Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SRM
  • Mouse genes Srm
  • Rat genes Srm
  • Zfish genes srm
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Srm

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	SRM	IPI	UniProtKB:P19623	Human	PMID:17585781
Molecular Function	GO:0042802	identical protein binding	SRM	IPI	UniProtKB:P19623	Human	PMID:29892012
Molecular Function	GO:0042802	identical protein binding	SRM	IPI	UniProtKB:P19623	Human	PMID:31515488
Molecular Function	GO:0042802	identical protein binding	SRM	IPI	UniProtKB:P19623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRM	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0042803	protein homodimerization activity	SRM	IDA		Human	PMID:17585781
Molecular Function	GO:0004766	spermidine synthase activity	SRM	IDA		Human	PMID:17585781
Molecular Function	GO:0004766	spermidine synthase activity	Srm	IDA		Rat	PMID:12843627|RGD:1359042
Molecular Function	GO:0004766	spermidine synthase activity	Srm	IDA		Rat	PMID:16931179|RGD:7242920
Molecular Function	GO:0004766	spermidine synthase activity	Srm	IMP		Rat	PMID:8494549|RGD:7242928
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Srm	IEP		Mouse	PMID:20439489
Biological Process	GO:0008295	spermidine biosynthetic process	SRM	IDA		Human	PMID:17585781
Biological Process	GO:0008295	spermidine biosynthetic process	Srm	IDA		Rat	PMID:12843627|RGD:1359042
Biological Process	GO:0008295	spermidine biosynthetic process	Srm	IDA		Rat	PMID:16931179|RGD:7242920
Biological Process	GO:0008295	spermidine biosynthetic process	Srm	IMP		Rat	PMID:8494549|RGD:7242928
Biological Process	GO:0008295	spermidine biosynthetic process	srm	IMP	ZFIN:ZDB-GENO-160825-11	Zfish	PMID:27215328

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern