Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPTBN4
  • Mouse genes Sptbn4
  • Rat genes Sptbn4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sptbn4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Sptbn4	IDA		Mouse	PMID:20877009
Molecular Function	GO:0030506	ankyrin binding	SPTBN4	IDA		Human	PMID:11294830
Molecular Function	GO:0030506	ankyrin binding	Sptbn4	IDA		Mouse	MGI:MGI:2181223|PMID:11807096
Molecular Function	GO:0019902	phosphatase binding	SPTBN4	IPI	UniProtKB:Q16849	Human	PMID:11086001
Molecular Function	GO:0005515	protein binding	SPTBN4	IPI	UniProtKB:Q16849	Human	PMID:11086001
Molecular Function	GO:0005515	protein binding	SPTBN4	IPI	UniProtKB:Q9NRI5	Human	PMID:12812986
Molecular Function	GO:0005515	protein binding	Sptbn4	IPI	UniProtKB:A0A088MLT8	Mouse	MGI:MGI:5888972|PMID:27979964
Molecular Function	GO:0005515	protein binding	Sptbn4	IPI	PR:G5E8K5	Mouse	PMID:20877009
Molecular Function	GO:0005515	protein binding	Sptbn4	IPI	UniProtKB:E9Q1T1	Mouse	PMID:20877009
Molecular Function	GO:0030507	spectrin binding	Sptbn4	IDA		Mouse	PMID:20877009
Cellular Component	GO:0005884	actin filament	Sptbn4	IDA		Mouse	MGI:MGI:2181223|PMID:11807096
Cellular Component	GO:0005912	adherens junction	Sptbn4	IDA		Mouse	MGI:MGI:2181223|PMID:11807096
Cellular Component	GO:0030424	axon	Sptbn4	IDA		Mouse	PMID:15381686
Cellular Component	GO:0030424	axon	Sptbn4	IDA		Rat	PMID:17709431|RGD:14392774
Cellular Component	GO:0043203	axon hillock	Sptbn4	IDA		Mouse	PMID:15381686
Cellular Component	GO:0043194	axon initial segment	Sptbn4	IDA		Mouse	MGI:MGI:5883190|PMID:27356871
Cellular Component	GO:0043194	axon initial segment	Sptbn4	IDA		Mouse	MGI:MGI:2181223|PMID:11807096
Cellular Component	GO:0043194	axon initial segment	Sptbn4	IDA		Mouse	PMID:20877009
Cellular Component	GO:0043194	axon initial segment	Sptbn4	IDA		Mouse	PMID:26671463
Cellular Component	GO:0043194	axon initial segment	Sptbn4	IDA		Rat	PMID:11086001|RGD:8553353
Cellular Component	GO:0043194	axon initial segment	Sptbn4	IDA		Rat	PMID:17709431|RGD:14392774
Cellular Component	GO:0043194	axon initial segment	Sptbn4	IDA		Rat	PMID:28426968|RGD:13514087
Cellular Component	GO:0070852	cell body fiber	Sptbn4	IDA		Mouse	PMID:18796539
Cellular Component	GO:0005737	cytoplasm	SPTBN4	IDA		Human	PMID:11294830
Cellular Component	GO:0005737	cytoplasm	Sptbn4	IDA		Rat	PMID:11086001|RGD:8553353
Cellular Component	GO:0070062	extracellular exosome	SPTBN4	HDA		Human	PMID:23533145
Cellular Component	GO:0014704	intercalated disc	Sptbn4	IDA		Mouse	PMID:26187182
Cellular Component	GO:0016020	membrane	SPTBN4	IDA		Human	PMID:11086001
Cellular Component	GO:0043025	neuronal cell body	Sptbn4	IDA		Mouse	PMID:20877009
Cellular Component	GO:0033268	node of Ranvier	Sptbn4	IDA		Mouse	MGI:MGI:2181223|PMID:11807096
Cellular Component	GO:0033268	node of Ranvier	Sptbn4	IMP	MGI:MGI:1856134	Mouse	PMID:16687515
Cellular Component	GO:0033268	node of Ranvier	Sptbn4	IDA		Rat	PMID:11086001|RGD:8553353
Cellular Component	GO:0033268	node of Ranvier	Sptbn4	IDA		Rat	PMID:17709431|RGD:14392774
Cellular Component	GO:0016363	nuclear matrix	SPTBN4	IDA		Human	PMID:11294830
Cellular Component	GO:0033270	paranode region of axon	Sptbn4	IDA		Mouse	PMID:20188654
Cellular Component	GO:0005886	plasma membrane	Sptbn4	IDA		Mouse	MGI:MGI:2181223|PMID:11807096
Cellular Component	GO:0016605	PML body	SPTBN4	IDA		Human	PMID:11294830
Cellular Component	GO:0008091	spectrin	SPTBN4	IDA		Human	PMID:11086001
Biological Process	GO:0030534	adult behavior	Sptbn4	IMP	MGI:MGI:3710201	Mouse	PMID:17197442
Biological Process	GO:0030534	adult behavior	Sptbn4	IMP	MGI:MGI:1856939	Mouse	PMID:1634998
Biological Process	GO:0007628	adult walking behavior	Sptbn4	IMP	MGI:MGI:1856939	Mouse	PMID:1634998
Biological Process	GO:0007409	axonogenesis	Sptbn4	IMP	MGI:MGI:1856939	Mouse	PMID:1634998
Biological Process	GO:0061337	cardiac conduction	Sptbn4	IMP	MGI:MGI:1856134	Mouse	PMID:20877009
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	Sptbn4	IMP	MGI:MGI:3710201	Mouse	PMID:17197442
Biological Process	GO:0045162	clustering of voltage-gated sodium channels	Sptbn4	IMP		Mouse	MGI:MGI:2181223|PMID:11807096
Biological Process	GO:0045162	clustering of voltage-gated sodium channels	Sptbn4	IMP	MGI:MGI:3710201	Mouse	PMID:17197442
Biological Process	GO:0009566	fertilization	Sptbn4	IMP	MGI:MGI:1856939	Mouse	PMID:1634998
Biological Process	GO:0010459	negative regulation of heart rate	Sptbn4	IMP	MGI:MGI:1856134	Mouse	PMID:20877009
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Sptbn4	IMP	MGI:MGI:1856939	Mouse	PMID:1634998
Biological Process	GO:0008104	protein localization	Sptbn4	IMP	MGI:MGI:1856134	Mouse	PMID:16687515
Biological Process	GO:0008104	protein localization	Sptbn4	IMP	MGI:MGI:1856134	Mouse	PMID:20877009
Biological Process	GO:0072659	protein localization to plasma membrane	Sptbn4	IMP		Mouse	MGI:MGI:2181223|PMID:11807096
Biological Process	GO:0033135	regulation of peptidyl-serine phosphorylation	Sptbn4	IDA		Mouse	PMID:20877009
Biological Process	GO:0002028	regulation of sodium ion transport	Sptbn4	IMP	MGI:MGI:1856134	Mouse	PMID:20877009
Biological Process	GO:0022414	reproductive process	Sptbn4	IMP	MGI:MGI:3710201	Mouse	PMID:17197442
Biological Process	GO:0007605	sensory perception of sound	Sptbn4	IMP	MGI:MGI:3497744	Mouse	PMID:15381686
Biological Process	GO:0019226	transmission of nerve impulse	Sptbn4	IMP	MGI:MGI:3497744	Mouse	PMID:15381686

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern