Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SRPK2
  • Mouse genes Srpk2
  • Rat genes Srpk2
  • Zfish genes srpk2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Srpk2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0071889	14-3-3 protein binding	Srpk2	IDA		Mouse	MGI:MGI:5009368|PMID:19592491
Molecular Function	GO:0005524	ATP binding	SRPK2	IDA		Human	PMID:9472028
Molecular Function	GO:0005524	ATP binding	Srpk2	IDA		Mouse	MGI:MGI:1195449|PMID:9446799
Molecular Function	GO:0000287	magnesium ion binding	SRPK2	IDA		Human	PMID:9472028
Molecular Function	GO:0000287	magnesium ion binding	Srpk2	IDA		Mouse	MGI:MGI:1195449|PMID:9446799
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P26368	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P31946	Human	PMID:19592491
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P08621	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q01081	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q14498	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q15287	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q7L014	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q86U06	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q8NAV1	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q8TAD8	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q8WVK2	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q9NWB6	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:O75494	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P07910	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P08621	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P26368	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P31946	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P49761	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P50613	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P62995	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q01081	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q13243	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q13428	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q13595	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q14498	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q15696	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q16629	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q66PJ3	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q7L014	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q86U06	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q8IYB3	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q8NAV1	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q8WVK2	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q8WXA9	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q96MU7	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q9BRL6	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q9BU76	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q9NQ29	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q9NWB6	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q9Y383	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q9Y3Y2	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q9Y5S9	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:D3DU92	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:O15535	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P49760	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P49761	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P51116	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q01081	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q01081-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q08117	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q14498	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q15696	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q8NAV1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q8WVK2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q9P127	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P24928	Human	PMID:28076779
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:O15535	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:O43309	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P17509	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P26368-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P38432	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P51114-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P62995	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P86480	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q05519-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q15287	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q15696	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q5C9Z4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q8TAD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q9BRL6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:O75494	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P08621	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P26368	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P49761	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P50613	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P51116	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P62995	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q13243	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q13428	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q13595	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q14498	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q15287	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q66PJ3	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q7L014	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q8IYB3	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q8NAV1	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q8WXA9	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q96MU7	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q9BU76	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q9NQ29	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q9Y383	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:Q9Y3Y2	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P0DTC9	Human	PMID:32817937
Molecular Function	GO:0005515	protein binding	SRPK2	IPI	UniProtKB:P0DTC9	Human	PMID:34578187
Molecular Function	GO:0005515	protein binding	Srpk2	IPI	UniProtKB:Q07955	Mouse	MGI:MGI:3687681|PMID:10196197
Molecular Function	GO:0004674	protein serine/threonine kinase activity	SRPK2	IGI	UniProtKB:Q15637	Human	PMID:26167880
Molecular Function	GO:0004674	protein serine/threonine kinase activity	SRPK2	IDA		Human	PMID:9472028
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Srpk2	IDA		Mouse	MGI:MGI:1195449|PMID:9446799
Molecular Function	GO:0003723	RNA binding	SRPK2	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	SRPK2	HDA		Human	PMID:22681889
Cellular Component	GO:0000785	chromatin	SRPK2	IDA		Human	PMID:28076779
Cellular Component	GO:0005737	cytoplasm	SRPK2	IDA		Human	PMID:28076779
Cellular Component	GO:0005737	cytoplasm	SRPK2	IDA		Human	PMID:9472028
Cellular Component	GO:0005737	cytoplasm	Srpk2	IDA		Mouse	MGI:MGI:1195449|PMID:9446799
Cellular Component	GO:0005737	cytoplasm	Srpk2	IDA		Mouse	MGI:MGI:5009368|PMID:19592491
Cellular Component	GO:0005829	cytosol	SRPK2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	SRPK2	IDA		Human	PMID:28076779
Cellular Component	GO:0005730	nucleolus	SRPK2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SRPK2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SRPK2	IDA		Human	PMID:28076779
Cellular Component	GO:0005634	nucleus	SRPK2	IDA		Human	PMID:9472028
Cellular Component	GO:0005634	nucleus	Srpk2	IDA		Mouse	MGI:MGI:1195449|PMID:9446799
Biological Process	GO:0001525	angiogenesis	Srpk2	IDA		Mouse	MGI:MGI:5009362|PMID:19906640
Biological Process	GO:0035556	intracellular signal transduction	SRPK2	IDA		Human	PMID:9472028
Biological Process	GO:0035556	intracellular signal transduction	Srpk2	IDA		Mouse	MGI:MGI:1195449|PMID:9446799
Biological Process	GO:0045071	negative regulation of viral genome replication	SRPK2	IDA		Human	PMID:12417631
Biological Process	GO:0035063	nuclear speck organization	Srpk2	IDA		Mouse	MGI:MGI:1195449|PMID:9446799
Biological Process	GO:0018105	peptidyl-serine phosphorylation	SRPK2	IGI	UniProtKB:Q15637	Human	PMID:26167880
Biological Process	GO:0045787	positive regulation of cell cycle	Srpk2	IDA		Mouse	MGI:MGI:5009368|PMID:19592491
Biological Process	GO:0008284	positive regulation of cell population proliferation	SRPK2	IDA		Human	PMID:18559500
Biological Process	GO:0008284	positive regulation of cell population proliferation	Srpk2	IDA		Mouse	MGI:MGI:5009368|PMID:19592491
Biological Process	GO:0010628	positive regulation of gene expression	Srpk2	IDA		Mouse	MGI:MGI:5009368|PMID:19592491
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Srpk2	IDA		Mouse	MGI:MGI:5009368|PMID:19592491
Biological Process	GO:0045070	positive regulation of viral genome replication	SRPK2	IDA		Human	PMID:20498328
Biological Process	GO:0006468	protein phosphorylation	SRPK2	IDA		Human	PMID:9472028
Biological Process	GO:0006468	protein phosphorylation	Srpk2	IDA		Mouse	MGI:MGI:1195449|PMID:9446799
Biological Process	GO:0006468	protein phosphorylation	Srpk2	IDA		Mouse	MGI:MGI:5009368|PMID:19592491
Biological Process	GO:0062176	R-loop processing	SRPK2	IDA		Human	PMID:28076779
Biological Process	GO:0008380	RNA splicing	SRPK2	IDA		Human	PMID:9472028
Biological Process	GO:0008380	RNA splicing	Srpk2	IDA		Mouse	MGI:MGI:1195449|PMID:9446799
Biological Process	GO:0000245	spliceosomal complex assembly	SRPK2	IDA		Human	PMID:9472028
Biological Process	GO:0000245	spliceosomal complex assembly	Srpk2	IDA		Mouse	MGI:MGI:1195449|PMID:9446799

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern