Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SSH1
  • Mouse genes Ssh1
  • Rat genes Ssh1
  • Zfish genes ssh1a,ssh1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ssh1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	SSH1	IDA		Human	PMID:11832213
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	SSH1	IDA		Human	PMID:11832213
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	SSH1	IMP		Human	PMID:19000834
Molecular Function	GO:0005515	protein binding	SSH1	IPI	UniProtKB:P31946	Human	PMID:15159416
Molecular Function	GO:0005515	protein binding	SSH1	IPI	UniProtKB:P27348	Human	PMID:15660133
Molecular Function	GO:0005515	protein binding	SSH1	IPI	UniProtKB:P53667	Human	PMID:15660133
Molecular Function	GO:0005515	protein binding	SSH1	IPI	UniProtKB:Q9BR76	Human	PMID:17350576
Molecular Function	GO:0005515	protein binding	SSH1	IPI	UniProtKB:P31946	Human	PMID:19329994
Molecular Function	GO:0005515	protein binding	SSH1	IPI	UniProtKB:P27348	Human	PMID:19371722
Molecular Function	GO:0005515	protein binding	SSH1	IPI	UniProtKB:P23528	Human	PMID:21525957
Cellular Component	GO:0031252	cell leading edge	Ssh1	IDA		Rat	PMID:22496574|RGD:11535117
Cellular Component	GO:0042995	cell projection	Ssh1	IDA		Rat	PMID:22496574|RGD:11535117
Cellular Component	GO:0005737	cytoplasm	SSH1	IDA		Human	PMID:14645219
Cellular Component	GO:0005829	cytosol	Ssh1	IDA		Rat	PMID:22496574|RGD:11535117
Cellular Component	GO:0030426	growth cone	Ssh1	IDA		Rat	PMID:15660133|RGD:11535125
Cellular Component	GO:0005886	plasma membrane	SSH1	IDA		Human	PMID:14645219
Biological Process	GO:0030036	actin cytoskeleton organization	SSH1	IMP		Human	PMID:11832213
Biological Process	GO:0000902	cell morphogenesis	SSH1	IMP		Human	PMID:14645219
Biological Process	GO:0071318	cellular response to ATP	SSH1	IDA		Human	PMID:19000834
Biological Process	GO:0098976	excitatory chemical synaptic transmission	Ssh1	IMP		Rat	PMID:20442266|RGD:11535133
Biological Process	GO:1904719	positive regulation of AMPA glutamate receptor clustering	Ssh1	IMP		Rat	PMID:20442266|RGD:11535133
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	Ssh1	IMP		Rat	PMID:20442266|RGD:11535133
Biological Process	GO:1901216	positive regulation of neuron death	Ssh1	IMP		Rat	PMID:22117609|RGD:11535134
Biological Process	GO:0031915	positive regulation of synaptic plasticity	Ssh1	IMP		Rat	PMID:20442266|RGD:11535133
Biological Process	GO:1904754	positive regulation of vascular associated smooth muscle cell migration	Ssh1	IMP		Rat	PMID:21868701|RGD:11535005
Biological Process	GO:0006470	protein dephosphorylation	SSH1	IMP		Human	PMID:11832213
Biological Process	GO:0006470	protein dephosphorylation	SSH1	IMP		Human	PMID:14645219
Biological Process	GO:0051246	regulation of protein metabolic process	SSH1	IDA		Human	PMID:19000834

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern