Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SPTSSB
  • Mouse genes Sptssb
  • Rat genes Sptssb
  • Zfish genes sptssb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sptssb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SPTSSB	IPI	UniProtKB:O15269	Human	PMID:19416851
Molecular Function	GO:0004758	serine C-palmitoyltransferase activity	SPTSSB	IDA		Human	PMID:19416851
Molecular Function	GO:0004758	serine C-palmitoyltransferase activity	Sptssb	IDA		Mouse	PMID:26438849
Cellular Component	GO:0017059	serine C-palmitoyltransferase complex	SPTSSB	IPI		Human	PMID:19416851
Cellular Component	GO:0017059	serine C-palmitoyltransferase complex	SPTSSB	IDA		Human	PMID:19416851
Cellular Component	GO:0017059	serine C-palmitoyltransferase complex	Sptssb	IDA		Mouse	PMID:26438849
Biological Process	GO:0046513	ceramide biosynthetic process	Sptssb	IMP	MGI:MGI:5689843	Mouse	PMID:26438849
Biological Process	GO:0007029	endoplasmic reticulum organization	Sptssb	IMP	MGI:MGI:5689843	Mouse	PMID:26438849
Biological Process	GO:1904220	regulation of serine C-palmitoyltransferase activity	Sptssb	IMP	MGI:MGI:5689843	Mouse	PMID:26438849
Biological Process	GO:0030148	sphingolipid biosynthetic process	Sptssb	IMP	MGI:MGI:5689843	Mouse	PMID:26438849
Biological Process	GO:0046512	sphingosine biosynthetic process	SPTSSB	IDA		Human	PMID:19416851

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern