Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SRSF2
  • Mouse genes Srsf2
  • Rat genes Srsf2
  • Zfish genes srsf2a,srsf2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Srsf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0036002	pre-mRNA binding	Srsf2	IDA		Mouse	PMID:21470964
Molecular Function	GO:0005515	protein binding	SRSF2	IPI	UniProtKB:Q86X95	Human	PMID:15652350
Molecular Function	GO:0005515	protein binding	SRSF2	IPI	UniProtKB:Q01081	Human	PMID:18559666
Molecular Function	GO:0005515	protein binding	SRSF2	IPI	UniProtKB:Q92993	Human	PMID:21157427
Molecular Function	GO:0005515	protein binding	SRSF2	IPI	UniProtKB:Q9H0G5	Human	PMID:21296756
Molecular Function	GO:0005515	protein binding	SRSF2	IPI	UniProtKB:P18583	Human	PMID:21504830
Molecular Function	GO:0005515	protein binding	SRSF2	IPI	UniProtKB:Q01081	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	SRSF2	IPI	UniProtKB:Q15696	Human	PMID:9237760
Molecular Function	GO:0005515	protein binding	SRSF2	IPI	UniProtKB:Q99590	Human	PMID:9447963
Molecular Function	GO:0005515	protein binding	Srsf2	IPI	UniProtKB:P08775|UniProtKB:Q99J95	Mouse	MGI:MGI:5918739|PMID:18641664
Molecular Function	GO:0005515	protein binding	Srsf2	IPI	UniProtKB:P08775|UniProtKB:Q8R409|UniProtKB:Q99J95	Mouse	MGI:MGI:5553217|PMID:23663783
Molecular Function	GO:0005515	protein binding	Srsf2	IPI	UniProtKB:Q91Y44	Mouse	MGI:MGI:5448498|PMID:22570411
Molecular Function	GO:0005515	protein binding	Srsf2	IPI	UniProtKB:P11516	Mouse	PMID:11739632
Molecular Function	GO:0005515	protein binding	Srsf2	IPI	PR:Q61214	Mouse	PMID:21470964
Molecular Function	GO:0005080	protein kinase C binding	Srsf2	IPI	RGD:67383	Rat	PMID:19645017|RGD:11038816
Molecular Function	GO:0003723	RNA binding	SRSF2	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	SRSF2	HDA		Human	PMID:22681889
Cellular Component	GO:0005829	cytosol	SRSF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0035061	interchromatin granule	Srsf2	IDA		Rat	PMID:17123510|RGD:11038817
Cellular Component	GO:0035061	interchromatin granule	Srsf2	IDA		Rat	PMID:19321046|RGD:150429709
Cellular Component	GO:0016607	nuclear speck	SRSF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	SRSF2	IDA		Human	PMID:12799190
Cellular Component	GO:0016607	nuclear speck	SRSF2	IDA		Human	PMID:15798186
Cellular Component	GO:0016607	nuclear speck	SRSF2	IDA		Human	PMID:21984414
Cellular Component	GO:0016607	nuclear speck	SRSF2	IDA		Human	PMID:23562910
Cellular Component	GO:0016607	nuclear speck	Srsf2	IDA		Mouse	PMID:25896510
Cellular Component	GO:0016607	nuclear speck	Srsf2	IDA		Mouse	PMID:15564382
Cellular Component	GO:0016607	nuclear speck	Srsf2	IDA		Mouse	PMID:16376875
Cellular Component	GO:0016607	nuclear speck	Srsf2	IDA		Mouse	PMID:23512658
Cellular Component	GO:0016607	nuclear speck	Srsf2	IDA		Mouse	PMID:20356838
Cellular Component	GO:0016607	nuclear speck	Srsf2	IDA		Mouse	PMID:26013685
Cellular Component	GO:0016607	nuclear speck	Srsf2	IDA		Mouse	PMID:22840402
Cellular Component	GO:0016607	nuclear speck	Srsf2	IDA		Rat	PMID:14657346|RGD:11038801
Cellular Component	GO:0016607	nuclear speck	Srsf2	IDA		Rat	PMID:8408269|RGD:150429667
Cellular Component	GO:0005654	nucleoplasm	SRSF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SRSF2	IDA		Human	PMID:15652350
Cellular Component	GO:0005634	nucleus	SRSF2	IDA		Human	PMID:15988025
Cellular Component	GO:0005634	nucleus	SRSF2	IDA		Human	PMID:17494991
Cellular Component	GO:0005634	nucleus	SRSF2	IDA		Human	PMID:19734146
Cellular Component	GO:0005634	nucleus	SRSF2	IDA		Human	PMID:21653549
Cellular Component	GO:0005634	nucleus	Srsf2	IDA		Mouse	PMID:26013685
Cellular Component	GO:0005634	nucleus	Srsf2	IDA		Mouse	PMID:11739632
Cellular Component	GO:0005634	nucleus	Srsf2	IDA		Mouse	PMID:11641275
Cellular Component	GO:0005726	perichromatin fibrils	Srsf2	IDA		Rat	PMID:19321046|RGD:150429709
Cellular Component	GO:0005681	spliceosomal complex	Srsf2	IDA		Mouse	PMID:11827461
Biological Process	GO:0000278	mitotic cell cycle	Srsf2	IEP		Rat	PMID:14657346|RGD:11038801
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	Srsf2	IDA		Mouse	PMID:21470964
Biological Process	GO:0033197	response to vitamin E	Srsf2	IEP		Rat	PMID:15247049|RGD:11039057

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern