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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
 Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Star

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Star
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0015485cholesterol bindingSTARIDAHumanPMID:18403318
Molecular FunctionGO:0005515protein bindingSTARIPIUniProtKB:P43364-2HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTARIPIUniProtKB:G5E962HumanPMID:25910212
Molecular FunctionGO:0005515protein bindingSTARIPIUniProtKB:P43364HumanPMID:26871637
Molecular FunctionGO:0005515protein bindingSTARIPIUniProtKB:O60906HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTARIPIUniProtKB:P43364HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTARIPIUniProtKB:Q15276HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTARIPIUniProtKB:Q6RW13-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTARIPIUniProtKB:Q6ZPD8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTARIPIUniProtKB:Q8IZR5-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTARIPIUniProtKB:Q9UNK0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTARIPIUniProtKB:P42858HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingStarIPIRGD:3010RatPMID:12925534|RGD:1600085
Cellular ComponentGO:0005829cytosolStarIDARatPMID:12892842|RGD:1600086
Cellular ComponentGO:0030061mitochondrial cristaStarIDARatPMID:9065457|RGD:4889558
Cellular ComponentGO:0005758mitochondrial intermembrane spaceStarIDARatPMID:7588255|RGD:1600079
Cellular ComponentGO:0005739mitochondrionStarHDAMousePMID:18614015
Cellular ComponentGO:0005739mitochondrionStarHDAMousePMID:14651853
Cellular ComponentGO:0005739mitochondrionStarIDAMousePMID:7961770
Cellular ComponentGO:0043005neuron projectionStarIDARatPMID:19730783|RGD:4145616
Cellular ComponentGO:0043025neuronal cell bodyStarIDARatPMID:19730783|RGD:4145616
Biological ProcessGO:0006699bile acid biosynthetic processStarIDARatPMID:15382124|RGD:1600081
Biological ProcessGO:0018879biphenyl metabolic processStarIEPRatPMID:19071209|RGD:4768197
Biological ProcessGO:0007420brain developmentStarIEPRatPMID:14511326|RGD:1600084
Biological ProcessGO:0044255cellular lipid metabolic processStarIMPMGI:MGI:2388706MousePMID:9326645
Biological ProcessGO:0071312cellular response to alkaloidStarIEPRatPMID:19639602|RGD:4145624
Biological ProcessGO:0071236cellular response to antibioticStarIEPRatPMID:18655822|RGD:4777466
Biological ProcessGO:0071276cellular response to cadmium ionStarIEPRatPMID:17719163|RGD:4835171
Biological ProcessGO:0071320cellular response to cAMPStarIEPRatPMID:9832418|RGD:4145594
Biological ProcessGO:0071549cellular response to dexamethasone stimulusStarIEPRatPMID:20075416|RGD:4145599
Biological ProcessGO:0071872cellular response to epinephrine stimulusStarIEPRatPMID:11064152|RGD:4145763
Biological ProcessGO:0044344cellular response to fibroblast growth factor stimulusStarIEPRatPMID:17494997|RGD:2289861
Biological ProcessGO:0044344cellular response to fibroblast growth factor stimulusStarIEPRatPMID:19814654|RGD:4145611
Biological ProcessGO:0071372cellular response to follicle-stimulating hormone stimulusStarIEPRatPMID:20810564|RGD:4145531
Biological ProcessGO:0071333cellular response to glucose stimulusStarIEPRatPMID:18353182|RGD:4785271
Biological ProcessGO:0071371cellular response to gonadotropin stimulusStarIEPRatPMID:11172811|RGD:4145716
Biological ProcessGO:0071378cellular response to growth hormone stimulusStarIEPRatPMID:10098503|RGD:4891987
Biological ProcessGO:0032869cellular response to insulin stimulusStarIEPRatPMID:17023532|RGD:1600072
Biological ProcessGO:0035457cellular response to interferon-alphaStarIMPRatPMID:19929576|RGD:4145607
Biological ProcessGO:0071222cellular response to lipopolysaccharideStarIEPRatPMID:20665543|RGD:4145535
Biological ProcessGO:0071373cellular response to luteinizing hormone stimulusStarIEPRatPMID:17241129|RGD:1600071
Biological ProcessGO:0071248cellular response to metal ionStarIEPRatPMID:18602937|RGD:4890967
Biological ProcessGO:0071407cellular response to organic cyclic compoundStarIEPRatPMID:20937274|RGD:4145529
Biological ProcessGO:0071560cellular response to transforming growth factor beta stimulusStarIEPRatPMID:18511507|RGD:4781450
Biological ProcessGO:0071346cellular response to type II interferonStarIEPRatPMID:9564825|RGD:4891971
Biological ProcessGO:0007623circadian rhythmStarIEPRatPMID:19190255|RGD:4145635
Biological ProcessGO:0042747circadian sleep/wake cycle, REM sleepStarIEPRatPMID:12597996|RGD:4891963
Biological ProcessGO:0018894dibenzo-p-dioxin metabolic processStarIEPRatPMID:18637154|RGD:4778755
Biological ProcessGO:0016101diterpenoid metabolic processStarIEPRatPMID:11064152|RGD:4145763
Biological ProcessGO:0006703estrogen biosynthetic processStarIMPRatPMID:16579833|RGD:1600078
Biological ProcessGO:0008211glucocorticoid metabolic processStarIMPMGI:MGI:2388706MousePMID:9326645
Biological ProcessGO:0017143insecticide metabolic processStarIEPRatPMID:18401575|RGD:4890969
Biological ProcessGO:0032367intracellular cholesterol transportStarIEPRatPMID:14617579|RGD:4145640
Biological ProcessGO:0008584male gonad developmentStarIEPRatPMID:18772241|RGD:2303053
Biological ProcessGO:0043524negative regulation of neuron apoptotic processStarIMPRatPMID:16579833|RGD:1600078
Biological ProcessGO:0001556oocyte maturationstarIMPZFIN:ZDB-GENO-201007-6ZfishPMID:31322169
Biological ProcessGO:0006082organic acid metabolic processStarIEPRatPMID:17400581|RGD:4889129
Biological ProcessGO:0018958phenol-containing compound metabolic processStarIEPRatPMID:18191889|RGD:4831838
Biological ProcessGO:0018963phthalate metabolic processStarIEPRatPMID:16809437|RGD:1601046
Biological ProcessGO:0070859positive regulation of bile acid biosynthetic processSTARIDAHumanPMID:18403318
Biological ProcessGO:0010628positive regulation of gene expressionStarIMPRatPMID:19156851|RGD:4145636
Biological ProcessGO:0050769positive regulation of neurogenesisStarIMPRatPMID:16579833|RGD:1600078
Biological ProcessGO:0048168regulation of neuronal synaptic plasticityStarIMPRatPMID:16673174|RGD:1600077
Biological ProcessGO:0050810regulation of steroid biosynthetic processStarIDAMousePMID:7961770
Biological ProcessGO:0014823response to activityStarIEPRatPMID:20393161|RGD:4145597
Biological ProcessGO:0046677response to antibioticStarIEPRatPMID:19118620|RGD:4763313
Biological ProcessGO:0080021response to benzoic acidStarIEPRatPMID:30476341|RGD:151893502
Biological ProcessGO:0051412response to corticosteroneStarIEPRatPMID:18335507|RGD:4831835
Biological ProcessGO:0043627response to estrogenStarIEPRatPMID:19734697|RGD:4145613
Biological ProcessGO:0045471response to ethanolStarIEPRatPMID:16930210|RGD:1600073
Biological ProcessGO:0045471response to ethanolStarIEPRatPMID:20633208|RGD:4145537
Biological ProcessGO:0060992response to fungicideStarIEPRatPMID:16214947|RGD:4889136
Biological ProcessGO:0034698response to gonadotropinStarIEPRatPMID:19929576|RGD:4145607
Biological ProcessGO:0009635response to herbicideStarIEPRatPMID:20667998|RGD:4145533
Biological ProcessGO:0042542response to hydrogen peroxideStarIEPRatPMID:14635199|RGD:1599711
Biological ProcessGO:0017085response to insecticideStarIEPRatPMID:19892000|RGD:4145608
Biological ProcessGO:0010212response to ionizing radiationStarIEPRatPMID:18821396|RGD:4770368
Biological ProcessGO:0010288response to lead ionStarIEPRatPMID:14514953|RGD:1600082
Biological ProcessGO:0044321response to leptinStarIEPRatPMID:11604238|RGD:4145667
Biological ProcessGO:0035094response to nicotineStarIEPRatPMID:20498001|RGD:4145595
Biological ProcessGO:0007584response to nutrientStarIEPRatPMID:16882930|RGD:1600074
Biological ProcessGO:0031667response to nutrient levelsStarIEPRatPMID:19190255|RGD:4145635
Biological ProcessGO:0014070response to organic cyclic compoundStarIEPRatPMID:16737795|RGD:1600076
Biological ProcessGO:0014070response to organic cyclic compoundStarIEPRatPMID:22777679|RGD:151893504
Biological ProcessGO:0014070response to organic cyclic compoundStarIEPRatPMID:28208728|RGD:151893505
Biological ProcessGO:0010033response to organic substanceStarIEPRatPMID:18804513|RGD:4772578
Biological ProcessGO:0043434response to peptide hormoneStarIEPRatPMID:18609294|RGD:4781133
Biological ProcessGO:0032526response to retinoic acidStarHEPRatPMID:30329139|RGD:151893506
Biological ProcessGO:0032526response to retinoic acidStarIEPRatPMID:30476341|RGD:151893502
Biological ProcessGO:0048545response to steroid hormoneStarIEPRatPMID:19961867|RGD:4145605
Biological ProcessGO:0009636response to toxic substanceStarIEPRatPMID:20610472|RGD:4145538
Biological ProcessGO:0009410response to xenobiotic stimulusStarIEPRatPMID:16777379|RGD:1600075
Biological ProcessGO:0061370testosterone biosynthetic processStarIEPRatPMID:19883722|RGD:4145609

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory