Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SSTR4
  • Mouse genes Sstr4
  • Rat genes Sstr4
  • Zfish genes sstr1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sstr4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SSTR4	IPI	UniProtKB:P35346	Human	PMID:19426801
Molecular Function	GO:0005515	protein binding	Sstr4	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:3764767|PMID:17950729
Molecular Function	GO:0005515	protein binding	Sstr4	IPI	RGD:68424	Rat	PMID:17950729|RGD:2324997
Molecular Function	GO:0005515	protein binding	Sstr4	IPI	UniProtKB:P31016	Rat	PMID:17950729|RGD:2324997
Molecular Function	GO:0004994	somatostatin receptor activity	Sstr4	IDA		Rat	PMID:1362243|RGD:727545
Cellular Component	GO:0005737	cytoplasm	Sstr4	IDA		Rat	PMID:9322965|RGD:2325006
Cellular Component	GO:0005886	plasma membrane	Sstr4	IDA		Rat	PMID:9322965|RGD:2325006
Biological Process	GO:0016477	cell migration	Sstr4	IMP		Rat	PMID:16534498|RGD:2324999
Biological Process	GO:0016477	cell migration	Sstr4	IDA		Rat	PMID:17945410|RGD:2324998
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	Sstr4	IEP		Rat	PMID:14512709|RGD:2325001
Biological Process	GO:0030900	forebrain development	Sstr4	IEP		Rat	PMID:10805921|RGD:2325003
Biological Process	GO:0106072	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	Sstr4	IDA		Rat	PMID:8175684|RGD:2325010
Biological Process	GO:0090238	positive regulation of arachidonic acid secretion	Sstr4	IDA		Rat	PMID:8175684|RGD:2325010
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Sstr4	IDA		Rat	PMID:8175684|RGD:2325010

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern