Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STARD4
  • Mouse genes Stard4
  • Rat genes Stard4
  • Zfish genes stard4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stard4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015485	cholesterol binding	STARD4	IDA		Human	PMID:18403318
Molecular Function	GO:0120020	cholesterol transfer activity	STARD4	IDA		Human	PMID:18403318
Molecular Function	GO:0005515	protein binding	STARD4	IPI	UniProtKB:P08247	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STARD4	IPI	UniProtKB:Q15041	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STARD4	IPI	UniProtKB:Q6RW13-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STARD4	IPI	UniProtKB:Q8TB36	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STARD4	IPI	UniProtKB:Q8TD31-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STARD4	IPI	UniProtKB:Q9H2K0	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	STARD4	IDA		Human	PMID:21767660
Cellular Component	GO:0031410	cytoplasmic vesicle	STARD4	IDA		Human	PMID:21767660
Cellular Component	GO:0005829	cytosol	Stard4	IDA		Mouse	MGI:MGI:5295922|PMID:21767660
Cellular Component	GO:0005783	endoplasmic reticulum	Stard4	IDA		Mouse	MGI:MGI:5295922|PMID:21767660
Biological Process	GO:0070508	cholesterol import	STARD4	IDA		Human	PMID:18403318
Biological Process	GO:0010879	cholesterol transport involved in cholesterol storage	STARD4	IDA		Human	PMID:18403318
Biological Process	GO:0032367	intracellular cholesterol transport	STARD4	IDA		Human	PMID:18403318
Biological Process	GO:0070859	positive regulation of bile acid biosynthetic process	STARD4	IDA		Human	PMID:18403318
Biological Process	GO:0090205	positive regulation of cholesterol metabolic process	STARD4	IDA		Human	PMID:18403318

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern