regulation of necroptotic process	SPATA2	IDA		Human	PMID:27545878
Biological Process	GO:0060544	regulation of necroptotic process	Spata2	IMP		Mouse	MGI:MGI:5912943|PMID:28701375
Biological Process	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	SPATA2	IDA		Human	PMID:27307491
Biological Process	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	SPATA2	IDA		Human	PMID:27458237
Biological Process	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	SPATA2	IDA		Human	PMID:27545878
Biological Process	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	SPATA2	IDA		Human	PMID:27591049
Biological Process	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	Spata2	IMP		Mouse	MGI:MGI:5912943|PMID:28701375
Biological Process	GO:0072520	seminiferous tubule development	Spata2	IMP	MGI:6093706	Mouse	PMID:29025062
Biological Process	GO:0007283	spermatogenesis	Spata2	IMP	MGI:6093706	Mouse	PMID:29025062

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern