Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPTBN2
  • Mouse genes Sptbn2
  • Rat genes Sptbn2
  • Zfish genes sptbn2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sptbn2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	SPTBN2	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	Sptbn2	IPI	RGD:619722	Rat	PMID:9704016|RGD:70020
Molecular Function	GO:0099186	structural constituent of postsynapse	Sptbn2	IDA		Mouse	PMID:28576936
Molecular Function	GO:0099186	structural constituent of postsynapse	Sptbn2	IMP		Mouse	PMID:28576936
Cellular Component	GO:0016324	apical plasma membrane	Sptbn2	IDA		Mouse	PMID:21705333
Cellular Component	GO:0005829	cytosol	SPTBN2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005768	endosome	Sptbn2	IDA		Rat	PMID:12411436|RGD:631918
Cellular Component	GO:0005615	extracellular space	SPTBN2	HDA		Human	PMID:22664934
Cellular Component	GO:0098978	glutamatergic synapse	Sptbn2	IDA		Mouse	PMID:22090485
Cellular Component	GO:0098978	glutamatergic synapse	Sptbn2	IMP		Mouse	PMID:22090485
Cellular Component	GO:0098978	glutamatergic synapse	Sptbn2	IDA		Mouse	PMID:28576936
Cellular Component	GO:0098978	glutamatergic synapse	Sptbn2	IMP		Mouse	PMID:28576936
Cellular Component	GO:0000139	Golgi membrane	Sptbn2	IDA		Rat	PMID:12411436|RGD:631918
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SPTBN2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043025	neuronal cell body	Sptbn2	IDA		Mouse	PMID:18796539
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Sptbn2	IDA		Mouse	PMID:22090485
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Sptbn2	IMP		Mouse	PMID:22090485
Cellular Component	GO:0033010	paranodal junction	Sptbn2	IDA		Mouse	PMID:16687515
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Sptbn2	IDA		Rat	PMID:12411436|RGD:631918
Cellular Component	GO:0005886	plasma membrane	SPTBN2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Sptbn2	IDA		Rat	PMID:9704016|RGD:70020
Cellular Component	GO:0099189	postsynaptic spectrin-associated cytoskeleton	Sptbn2	IDA		Mouse	PMID:28576936
Cellular Component	GO:0098793	presynapse	Sptbn2	IDA		Mouse	PMID:3531427
Cellular Component	GO:0008091	spectrin	SPTBN2	IDA		Human	PMID:9826670
Cellular Component	GO:0008021	synaptic vesicle	Sptbn2	IDA		Rat	PMID:9704016|RGD:70020
Biological Process	GO:0030534	adult behavior	Sptbn2	IMP	MGI:MGI:4127354	Mouse	PMID:20231455
Biological Process	GO:0071361	cellular response to ethanol	Sptbn2	IEP		Rat	PMID:12411436|RGD:631918
Biological Process	GO:0021692	cerebellar Purkinje cell layer morphogenesis	Sptbn2	IMP	MGI:MGI:4127354	Mouse	PMID:20231455
Biological Process	GO:0035264	multicellular organism growth	Sptbn2	IMP	MGI:MGI:4127354	Mouse	PMID:20231455
Biological Process	GO:0099173	postsynapse organization	Sptbn2	IMP		Mouse	PMID:22090485
Biological Process	GO:0099173	postsynapse organization	Sptbn2	IDA		Mouse	PMID:22090485
Biological Process	GO:0099150	regulation of postsynaptic specialization assembly	Sptbn2	IDA		Mouse	PMID:28576936
Biological Process	GO:0099150	regulation of postsynaptic specialization assembly	Sptbn2	IMP		Mouse	PMID:28576936
Biological Process	GO:0007416	synapse assembly	Sptbn2	IMP	MGI:MGI:4127354	Mouse	PMID:20231455
Biological Process	GO:0016079	synaptic vesicle exocytosis	Sptbn2	IPI	UniProtKB:O15020	Rat	PMID:9826670|RGD:8553838
Biological Process	GO:0016192	vesicle-mediated transport	SPTBN2	IDA		Human	PMID:9826670

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern