Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPTBN1
  • Mouse genes Sptbn1
  • Rat genes Sptbn1
  • Zfish genes sptbn1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sptbn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030506	ankyrin binding	SPTBN1	IPI	UniProtKB:Q01484	Human	PMID:15262991
Molecular Function	GO:0045296	cadherin binding	SPTBN1	HDA		Human	PMID:25468996
Molecular Function	GO:0051020	GTPase binding	SPTBN1	IPI	UniProtKB:P32455	Human	PMID:24337748
Molecular Function	GO:0005515	protein binding	SPTBN1	IPI	UniProtKB:P35240-3	Human	PMID:11779178
Molecular Function	GO:0005515	protein binding	SPTBN1	IPI	UniProtKB:P02549	Human	PMID:12820899
Molecular Function	GO:0005515	protein binding	SPTBN1	IPI	UniProtKB:Q13813	Human	PMID:12820899
Molecular Function	GO:0005515	protein binding	SPTBN1	IPI	UniProtKB:Q01484	Human	PMID:15262991
Molecular Function	GO:0005515	protein binding	SPTBN1	IPI	UniProtKB:Q99459	Human	PMID:17043677
Molecular Function	GO:0005515	protein binding	SPTBN1	IPI	UniProtKB:Q9NRI5	Human	PMID:17043677
Molecular Function	GO:0005515	protein binding	SPTBN1	IPI	UniProtKB:Q99459	Human	PMID:20467437
Molecular Function	GO:0005515	protein binding	SPTBN1	IPI	UniProtKB:Q9NRI5	Human	PMID:29961565
Molecular Function	GO:0005515	protein binding	SPTBN1	IPI	UniProtKB:Q13813	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	SPTBN1	IPI	UniProtKB:Q99459	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	SPTBN1	IPI	UniProtKB:Q9NRI5	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	SPTBN1	IPI	UniProtKB:P35240	Human	PMID:9537418
Molecular Function	GO:0005515	protein binding	SPTBN1	IPI	UniProtKB:P35240-3	Human	PMID:9537418
Molecular Function	GO:0005515	protein binding	Sptbn1	IPI	UniProtKB:Q96A23	Mouse	MGI:MGI:5294308|PMID:12522145
Molecular Function	GO:0005515	protein binding	Sptbn1	IPI	PR:Q8C8R3	Mouse	PMID:15262991
Molecular Function	GO:0005515	protein binding	Sptbn1	IPI	PR:Q8BUN5	Mouse	PMID:12543979
Molecular Function	GO:0005515	protein binding	Sptbn1	IPI	PR:P97471	Mouse	PMID:12543979
Molecular Function	GO:0044877	protein-containing complex binding	Sptbn1	IPI	RGD:620460	Rat	PMID:15331416|RGD:1600864
Molecular Function	GO:0003723	RNA binding	SPTBN1	HDA		Human	PMID:22681889
Molecular Function	GO:0005200	structural constituent of cytoskeleton	SPTBN1	IMP		Human	PMID:17620337
Molecular Function	GO:0005200	structural constituent of cytoskeleton	SPTBN1	IMP		Human	PMID:34211179
Cellular Component	GO:0030673	axolemma	Sptbn1	IDA		Mouse	MGI:MGI:5296417|PMID:21966409
Cellular Component	GO:0030863	cortical cytoskeleton	Sptbn1	IDA		Mouse	PMID:18723693
Cellular Component	GO:0032437	cuticular plate	Sptbn1	IDA		Mouse	PMID:18796539
Cellular Component	GO:0005737	cytoplasm	SPTBN1	IDA		Human	PMID:9537418
Cellular Component	GO:0005829	cytosol	SPTBN1	IDA		Human	PMID:34211179
Cellular Component	GO:0070062	extracellular exosome	SPTBN1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	SPTBN1	HDA		Human	PMID:20458337
Cellular Component	GO:0098978	glutamatergic synapse	Sptbn1	IDA		Rat	PMID:27220554|RGD:13702304
Cellular Component	GO:0031430	M band	Sptbn1	IDA		Mouse	MGI:MGI:3056879|PMID:15262991
Cellular Component	GO:0016020	membrane	Sptbn1	IDA		Mouse	PMID:18723693
Cellular Component	GO:0005730	nucleolus	SPTBN1	IDA		Human	PMID:9537418
Cellular Component	GO:0005634	nucleus	Sptbn1	IDA		Mouse	PMID:12543979
Cellular Component	GO:0005886	plasma membrane	SPTBN1	IDA		Human	PMID:34211179
Cellular Component	GO:0005886	plasma membrane	Sptbn1	IDA		Mouse	PMID:12543979
Cellular Component	GO:0098794	postsynapse	Sptbn1	IDA		Rat	PMID:27220554|RGD:13702304
Cellular Component	GO:0014069	postsynaptic density	Sptbn1	IDA		Mouse	PMID:17114649
Cellular Component	GO:0032991	protein-containing complex	Sptbn1	IDA		Rat	PMID:15331416|RGD:1600864
Biological Process	GO:0030036	actin cytoskeleton organization	SPTBN1	IMP		Human	PMID:34211179
Biological Process	GO:0007417	central nervous system development	SPTBN1	IMP		Human	PMID:34211179
Biological Process	GO:0007417	central nervous system development	Sptbn1	IMP		Mouse	MGI:MGI:6742151|PMID:34211179
Biological Process	GO:0021556	central nervous system formation	SPTBN1	IMP		Human	PMID:34211179
Biological Process	GO:0021556	central nervous system formation	Sptbn1	IMP		Mouse	MGI:MGI:6742151|PMID:34211179
Biological Process	GO:0007182	common-partner SMAD protein phosphorylation	Sptbn1	IDA		Mouse	PMID:12543979
Biological Process	GO:0043001	Golgi to plasma membrane protein transport	SPTBN1	IMP		Human	PMID:17620337
Biological Process	GO:0071709	membrane assembly	SPTBN1	IMP		Human	PMID:17620337
Biological Process	GO:0000281	mitotic cytokinesis	SPTBN1	IMP		Human	PMID:17620337
Biological Process	GO:0007009	plasma membrane organization	SPTBN1	IMP		Human	PMID:17620337
Biological Process	GO:0032743	positive regulation of interleukin-2 production	SPTBN1	IMP		Human	PMID:24337748
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	SPTBN1	IMP		Human	PMID:24337748
Biological Process	GO:0072659	protein localization to plasma membrane	SPTBN1	IMP		Human	PMID:17620337
Biological Process	GO:0072659	protein localization to plasma membrane	Sptbn1	IMP		Mouse	MGI:MGI:3722194|PMID:17620337
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	SPTBN1	IGI	UniProtKB:P32455	Human	PMID:24337748
Biological Process	GO:0060390	regulation of SMAD protein signal transduction	Sptbn1	IDA		Mouse	PMID:12543979

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern