Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPCS1
  • Mouse genes Spcs1
  • Rat genes Spcs1
  • Zfish genes spcs1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spcs1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPCS1	IPI	UniProtKB:Q99IB8:PRO_0000045596	Human	PMID:24009510
Molecular Function	GO:0005515	protein binding	SPCS1	IPI	UniProtKB:Q99IB8:PRO_0000045598	Human	PMID:24009510
Molecular Function	GO:0005515	protein binding	SPCS1	IPI	UniProtKB:P27395:PRO_0000037842	Human	PMID:29593046
Molecular Function	GO:0005515	protein binding	SPCS1	IPI	UniProtKB:Q32ZE1:PRO_0000435837	Human	PMID:29593046
Molecular Function	GO:0005515	protein binding	SPCS1	IPI	UniProtKB:Q9Q6P4:PRO_0000441585	Human	PMID:29593046
Molecular Function	GO:0005515	protein binding	SPCS1	IPI	UniProtKB:P61009,UniProtKB:P67812,UniProtKB:Q15005	Human	PMID:34388369
Molecular Function	GO:0005515	protein binding	SPCS1	IPI	UniProtKB:P61009,UniProtKB:Q15005,UniProtKB:Q9BY50	Human	PMID:34388369
Molecular Function	GO:0043022	ribosome binding	Spcs1	IDA		Mouse	PMID:16705175
Cellular Component	GO:0005789	endoplasmic reticulum membrane	SPCS1	IDA		Human	PMID:8632014
Cellular Component	GO:0005787	signal peptidase complex	SPCS1	IPI		Human	PMID:34388369
Biological Process	GO:0006465	signal peptide processing	SPCS1	IDA		Human	PMID:34388369
Biological Process	GO:0019082	viral protein processing	SPCS1	IMP		Human	PMID:27383988
Biological Process	GO:0019068	virion assembly	SPCS1	IMP		Human	PMID:24009510
Biological Process	GO:0019068	virion assembly	SPCS1	IMP		Human	PMID:29593046

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern