Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SRRM4
  • Mouse genes Srrm4
  • Rat genes Srrm4
  • Zfish genes srrm4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Srrm4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	SRRM4	IPI	UniProtKB:A7MD48	Human	PMID:32296183
Molecular Function	GO:0003729	mRNA binding	Srrm4	IDA		Mouse	MGI:MGI:4414616|PMID:19737518
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:A0A0C4DG62	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:P08621	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:P49756	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:P49759-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:P61964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q01081	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q02040	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q05519-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q14498	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q15287	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q15695	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q15696	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q15973	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q16543	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q32M78	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q6PH81	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q8IYB3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q8IZU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q8TAD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q96EZ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q96IZ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q9BU76	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q9HAZ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q9HBT8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q9P127	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q9Y383	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRRM4	IPI	UniProtKB:Q9Y388	Human	PMID:32296183
Cellular Component	GO:0005634	nucleus	Srrm4	IDA		Mouse	MGI:MGI:4414616|PMID:19737518
Cellular Component	GO:0005684	U2-type spliceosomal complex	srrm4	IDA		Zfish	PMID:30833759
Biological Process	GO:0007409	axonogenesis	srrm4	IMP	ZFIN:ZDB-MRPHLNO-090917-3	Zfish	PMID:19737518
Biological Process	GO:0030154	cell differentiation	Srrm4	IMP		Mouse	MGI:MGI:4414616|PMID:19737518
Biological Process	GO:0030154	cell differentiation	srrm4	IMP		Zfish	PMID:19737518|ZFIN:ZDB-PUB-090914-41
Biological Process	GO:0021754	facial nucleus development	srrm4	IGI	ZFIN:ZDB-GENE-080415-1	Zfish	PMID:25769695
Biological Process	GO:0006397	mRNA processing	Srrm4	IDA		Mouse	MGI:MGI:4414616|PMID:19737518
Biological Process	GO:0006397	mRNA processing	srrm4	IMP		Zfish	PMID:19737518|ZFIN:ZDB-PUB-090914-41
Biological Process	GO:0000398	mRNA splicing, via spliceosome	srrm4	IDA		Zfish	PMID:30833759
Biological Process	GO:0007399	nervous system development	Srrm4	IMP		Mouse	MGI:MGI:4414616|PMID:19737518
Biological Process	GO:0007399	nervous system development	Srrm4	IMP		Mouse	MGI:MGI:5641106|PMID:25838543
Biological Process	GO:0007399	nervous system development	srrm4	IMP		Zfish	PMID:19737518|ZFIN:ZDB-PUB-090914-41
Biological Process	GO:0042551	neuron maturation	srrm4	IGI	ZFIN:ZDB-GENE-080415-1	Zfish	PMID:25769695
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	SRRM4	IDA		Human	PMID:29961578
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	Srrm4	IMP		Mouse	MGI:MGI:6201863|PMID:25727884
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	Srrm4	IMP	MGI:MGI:1856676	Mouse	PMID:23055939
Biological Process	GO:0043484	regulation of RNA splicing	Srrm4	IDA		Mouse	MGI:MGI:4414616|PMID:19737518
Biological Process	GO:0043484	regulation of RNA splicing	srrm4	IMP		Zfish	PMID:19737518|ZFIN:ZDB-PUB-090914-41
Biological Process	GO:0007605	sensory perception of sound	Srrm4	IMP	MGI:MGI:1856676	Mouse	PMID:423972

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern