Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPOCK2
  • Mouse genes Spock2
  • Rat genes Spock2
  • Zfish genes spock2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spock2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	SPOCK2	IDA		Human	PMID:10386950
Molecular Function	GO:0050840	extracellular matrix binding	Spock2	IDA		Mouse	PMID:18757743
Molecular Function	GO:0005539	glycosaminoglycan binding	Spock2	IDA		Mouse	PMID:18757743
Molecular Function	GO:0005515	protein binding	SPOCK2	IPI	UniProtKB:Q9H0I2	Human	PMID:32296183
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Spock2	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Spock2	IEP		Mouse	PMID:20439489
Biological Process	GO:0030198	extracellular matrix organization	Spock2	IDA		Mouse	PMID:18757743
Biological Process	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	Spock2	IDA		Mouse	PMID:18757743
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	Spock2	IDA		Mouse	PMID:18757743

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern