Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SRSF4
  • Mouse genes Srsf4
  • Rat genes Srsf4
  • Zfish genes srsf4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Srsf4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003730	mRNA 3'-UTR binding	srsf4	IDA		Zfish	PMID:31227602
Molecular Function	GO:0005515	protein binding	SRSF4	IPI	UniProtKB:P62995	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	SRSF4	IPI	UniProtKB:P62995	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRSF4	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRSF4	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0003723	RNA binding	SRSF4	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	SRSF4	HDA		Human	PMID:22681889
Molecular Function	GO:1990825	sequence-specific mRNA binding	Srsf4	IDA		Rat	PMID:23233666|RGD:10059618
Cellular Component	GO:0016607	nuclear speck	SRSF4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Srsf4	IDA		Rat	PMID:23233666|RGD:10059618
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Srsf4	IMP		Mouse	PMID:24029230
Biological Process	GO:0048025	negative regulation of mRNA splicing, via spliceosome	SRSF4	IDA		Human	PMID:15009664
Biological Process	GO:0032868	response to insulin	Srsf4	IEP		Rat	PMID:11283022|RGD:11039459

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern