Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPOPL
  • Mouse genes Spopl
  • Rat genes Spopl
  • Zfish genes spopla,spoplb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spopl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPOPL	IPI	UniProtKB:O15131	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SPOPL	IPI	UniProtKB:O15131	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SPOPL	IPI	UniProtKB:P15336	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPOPL	IPI	UniProtKB:P28702	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPOPL	IPI	UniProtKB:Q02930-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPOPL	IPI	UniProtKB:Q99836	Human	PMID:32296183
Cellular Component	GO:0031463	Cul3-RING ubiquitin ligase complex	SPOPL	IDA		Human	PMID:22632832
Biological Process	GO:0031397	negative regulation of protein ubiquitination	SPOPL	IMP		Human	PMID:22632832
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	SPOPL	IMP		Human	PMID:22632832

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern