Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SRA1
  • Mouse genes Sra1
  • Rat genes Sra1
  • Zfish genes sra1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sra1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Sra1	IDA		Mouse	PMID:15343387
Molecular Function	GO:0016922	nuclear receptor binding	Sra1	IPI	RGD:2147	Rat	PMID:12350225|RGD:628587
Molecular Function	GO:0030374	nuclear receptor coactivator activity	Sra1	IDA		Mouse	PMID:15327771
Molecular Function	GO:0030374	nuclear receptor coactivator activity	Sra1	IDA		Rat	PMID:12350225|RGD:628587
Molecular Function	GO:0005515	protein binding	SRA1	IPI	UniProtKB:Q92769	Human	PMID:20398657
Molecular Function	GO:0005515	protein binding	Sra1	IPI	UniProtKB:P15207	Rat	PMID:12350225|RGD:628587
Molecular Function	GO:0002153	steroid receptor RNA activator RNA binding	SRA1	IDA		Human	PMID:20855289
Molecular Function	GO:0003713	transcription coactivator activity	SRA1	IDA		Human	PMID:10199399
Molecular Function	GO:0003713	transcription coactivator activity	Sra1	IDA		Rat	PMID:12350225|RGD:628587
Cellular Component	GO:0031252	cell leading edge	Sra1	IDA		Mouse	PMID:16831833
Cellular Component	GO:0005737	cytoplasm	SRA1	IDA		Human	PMID:24486609
Cellular Component	GO:0005737	cytoplasm	SRA1	IDA		Human	PMID:27086651
Cellular Component	GO:0005829	cytosol	SRA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045171	intercellular bridge	SRA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0015630	microtubule cytoskeleton	SRA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SRA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SRA1	IDA		Human	PMID:12565891
Cellular Component	GO:0005634	nucleus	SRA1	IDA		Human	PMID:24486609
Cellular Component	GO:0005634	nucleus	SRA1	IDA		Human	PMID:27086651
Cellular Component	GO:0005634	nucleus	Sra1	IDA		Rat	PMID:12350225|RGD:628587
Cellular Component	GO:0005886	plasma membrane	SRA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:1990904	ribonucleoprotein complex	SRA1	IPI	UniProtKB:Q15788	Human	PMID:10199399
Cellular Component	GO:1990904	ribonucleoprotein complex	SRA1	IDA		Human	PMID:20855289
Cellular Component	GO:0031209	SCAR complex	SRA1	IDA		Human	PMID:18560548
Cellular Component	GO:0005667	transcription regulator complex	Sra1	IDA		Mouse	PMID:15327771
Biological Process	GO:0030154	cell differentiation	SRA1	IDA		Human	PMID:14517287
Biological Process	GO:0071391	cellular response to estrogen stimulus	SRA1	IMP		Human	PMID:24486609
Biological Process	GO:0060047	heart contraction	sra1	IMP	ZFIN:ZDB-MRPHLNO-090422-2	Zfish	PMID:19064678
Biological Process	GO:0045662	negative regulation of myoblast differentiation	SRA1	IMP		Human	PMID:20855289
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Sra1	IDA		Mouse	PMID:15327771
Biological Process	GO:0042981	regulation of apoptotic process	SRA1	IDA		Human	PMID:14517287
Biological Process	GO:0007346	regulation of mitotic cell cycle	SRA1	IDA		Human	PMID:14517287

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern