Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPCS3
  • Mouse genes Spcs3
  • Rat genes Spcs3
  • Zfish genes spcs3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spcs3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPCS3	IPI	UniProtKB:P54253	Human	PMID:25959826
Molecular Function	GO:0005515	protein binding	SPCS3	IPI	UniProtKB:Q9BY50	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	SPCS3	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SPCS3	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SPCS3	IPI	UniProtKB:P67812	Human	PMID:34388369
Molecular Function	GO:0005515	protein binding	SPCS3	IPI	UniProtKB:P67812,UniProtKB:Q15005,UniProtKB:Q9Y6A9	Human	PMID:34388369
Molecular Function	GO:0005515	protein binding	SPCS3	IPI	UniProtKB:Q15005,UniProtKB:Q9BY50,UniProtKB:Q9Y6A9	Human	PMID:34388369
Molecular Function	GO:0005515	protein binding	SPCS3	IPI	UniProtKB:Q9BY50	Human	PMID:34388369
Cellular Component	GO:0005783	endoplasmic reticulum	SPCS3	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005787	signal peptidase complex	SPCS3	IPI		Human	PMID:34388369
Biological Process	GO:0006508	proteolysis	SPCS3	IDA		Human	PMID:27499293
Biological Process	GO:0006465	signal peptide processing	SPCS3	IDA		Human	PMID:34388369
Biological Process	GO:0019082	viral protein processing	SPCS3	IMP		Human	PMID:27383988

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern