Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SRSF5
  • Mouse genes Srsf5
  • Rat genes Srsf5
  • Zfish genes srsf5a,srsf5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Srsf5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SRSF5	IPI	UniProtKB:Q9BXF3-2	Human	PMID:12762840
Molecular Function	GO:0005515	protein binding	SRSF5	IPI	UniProtKB:P78362	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	SRSF5	IPI	UniProtKB:Q15696	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SRSF5	IPI	UniProtKB:P78362	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Srsf5	IPI	UniProtKB:P83870	Mouse	MGI:MGI:4839441|PMID:18758164
Molecular Function	GO:0005515	protein binding	Srsf5	IPI	UniProtKB:A0A0G2K916,UniProtKB:B2GV38,UniProtKB:B5DFN4,UniProtKB:D3Z941,UniProtKB:D4AA63,UniProtKB:F1M853,UniProtKB:P11250,UniProtKB:P51593,UniProtKB:P61107,UniProtKB:P62718,UniProtKB:P97612,UniProtKB:Q498M4,UniProtKB:Q5PPJ6,UniProtKB:Q5PPK9,UniProtKB:Q63569,UniProtKB:Q6AYJ7	Rat	PMID:27191843|RGD:11344934
Molecular Function	GO:0043422	protein kinase B binding	Srsf5	IPI	RGD:2082	Rat	PMID:15684423|RGD:11039445
Molecular Function	GO:0003723	RNA binding	SRSF5	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	SRSF5	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	Srsf5	IDA		Rat	PMID:9199345|RGD:11039429
Molecular Function	GO:0050733	RS domain binding	Srsf5	IPI	PR:Q9DBU6	Mouse	PMID:15798186
Cellular Component	GO:0005829	cytosol	SRSF5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	Srsf5	IDA		Mouse	MGI:MGI:4839441|PMID:18758164
Cellular Component	GO:0005730	nucleolus	SRSF5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SRSF5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Srsf5	IDA		Rat	PMID:23233666|RGD:10059618
Biological Process	GO:0032869	cellular response to insulin stimulus	Srsf5	IEP		Rat	PMID:7686911|RGD:729792
Biological Process	GO:0001889	liver development	Srsf5	IEP		Rat	PMID:9199345|RGD:11039429
Biological Process	GO:0097421	liver regeneration	Srsf5	IEP		Rat	PMID:7686911|RGD:729792
Biological Process	GO:0033120	positive regulation of RNA splicing	Srsf5	IMP		Rat	PMID:9199345|RGD:11039429
Biological Process	GO:0051726	regulation of cell cycle	Srsf5	IEP		Rat	PMID:7686911|RGD:729792
Biological Process	GO:0032868	response to insulin	Srsf5	IEP		Rat	PMID:11283022|RGD:11039459
Biological Process	GO:0032868	response to insulin	Srsf5	IDA		Rat	PMID:15684423|RGD:11039445
Biological Process	GO:0009611	response to wounding	Srsf5	IDA		Mouse	PMID:9857059

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern