Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPINDOC
  • Mouse genes Spindoc
  • Rat genes Spindoc
  • Zfish genes si:dkey-28a3.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spindoc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPINDOC	IPI	UniProtKB:Q56A73|UniProtKB:Q5JUX0|UniProtKB:Q99865|UniProtKB:Q9BPZ2|UniProtKB:Q9Y657	Human	PMID:29061846
Molecular Function	GO:0005515	protein binding	SPINDOC	IPI	UniProtKB:O75928-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPINDOC	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPINDOC	IPI	UniProtKB:P31930	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SPINDOC	IDA		Human	PMID:34737271
Cellular Component	GO:0005634	nucleus	SPINDOC	IDA		Human	PMID:29061846
Cellular Component	GO:0090734	site of DNA damage	SPINDOC	IDA		Human	PMID:34737271
Biological Process	GO:0006974	DNA damage response	SPINDOC	IDA		Human	PMID:34737271
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	SPINDOC	IDA		Human	PMID:29061846
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Spindoc	IDA		Mouse	MGI:MGI:6094488|PMID:29061846
Biological Process	GO:0010835	regulation of protein ADP-ribosylation	SPINDOC	IDA		Human	PMID:34737271
Biological Process	GO:0010835	regulation of protein ADP-ribosylation	Spindoc	IMP		Mouse	MGI:MGI:6826768|PMID:34737271

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern