Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SRGN
  • Mouse genes Srgn
  • Rat genes Srgn
  • Zfish genes srgn
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Srgn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005518	collagen binding	Srgn	IDA		Rat	PMID:9207929|RGD:2316806
Molecular Function	GO:0005515	protein binding	SRGN	IPI	UniProtKB:P10144	Human	PMID:11911826
Molecular Function	GO:0005515	protein binding	SRGN	IPI	UniProtKB:O43765	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	SRGN	IPI	UniProtKB:P11226	Human	PMID:21268013
Molecular Function	GO:0005515	protein binding	SRGN	IPI	UniProtKB:O43765	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRGN	IPI	UniProtKB:Q9UMX0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRGN	IPI	UniProtKB:Q9UMX0-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRGN	IPI	UniProtKB:O00623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRGN	IPI	UniProtKB:O43765	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRGN	IPI	UniProtKB:P61601	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRGN	IPI	UniProtKB:Q96EQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRGN	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRGN	IPI	UniProtKB:Q9UMX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Srgn	IPI	UniProtKB:P15379	Mouse	MGI:MGI:3715093|PMID:7535771
Cellular Component	GO:0005615	extracellular space	SRGN	IDA		Human	PMID:11154222
Cellular Component	GO:0098978	glutamatergic synapse	Srgn	IEP		Mouse	PMID:19766573
Cellular Component	GO:0098978	glutamatergic synapse	Srgn	IDA		Mouse	PMID:19766573
Cellular Component	GO:0098978	glutamatergic synapse	Srgn	IDA		Mouse	PMID:27453502
Cellular Component	GO:0098978	glutamatergic synapse	Srgn	IMP		Mouse	PMID:27453502
Cellular Component	GO:0005794	Golgi apparatus	SRGN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	SRGN	IDA		Human	PMID:15136585
Cellular Component	GO:0000139	Golgi membrane	Srgn	IDA		Rat	PMID:12602945|RGD:2316805
Cellular Component	GO:0042629	mast cell granule	Srgn	IDA		Mouse	MGI:MGI:3056870|PMID:15231821
Cellular Component	GO:0099091	postsynaptic specialization, intracellular component	Srgn	IDA		Mouse	PMID:19766573
Cellular Component	GO:0099091	postsynaptic specialization, intracellular component	Srgn	IEP		Mouse	PMID:19766573
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Srgn	IDA		Mouse	PMID:19766573
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Srgn	IEP		Mouse	PMID:19766573
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Srgn	IDA		Mouse	PMID:27453502
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Srgn	IMP		Mouse	PMID:27453502
Cellular Component	GO:0042588	zymogen granule	Srgn	IDA		Rat	PMID:12602945|RGD:2316805
Biological Process	GO:0140507	granzyme-mediated programmed cell death signaling pathway	SRGN	IDA		Human	PMID:11911826
Biological Process	GO:0033382	maintenance of granzyme B location in T cell secretory granule	Srgn	IMP		Mouse	MGI:MGI:3717516|PMID:16046402
Biological Process	GO:0033373	maintenance of protease location in mast cell secretory granule	Srgn	IMP		Mouse	MGI:MGI:3762431|PMID:17010166
Biological Process	GO:0033364	mast cell secretory granule organization	Srgn	IMP		Mouse	MGI:MGI:3056870|PMID:15231821
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Srgn	IDA		Mouse	PMID:27453502
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Srgn	IMP		Mouse	PMID:27453502
Biological Process	GO:0030502	negative regulation of bone mineralization	SRGN	IDA		Human	PMID:16870619
Biological Process	GO:0001818	negative regulation of cytokine production	Srgn	IMP		Mouse	MGI:MGI:3695245|PMID:16807245
Biological Process	GO:0016485	protein processing	Srgn	IDA		Mouse	MGI:MGI:3715689|PMID:17081126
Biological Process	GO:0099175	regulation of postsynapse organization	Srgn	IDA		Mouse	PMID:27453502
Biological Process	GO:0099175	regulation of postsynapse organization	Srgn	IMP		Mouse	PMID:27453502
Biological Process	GO:0033371	T cell secretory granule organization	Srgn	IMP		Mouse	MGI:MGI:3717516|PMID:16046402

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern