Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SSTR2
  • Mouse genes Sstr2
  • Rat genes Sstr2
  • Zfish genes sstr2a,sstr2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sstr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030165	PDZ domain binding	SSTR2	IPI	UniProtKB:Q9Y566	Human	PMID:10551867
Molecular Function	GO:0030165	PDZ domain binding	Sstr2	IPI	UniProtKB:Q9WV48	Rat	PMID:10551867|RGD:8554584
Molecular Function	GO:0005515	protein binding	SSTR2	IPI	UniProtKB:Q9Y566	Human	PMID:10551867
Molecular Function	GO:0005515	protein binding	SSTR2	IPI	UniProtKB:P27986	Human	PMID:16917505
Molecular Function	GO:0005515	protein binding	SSTR2	IPI	UniProtKB:P35346	Human	PMID:18653781
Molecular Function	GO:0005515	protein binding	SSTR2	IPI	UniProtKB:P32745	Human	PMID:22651821
Molecular Function	GO:0004994	somatostatin receptor activity	Sstr2	IMP		Mouse	PMID:7929134
Molecular Function	GO:0004994	somatostatin receptor activity	Sstr2	IDA		Mouse	PMID:7929134
Molecular Function	GO:0004994	somatostatin receptor activity	Sstr2	IDA		Mouse	PMID:1346068
Molecular Function	GO:0004994	somatostatin receptor activity	Sstr2	IDA		Rat	PMID:1374909|RGD:70025
Cellular Component	GO:0005737	cytoplasm	Sstr2	IDA		Rat	PMID:9322965|RGD:2325006
Cellular Component	GO:0005829	cytosol	SSTR2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Sstr2	IDA		Mouse	PMID:7929134
Cellular Component	GO:0005886	plasma membrane	Sstr2	IDA		Mouse	PMID:9166719
Cellular Component	GO:0005886	plasma membrane	Sstr2	IDA		Rat	PMID:9322965|RGD:2325006
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	Sstr2	IDA		Mouse	PMID:9166719
Biological Process	GO:0071392	cellular response to estradiol stimulus	Sstr2	IEP		Rat	PMID:9564833|RGD:2325004
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	Sstr2	IEP		Rat	PMID:14512709|RGD:2325001
Biological Process	GO:0021549	cerebellum development	Sstr2	IEP		Rat	PMID:9166718|RGD:2325007
Biological Process	GO:0030900	forebrain development	Sstr2	IEP		Rat	PMID:10805921|RGD:2325003
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Sstr2	IMP		Mouse	PMID:7929134
Biological Process	GO:0007218	neuropeptide signaling pathway	Sstr2	IDA		Mouse	PMID:9166719
Biological Process	GO:0030432	peristalsis	Sstr2	IMP		Rat	PMID:12504886|RGD:727490
Biological Process	GO:0006937	regulation of muscle contraction	Sstr2	IMP		Rat	PMID:11897621|RGD:737668
Biological Process	GO:0042594	response to starvation	Sstr2	IEP		Rat	PMID:7956902|RGD:2325008
Biological Process	GO:0007283	spermatogenesis	Sstr2	IEP		Rat	PMID:9421433|RGD:2325005

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern