Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPSB2
  • Mouse genes Spsb2
  • Rat genes Spsb2
  • Zfish genes si:ch1073-228j22.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Spsb2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:Q15369	Human	PMID:15601820
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:Q15369	Human	PMID:19159283
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:P09052	Human	PMID:20561531
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:P35228	Human	PMID:21199876
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:Q93034	Human	PMID:21199876
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:Q99873	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:Q92569	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:Q16656-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:Q53EP0-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:Q6P9E2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:Q96GM5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:G5E9A7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:O60260-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:O60333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:P08670	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:P16284	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:P61086	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SPSB2	IPI	UniProtKB:Q9Y3C5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Spsb2	IPI	UniProtKB:P29477	Mouse	MGI:MGI:4820465|PMID:20603330
Molecular Function	GO:0005515	protein binding	Spsb2	IPI	UniProtKB:Q96IZ0	Mouse	MGI:MGI:5917390|PMID:16369487
Molecular Function	GO:0005515	protein binding	Spsb2	IPI	UniProtKB:Q96IZ0	Mouse	MGI:MGI:5532915|PMID:20561531
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	SPSB2	IPI	UniProtKB:P35228|UniProtKB:Q15369	Human	PMID:21199876
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	SPSB2	IPI	UniProtKB:P35228|UniProtKB:Q93034	Human	PMID:21199876
Cellular Component	GO:0005829	cytosol	SPSB2	IDA		Human	PMID:21199876
Biological Process	GO:0016567	protein ubiquitination	SPSB2	IDA		Human	PMID:21199876
Biological Process	GO:0016567	protein ubiquitination	Spsb2	IDA		Mouse	MGI:MGI:4820465|PMID:20603330
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	SPSB2	IDA		Human	PMID:21199876
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Spsb2	IMP		Mouse	MGI:MGI:4820465|PMID:20603330

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern