Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SRP54
  • Mouse genes Srp54a
  • Rat genes Srp54a
  • Zfish genes srp54
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Srp54a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008312	7S RNA binding	SRP54	IDA		Human	PMID:18089836
Molecular Function	GO:0008312	7S RNA binding	SRP54	IDA		Human	PMID:9511762
Molecular Function	GO:0030942	endoplasmic reticulum signal peptide binding	SRP54	IDA		Human	PMID:9511762
Molecular Function	GO:0019003	GDP binding	SRP54	IDA		Human	PMID:8622769
Molecular Function	GO:0005525	GTP binding	SRP54	IDA		Human	PMID:8622769
Molecular Function	GO:0003924	GTPase activity	SRP54	IDA		Human	PMID:8247130
Molecular Function	GO:0003924	GTPase activity	SRP54	IMP		Human	PMID:28972538
Molecular Function	GO:0005515	protein binding	SRP54	IPI	UniProtKB:P19712:PRO_0000038050	Human	PMID:24965446
Molecular Function	GO:0043021	ribonucleoprotein complex binding	SRP54	IDA		Human	PMID:9511762
Molecular Function	GO:0003723	RNA binding	SRP54	HDA		Human	PMID:22658674
Cellular Component	GO:0005737	cytoplasm	SRP54	IDA		Human	PMID:10618370
Cellular Component	GO:0005829	cytosol	SRP54	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SRP54	IDA		Human	PMID:18089836
Cellular Component	GO:0005786	signal recognition particle, endoplasmic reticulum targeting	SRP54	IDA		Human	PMID:18089836
Biological Process	GO:0031017	exocrine pancreas development	srp54	IMP	ZFIN:ZDB-MRPHLNO-180405-6	Zfish	PMID:28972538
Biological Process	GO:0031017	exocrine pancreas development	srp54	IMP	ZFIN:ZDB-MRPHLNO-180405-5	Zfish	PMID:28972538
Biological Process	GO:0030851	granulocyte differentiation	SRP54	IMP		Human	PMID:28972538
Biological Process	GO:0030593	neutrophil chemotaxis	srp54	IMP	ZFIN:ZDB-MRPHLNO-180405-5	Zfish	PMID:28972538
Biological Process	GO:0030593	neutrophil chemotaxis	srp54	IMP	ZFIN:ZDB-MRPHLNO-180405-6	Zfish	PMID:28972538
Biological Process	GO:0045047	protein targeting to ER	SRP54	IMP		Human	PMID:18089836

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern