Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPRED3
  • Mouse genes Spred3
  • Rat genes Spred3
  • Zfish genes spred3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spred3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0005886	plasma membrane	Spred3	IDA		Mouse	PMID:12646235
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	Spred3	IDA		Mouse	MGI:MGI:6414689|PMID:25576668
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Spred3	IDA		Mouse	MGI:MGI:6414698|PMID:29501879
Biological Process	GO:1902747	negative regulation of lens fiber cell differentiation	Spred3	IDA		Mouse	MGI:MGI:6414698|PMID:29501879
Biological Process	GO:0043409	negative regulation of MAPK cascade	Spred3	IMP		Mouse	PMID:12646235
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	Spred3	IDA		Mouse	MGI:MGI:6414689|PMID:25576668

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern