Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPRR1A
  • Mouse genes Sprr1a
  • Rat genes Sprr1a
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sprr1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPRR1A	IPI	UniProtKB:P22735	Human	PMID:10066784
Molecular Function	GO:0005515	protein binding	SPRR1A	IPI	UniProtKB:Q8NBF1	Human	PMID:32296183
Molecular Function	GO:0030280	structural constituent of skin epidermis	SPRR1A	IDA		Human	PMID:7543090
Cellular Component	GO:0071944	cell periphery	Sprr1a	IDA		Mouse	PMID:11698679
Cellular Component	GO:0001533	cornified envelope	SPRR1A	IDA		Human	PMID:10908733
Cellular Component	GO:0001533	cornified envelope	SPRR1A	IDA		Human	PMID:7543090
Biological Process	GO:0030216	keratinocyte differentiation	SPRR1A	IDA		Human	PMID:10908733
Biological Process	GO:0018149	peptide cross-linking	SPRR1A	IDA		Human	PMID:10908733
Biological Process	GO:0018149	peptide cross-linking	SPRR1A	IDA		Human	PMID:7543090

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern