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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Stat3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stat3
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0031730CCR5 chemokine receptor bindingStat3IPIRGD:620596RatPMID:14674010|RGD:1582346
Molecular FunctionGO:0031490chromatin DNA bindingSTAT3IDAHumanPMID:17344214
Molecular FunctionGO:0003677DNA bindingStat3IDAMousePMID:15096606
Molecular FunctionGO:0003677DNA bindingStat3IDAMousePMID:15659653
Molecular FunctionGO:0003677DNA bindingStat3IDAMousePMID:11579100
Molecular FunctionGO:0003677DNA bindingStat3IDAMousePMID:12746441
Molecular FunctionGO:0003677DNA bindingStat3IDARatPMID:8530402|RGD:730023
Molecular FunctionGO:0001228DNA-binding transcription activator activity, RNA polymerase II-specificSTAT3IDAHumanPMID:16835372
Molecular FunctionGO:0001228DNA-binding transcription activator activity, RNA polymerase II-specificSTAT3IMPHumanPMID:16946298
Molecular FunctionGO:0001228DNA-binding transcription activator activity, RNA polymerase II-specificSTAT3IGIRNAcentral:URS00004E0808_9606,UniProtKB:P05231HumanPMID:31886314
Molecular FunctionGO:0003700DNA-binding transcription factor activitySTAT3IDAHumanPMID:17344214
Molecular FunctionGO:0003700DNA-binding transcription factor activitySTAT3IDAHumanPMID:28781374
Molecular FunctionGO:0003700DNA-binding transcription factor activitySTAT3IDAHumanPMID:7568001
Molecular FunctionGO:0003700DNA-binding transcription factor activitySTAT3IDAHumanPMID:9535918
Molecular FunctionGO:0003700DNA-binding transcription factor activityStat3IMPMouseMGI:MGI:5825383|PMID:28065600
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificSTAT3IDAHumanPMID:17344214
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificStat3IDAMousePMID:26026268
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificStat3IDAMousePMID:27830702
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificStat3IDAMousePMID:15096606
Molecular FunctionGO:0140297DNA-binding transcription factor bindingSTAT3IPIUniProtKB:P49715HumanPMID:15664994
Molecular FunctionGO:0140297DNA-binding transcription factor bindingStat3IPIRGD:3774RatPMID:16527988|RGD:1601384
Molecular FunctionGO:0042802identical protein bindingSTAT3IPIUniProtKB:P40763HumanPMID:17676033
Molecular FunctionGO:0042802identical protein bindingSTAT3IPIUniProtKB:P40763HumanPMID:21988832
Molecular FunctionGO:0042802identical protein bindingSTAT3IPIUniProtKB:P40763HumanPMID:25609649
Molecular FunctionGO:0042802identical protein bindingSTAT3IPIUniProtKB:P40763HumanPMID:7510216
Molecular FunctionGO:0042802identical protein bindingStat3IPIUniProtKB:P42227MouseMGI:MGI:5916841|PMID:23434585
Molecular FunctionGO:0042802identical protein bindingStat3IPIUniProtKB:P42227MouseMGI:MGI:6093001|PMID:17463090
Molecular FunctionGO:0140677molecular function activator activitySTAT3IDAHumanPMID:17344214
Molecular FunctionGO:0035259nuclear glucocorticoid receptor bindingStat3IPIRGD:2741RatPMID:20155810|RGD:4892121
Molecular FunctionGO:0004879nuclear receptor activitySTAT3IDAHumanPMID:17324931
Molecular FunctionGO:0070878primary miRNA bindingSTAT3IGIUniProtKB:P05231HumanPMID:31507089
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P51813HumanPMID:10688651
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P07949HumanPMID:11536047
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q07666HumanPMID:11585385
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P04626HumanPMID:11940572
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P18031HumanPMID:11970898
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q9P0J0HumanPMID:12867595
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P00533HumanPMID:14966128
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P50750HumanPMID:15286705
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P00533HumanPMID:15657067
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:O43318HumanPMID:15764709
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P18031HumanPMID:15821101
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P08069HumanPMID:15998644
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P04626HumanPMID:16273093
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P20749HumanPMID:16306601
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q9UER7HumanPMID:16331268
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q9DUM3HumanPMID:16364321
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q96EY1-1HumanPMID:16531398
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q13882HumanPMID:16568091
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q8TAE8HumanPMID:18200042
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q9Y2Y0HumanPMID:18234692
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P30626HumanPMID:18330356
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q04206HumanPMID:19345327
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P04626HumanPMID:19372587
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P43405HumanPMID:20133729
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:O15392HumanPMID:20826784
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P45984HumanPMID:20871632
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P45984-1HumanPMID:20871632
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P04626HumanPMID:20876300
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P06401HumanPMID:20876300
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:O00570HumanPMID:20929579
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P06401HumanPMID:21184768
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P08047HumanPMID:21184768
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P43405HumanPMID:21516116
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:O95661HumanPMID:21643014
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q14938-3HumanPMID:21953450
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q14938-4HumanPMID:21953450
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:O14874HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P07384HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P22736HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P30626HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P31146HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P46781HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q06520HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q13011HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q8TE76HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q92665HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q96G01HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q9BVP2HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q9ULD0HumanPMID:21988832
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P30084HumanPMID:23416296
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q15910HumanPMID:23684459
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P00533HumanPMID:24135280
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q98PK8HumanPMID:24172987
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P00533HumanPMID:24189400
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P08047HumanPMID:24396070
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P00533HumanPMID:24658140
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P23458HumanPMID:25065853
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P00533HumanPMID:25241761
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P07949HumanPMID:25241761
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P42224HumanPMID:25241761
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P32119HumanPMID:25402766
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P25791HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P43405HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P51451HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P51813HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q8TAE8HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q9Y2H2HumanPMID:25476455
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P42224HumanPMID:25609649
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P51813HumanPMID:25814554
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q09472HumanPMID:26504087
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P42224HumanPMID:26966684
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P58215HumanPMID:28065600
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P51451HumanPMID:29892012
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:O75116HumanPMID:30413785
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P43405HumanPMID:31515488
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P51451HumanPMID:31515488
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P51813HumanPMID:31515488
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P35232HumanPMID:31899195
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P00533HumanPMID:31980649
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P12268HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P43405HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P51451HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P51813HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q96HA1-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:O15264HumanPMID:32852592
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q16236HumanPMID:32911434
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P42224HumanPMID:35140242
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:P42224HumanPMID:8662591
Molecular FunctionGO:0005515protein bindingSTAT3IPIUniProtKB:Q99062HumanPMID:9864141
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:P23927MouseMGI:MGI:6114831|PMID:27724964
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:P30084MouseMGI:MGI:5512929|PMID:23416296
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:Q8TAE8MouseMGI:MGI:4420897|PMID:18200042
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:Q9CRD0MouseMGI:MGI:5908327|PMID:23972987
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:O35387|UniProtKB:Q80VH0MouseMGI:MGI:3688344|PMID:15102471
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:P23927MouseMGI:MGI:3688344|PMID:15102471
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:Q64221MouseMGI:MGI:3795052|PMID:18356286
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:P35428|UniProtKB:P70120MouseMGI:MGI:5284803|PMID:15156153
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:O54714MouseMGI:MGI:5294492|PMID:21812053
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:P70424|UniProtKB:Q00175MouseMGI:MGI:5437426|PMID:20876300
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:Q64261MouseMGI:MGI:5514446|PMID:23948297
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:Q9NRF2MouseMGI:MGI:5644006|PMID:24396070
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:Q9D385MouseMGI:MGI:3774679|PMID:18234692
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:P40189MouseMGI:MGI:4441144|PMID:10982829
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:Q00175MouseMGI:MGI:5437422|PMID:21184768
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:P48025MouseMGI:MGI:5915342|PMID:20133729
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:P40189MouseMGI:MGI:5508316|PMID:8662591
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:O54784MouseMGI:MGI:3610586|PMID:16219639
Molecular FunctionGO:0005515protein bindingStat3IPIPR:Q91WG4MousePMID:10954736
Molecular FunctionGO:0005515protein bindingStat3IPIPR:Q60793MousePMID:24129709
Molecular FunctionGO:0005515protein bindingStat3IPIPR:Q9JHI9MousePMID:20530874
Molecular FunctionGO:0005515protein bindingStat3IPIPR:P70451MousePMID:12738762
Molecular FunctionGO:0005515protein bindingStat3IPIPR:P61372MousePMID:15659653
Molecular FunctionGO:0005515protein bindingStat3IPIMGI:MGI:96628MousePMID:15659653
Molecular FunctionGO:0005515protein bindingStat3IPIPR:Q08481MousePMID:11254359
Molecular FunctionGO:0005515protein bindingStat3IPIPR:Q3ZN08MousePMID:26026268
Molecular FunctionGO:0005515protein bindingStat3IPIPR:Q8JZL0MousePMID:12426389
Molecular FunctionGO:0005515protein bindingStat3IPIPR:P61809MousePMID:15096606
Molecular FunctionGO:0005515protein bindingStat3IPIPR:Q06180MousePMID:26026268
Molecular FunctionGO:0005515protein bindingStat3IPIPR:P49615MousePMID:15096606
Molecular FunctionGO:0005515protein bindingStat3IPIPR:P20293MousePMID:16801560
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:Q6RUV5RatPMID:16055727|RGD:13792550
Molecular FunctionGO:0005515protein bindingStat3IPIUniProtKB:O13097RatPMID:17954917|RGD:13432315
Molecular FunctionGO:0046983protein dimerization activityStat3IPIPR:P42227MousePMID:11579100
Molecular FunctionGO:0046983protein dimerization activityStat3IPIPR:P42225MousePMID:11579100
Molecular FunctionGO:0042803protein homodimerization activityStat3IDAMouseMGI:MGI:5825383|PMID:28065600
Molecular FunctionGO:0019901protein kinase bindingStat3IPIUniProtKB:O54949MouseMGI:MGI:3843436|PMID:15004007
Molecular FunctionGO:0019903protein phosphatase bindingSTAT3IPIUniProtKB:P17706-2HumanPMID:12359225
Molecular FunctionGO:0019903protein phosphatase bindingSTAT3IPIUniProtKB:O14522HumanPMID:17360477
Molecular FunctionGO:0000978RNA polymerase II cis-regulatory region sequence-specific DNA bindingSTAT3IDAHumanPMID:19390056
Molecular FunctionGO:0061629RNA polymerase II-specific DNA-binding transcription factor bindingSTAT3IPIUniProtKB:Q96ST3HumanPMID:22783022
Molecular FunctionGO:0061629RNA polymerase II-specific DNA-binding transcription factor bindingSTAT3IPIUniProtKB:P17947HumanPMID:24429361
Molecular FunctionGO:0061629RNA polymerase II-specific DNA-binding transcription factor bindingSTAT3IPIUniProtKB:P49715HumanPMID:24429361
Molecular FunctionGO:0061629RNA polymerase II-specific DNA-binding transcription factor bindingSTAT3IPIUniProtKB:P37231HumanPMID:28467929
Molecular FunctionGO:0043565sequence-specific DNA bindingStat3IDAMousePMID:16801560
Molecular FunctionGO:0043565sequence-specific DNA bindingStat3IDARatPMID:16648019|RGD:2298581
Molecular FunctionGO:0035591signaling adaptor activitySTAT3IPIUniProtKB:P43405HumanPMID:31145836
Molecular FunctionGO:0005102signaling receptor bindingSTAT3IPIUniProtKB:P40189HumanPMID:31145836
Molecular FunctionGO:0000976transcription cis-regulatory region bindingSTAT3IDAHumanPMID:17324931
Cellular ComponentGO:0000785chromatinSTAT3IDAHumanPMID:16835372
Cellular ComponentGO:0005737cytoplasmSTAT3IDAHumanPMID:17360477
Cellular ComponentGO:0005737cytoplasmSTAT3IDAHumanPMID:18234692
Cellular ComponentGO:0005737cytoplasmSTAT3IDAHumanPMID:22783022
Cellular ComponentGO:0005737cytoplasmSTAT3IDAHumanPMID:31899195
Cellular ComponentGO:0005737cytoplasmStat3IDAMouseMGI:MGI:5284803|PMID:15156153
Cellular ComponentGO:0005737cytoplasmStat3IDAMouseMGI:MGI:5448485|PMID:22761423
Cellular ComponentGO:0005737cytoplasmStat3IDAMouseMGI:MGI:4889014|PMID:21234744
Cellular ComponentGO:0005737cytoplasmStat3IDAMousePMID:19796622
Cellular ComponentGO:0005737cytoplasmStat3IDAMousePMID:12746441
Cellular ComponentGO:0005737cytoplasmStat3IDAMousePMID:15749075
Cellular ComponentGO:0005737cytoplasmStat3IDAMousePMID:12634107
Cellular ComponentGO:0005737cytoplasmStat3IDAMousePMID:15096606
Cellular ComponentGO:0005737cytoplasmStat3IDARatPMID:17353091|RGD:2291924
Cellular ComponentGO:0005829cytosolSTAT3IDAHumanGO_REF:0000052
Cellular ComponentGO:0098978glutamatergic synapseStat3EXPRatPMID:22284190|RGD:13702421
Cellular ComponentGO:0098978glutamatergic synapseStat3IDARatPMID:22284190|RGD:13702421
Cellular ComponentGO:0098978glutamatergic synapseStat3IMPRatPMID:22284190|RGD:13702421
Cellular ComponentGO:0005743mitochondrial inner membraneStat3IDARatPMID:23271731|RGD:8554545
Cellular ComponentGO:0005739mitochondrionStat3IDARatPMID:23895834|RGD:8694316
Cellular ComponentGO:0005654nucleoplasmSTAT3IDAHumanGO_REF:0000052
Cellular ComponentGO:0005634nucleusSTAT3IDAHumanPMID:12743296
Cellular ComponentGO:0005634nucleusSTAT3IDAHumanPMID:17344214
Cellular ComponentGO:0005634nucleusSTAT3IDAHumanPMID:12444102
Cellular ComponentGO:0005634nucleusSTAT3IDAHumanPMID:17324931
Cellular ComponentGO:0005634nucleusSTAT3IDAHumanPMID:17360477
Cellular ComponentGO:0005634nucleusSTAT3IDAHumanPMID:18234692
Cellular ComponentGO:0005634nucleusSTAT3IDAHumanPMID:22783022
Cellular ComponentGO:0005634nucleusSTAT3IDAHumanPMID:24846175
Cellular ComponentGO:0005634nucleusSTAT3IDAHumanPMID:28065600
Cellular ComponentGO:0005634nucleusSTAT3IDAHumanPMID:31899195
Cellular ComponentGO:0005634nucleusStat3IDAMouseMGI:MGI:4889014|PMID:21234744
Cellular ComponentGO:0005634nucleusStat3IDAMouseMGI:MGI:5284803|PMID:15156153
Cellular ComponentGO:0005634nucleusStat3IDAMousePMID:27830702
Cellular ComponentGO:0005634nucleusStat3IDAMousePMID:16801560
Cellular ComponentGO:0005634nucleusStat3IDAMousePMID:19796622
Cellular ComponentGO:0005634nucleusStat3IDAMousePMID:15096606
Cellular ComponentGO:0005634nucleusStat3IDAMousePMID:12826573
Cellular ComponentGO:0005634nucleusStat3IDAMousePMID:15659653
Cellular ComponentGO:0005634nucleusStat3IDAMousePMID:22891351
Cellular ComponentGO:0005634nucleusStat3IDAMousePMID:12634107
Cellular ComponentGO:0005634nucleusStat3IDAMousePMID:24211183
Cellular ComponentGO:0005634nucleusStat3IDARatPMID:16648019|RGD:2298581
Cellular ComponentGO:0005634nucleusStat3IDARatPMID:18230613|RGD:2291921
Cellular ComponentGO:0005886plasma membraneStat3IDAMousePMID:12826573
Cellular ComponentGO:0014069postsynaptic densityStat3IDARatPMID:10891587|RGD:13702226
Cellular ComponentGO:0090575RNA polymerase II transcription regulator complexSTAT3IPIHumanPMID:17676033
Cellular ComponentGO:0090575RNA polymerase II transcription regulator complexSTAT3IPIHumanPMID:8662591
Cellular ComponentGO:0090575RNA polymerase II transcription regulator complexSTAT3IMPHumanPMID:16946298
Cellular ComponentGO:0098685Schaffer collateral - CA1 synapseStat3EXPRatPMID:22284190|RGD:13702421
Cellular ComponentGO:0098685Schaffer collateral - CA1 synapseStat3IDARatPMID:22284190|RGD:13702421
Cellular ComponentGO:0098685Schaffer collateral - CA1 synapseStat3IMPRatPMID:22284190|RGD:13702421
Cellular ComponentGO:0005667transcription regulator complexSTAT3IDAHumanPMID:24429361
Cellular ComponentGO:0005667transcription regulator complexStat3IDAMousePMID:19911006
Biological ProcessGO:0006953acute-phase responseStat3IEPRatPMID:8530402|RGD:730023
Biological ProcessGO:0007568agingStat3IEPRatPMID:21633715|RGD:7247626
Biological ProcessGO:0048708astrocyte differentiationStat3IMPMouseMGI:MGI:5284803|PMID:15156153
Biological ProcessGO:0003401axis elongationstat3IMPZFIN:ZDB-GENO-170502-7ZfishPMID:28222105
Biological ProcessGO:0003401axis elongationstat3IMPZFIN:ZDB-GENO-170502-9ZfishPMID:28222105
Biological ProcessGO:0061026cardiac muscle tissue regenerationstat3IMPZFIN:ZDB-GENO-131101-5ZfishPMID:23901114
Biological ProcessGO:0030154cell differentiationSTAT3IDAHumanPMID:28781374
Biological ProcessGO:0042074cell migration involved in gastrulationstat3IMPZfishPMID:15129296
Biological ProcessGO:0008283cell population proliferationStat3IDAMousePMID:15659653
Biological ProcessGO:0008283cell population proliferationstat3IMPZFIN:ZDB-GENO-190515-8ZfishPMID:29690953
Biological ProcessGO:0071345cellular response to cytokine stimulusStat3IDARatPMID:19414010|RGD:10402041
Biological ProcessGO:0032870cellular response to hormone stimulusSTAT3IDAHumanPMID:12552091
Biological ProcessGO:0097398cellular response to interleukin-17Stat3IDAMousePMID:30294880
Biological ProcessGO:0044320cellular response to leptin stimulusSTAT3IDAHumanPMID:17344214
Biological ProcessGO:0071407cellular response to organic cyclic compoundStat3IDARatPMID:19414010|RGD:10402041
Biological ProcessGO:0042755eating behaviorStat3IMPMGI:MGI:2176173,MGI:MGI:2451328MousePMID:15070774
Biological ProcessGO:0097009energy homeostasisStat3IMPMouseMGI:MGI:2652302|PMID:12594516
Biological ProcessGO:0001837epithelial to mesenchymal transitionstat3IMPZfishPMID:15129296
Biological ProcessGO:0030010establishment of cell polaritystat3IMPZfishPMID:15452141
Biological ProcessGO:0001736establishment of planar polaritystat3IMPZfishPMID:15452141
Biological ProcessGO:0010467gene expressionStat3IMPMGI:MGI:1926816MousePMID:23453632
Biological ProcessGO:0042593glucose homeostasisStat3IMPMouseMGI:MGI:2652302|PMID:12594516
Biological ProcessGO:0042593glucose homeostasisStat3IMPMGI:MGI:2176173,MGI:MGI:2451328MousePMID:15070774
Biological ProcessGO:0060396growth hormone receptor signaling pathwaySTAT3IDAHumanPMID:10925297
Biological ProcessGO:0060397growth hormone receptor signaling pathway via JAK-STATSTAT3IDAHumanPMID:12552091
Biological ProcessGO:0060397growth hormone receptor signaling pathway via JAK-STATStat3IDAMouseMGI:MGI:3828422|PMID:8923468
Biological ProcessGO:0070365hepatocyte differentiationstat3IMPZFIN:ZDB-GENO-190515-8ZfishPMID:29690953
Biological ProcessGO:0006954inflammatory responseStat3IMPMouseMGI:MGI:5825383|PMID:28065600
Biological ProcessGO:0006954inflammatory responseStat3IMPMGI:MGI:1926816MousePMID:23453632
Biological ProcessGO:0060119inner ear receptor cell developmentstat3IMPZFIN:ZDB-MRPHLNO-051004-1ZfishPMID:22855815
Biological ProcessGO:0038154interleukin-11-mediated signaling pathwaySTAT3IDAHumanPMID:28781374
Biological ProcessGO:0035723interleukin-15-mediated signaling pathwaySTAT3IDAHumanPMID:7568001
Biological ProcessGO:0038110interleukin-2-mediated signaling pathwaySTAT3IDAHumanPMID:7568005
Biological ProcessGO:0070102interleukin-6-mediated signaling pathwaySTAT3IDAHumanPMID:12359225
Biological ProcessGO:0070102interleukin-6-mediated signaling pathwaySTAT3IDAHumanPMID:12552091
Biological ProcessGO:0070102interleukin-6-mediated signaling pathwaySTAT3IMPHumanPMID:16835372
Biological ProcessGO:0070102interleukin-6-mediated signaling pathwaySTAT3IMPHumanPMID:16946298
Biological ProcessGO:0070102interleukin-6-mediated signaling pathwaySTAT3IDAHumanPMID:17324931
Biological ProcessGO:0070102interleukin-6-mediated signaling pathwaySTAT3IDAHumanPMID:24429361
Biological ProcessGO:0038113interleukin-9-mediated signaling pathwaySTAT3IDAHumanPMID:9535918
Biological ProcessGO:0030522intracellular receptor signaling pathwaySTAT3IDAHumanPMID:17324931
Biological ProcessGO:0033210leptin-mediated signaling pathwaySTAT3IDAHumanPMID:17344214
Biological ProcessGO:0033210leptin-mediated signaling pathwayStat3IMPMouseMGI:MGI:2652302|PMID:12594516
Biological ProcessGO:0033210leptin-mediated signaling pathwayStat3IDAMouseMGI:MGI:5700303|PMID:16825198
Biological ProcessGO:0050804modulation of chemical synaptic transmissionStat3EXPRatPMID:22284190|RGD:13702421
Biological ProcessGO:0050804modulation of chemical synaptic transmissionStat3IDARatPMID:22284190|RGD:13702421
Biological ProcessGO:0050804modulation of chemical synaptic transmissionStat3IMPRatPMID:22284190|RGD:13702421
Biological ProcessGO:0008045motor neuron axon guidancestat3IMPZFIN:ZDB-MRPHLNO-061002-1ZfishPMID:16729994
Biological ProcessGO:0042789mRNA transcription by RNA polymerase IIStat3IDAMousePMID:26026268
Biological ProcessGO:0010507negative regulation of autophagySTAT3IDAHumanPMID:26962683
Biological ProcessGO:0008285negative regulation of cell population proliferationStat3IGIMGI:MGI:88190MousePMID:22891351
Biological ProcessGO:0010629negative regulation of gene expressionSTAT3IDAHumanPMID:23820254
Biological ProcessGO:0045820negative regulation of glycolytic processStat3IMPMousePMID:22891351
Biological ProcessGO:0010730negative regulation of hydrogen peroxide biosynthetic processStat3IMPRatPMID:23590160|RGD:8694322
Biological ProcessGO:0050728negative regulation of inflammatory responseStat3IDAMousePMID:28811323
Biological ProcessGO:0106015negative regulation of inflammatory response to woundingStat3IDAMousePMID:27830702
Biological ProcessGO:1901215negative regulation of neuron deathStat3IMPRatPMID:23884942|RGD:8694331
Biological ProcessGO:2001223negative regulation of neuron migrationStat3IGIMGI:MGI:1918021MousePMID:23321696
Biological ProcessGO:2001223negative regulation of neuron migrationStat3IGIMGI:MGI:95789MousePMID:23321696
Biological ProcessGO:2000635negative regulation of primary miRNA processingSTAT3IMPHumanPMID:31507089
Biological ProcessGO:2000737negative regulation of stem cell differentiationStat3IMPMousePMID:25335925
Biological ProcessGO:0014065phosphatidylinositol 3-kinase signalingStat3IDAMousePMID:27830702
Biological ProcessGO:0016310phosphorylationStat3IDAMouseMGI:MGI:5488544|PMID:23401489
Biological ProcessGO:0045766positive regulation of angiogenesisStat3IDAMouseMGI:MGI:6102138|PMID:26505789
Biological ProcessGO:2001171positive regulation of ATP biosynthetic processStat3IMPRatPMID:23590160|RGD:8694322
Biological ProcessGO:0030335positive regulation of cell migrationSTAT3IMPHumanPMID:24846175
Biological ProcessGO:0008284positive regulation of cell population proliferationStat3IMPRatPMID:23608221|RGD:10411899
Biological ProcessGO:1900017positive regulation of cytokine production involved in inflammatory responseSTAT3IGIRNAcentral:URS00004E0808_9606,UniProtKB:P05231HumanPMID:31886314
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionSTAT3IDAHumanPMID:19390056
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionStat3IDAMouseMGI:MGI:5488544|PMID:23401489
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionStat3IMPMouseMGI:MGI:5825383|PMID:28065600
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionStat3IDAMousePMID:11579100
Biological ProcessGO:0045648positive regulation of erythrocyte differentiationSTAT3IMPHumanPMID:28283061
Biological ProcessGO:0010628positive regulation of gene expressionSTAT3IDAHumanPMID:23820254
Biological ProcessGO:0010628positive regulation of gene expressionSTAT3IMPHumanPMID:24255059
Biological ProcessGO:0010628positive regulation of gene expressionStat3IGIUniProtKB:P35951MouseMGI:MGI:5659826|PMID:24255059
Biological ProcessGO:0060252positive regulation of glial cell proliferationstat3IMPZFIN:ZDB-MRPHLNO-100510-3ZfishPMID:19450453
Biological ProcessGO:0060252positive regulation of glial cell proliferationstat3IMPZFIN:ZDB-MRPHLNO-051004-1ZfishPMID:19450453
Biological ProcessGO:1902728positive regulation of growth factor dependent skeletal muscle satellite cell proliferationStat3IMPRatPMID:23869758|RGD:8694323
Biological ProcessGO:0032731positive regulation of interleukin-1 beta productionSTAT3IGIRNAcentral:URS00004E0808_9606,UniProtKB:P05231HumanPMID:31886314
Biological ProcessGO:0032733positive regulation of interleukin-10 productionSTAT3IGIRNAcentral:URS00004E0808_9606,UniProtKB:P05231HumanPMID:31886314
Biological ProcessGO:0032755positive regulation of interleukin-6 productionStat3IGIUniProtKB:P16599RatPMID:29702085|RGD:13800534
Biological ProcessGO:0032757positive regulation of interleukin-8 productionSTAT3IGIRNAcentral:URS00004E0808_9606,UniProtKB:P05231HumanPMID:31886314
Biological ProcessGO:1904685positive regulation of metalloendopeptidase activitySTAT3IGIRNAcentral:URS00003768C5_9606HumanPMID:23820254
Biological ProcessGO:1902895positive regulation of miRNA transcriptionSTAT3IDAHumanPMID:19390056
Biological ProcessGO:1902895positive regulation of miRNA transcriptionSTAT3IDAHumanPMID:23820254
Biological ProcessGO:1902895positive regulation of miRNA transcriptionStat3IMPMouseMGI:MGI:5897552|PMID:20546595
Biological ProcessGO:2000637positive regulation of miRNA-mediated gene silencingSTAT3IDAHumanPMID:23820254
Biological ProcessGO:0051092positive regulation of NF-kappaB transcription factor activityStat3IGIUniProtKB:P16599RatPMID:29702085|RGD:13800534
Biological ProcessGO:0045747positive regulation of Notch signaling pathwayStat3IMPMouseMGI:MGI:5284803|PMID:15156153
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IISTAT3IMPHumanPMID:16835372
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IISTAT3IMPHumanPMID:16946298
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IISTAT3IDAHumanPMID:17324931
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IISTAT3IGIUniProtKB:Q61699HumanPMID:19754877
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IISTAT3IGIUniProtKB:P17947HumanPMID:24429361
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IISTAT3IGIUniProtKB:P49715HumanPMID:24429361
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IISTAT3IDAHumanPMID:27050391
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IISTAT3IGIRNAcentral:URS00004E0808_9606HumanPMID:31886314
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IISTAT3IGIRNAcentral:URS00004E0808_9606,UniProtKB:P05231HumanPMID:31886314
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIStat3IMPMousePMID:30224457
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIStat3IDAMousePMID:24843164
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIStat3IDAMousePMID:15096606
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIStat3IDAMousePMID:15659653
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIStat3IGIMGI:MGI:1933533MousePMID:20530874
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIStat3IDAMousePMID:19666510
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIStat3IGIMGI:MGI:96787MousePMID:16801560
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionSTAT3IGIRNAcentral:URS00004E0808_9606,UniProtKB:P05231HumanPMID:31886314
Biological ProcessGO:1905564positive regulation of vascular endothelial cell proliferationStat3IDAMouseMGI:MGI:6102138|PMID:26505789
Biological ProcessGO:0035677posterior lateral line neuromast hair cell developmentstat3IMPZFIN:ZDB-MRPHLNO-051004-1ZfishPMID:22855815
Biological ProcessGO:0099527postsynapse to nucleus signaling pathwayStat3IDARatPMID:22284190|RGD:13702421
Biological ProcessGO:0099527postsynapse to nucleus signaling pathwayStat3IEPRatPMID:22284190|RGD:13702421
Biological ProcessGO:0006606protein import into nucleusSTAT3IDAHumanPMID:18234692
Biological ProcessGO:0060019radial glial cell differentiationStat3IMPMouseMGI:MGI:5284803|PMID:15156153
Biological ProcessGO:0007259receptor signaling pathway via JAK-STATSTAT3IDAHumanPMID:8272873
Biological ProcessGO:0007259receptor signaling pathway via JAK-STATstat3IMPZFIN:ZDB-GENO-131101-5ZfishPMID:23901114
Biological ProcessGO:0031099regenerationstat3IGIZFIN:ZDB-GENE-030131-7349ZfishPMID:22855815
Biological ProcessGO:0051726regulation of cell cycleSTAT3IDAHumanPMID:17344214
Biological ProcessGO:0051726regulation of cell cycleStat3IDAMouseMGI:MGI:5700303|PMID:16825198
Biological ProcessGO:0042127regulation of cell population proliferationstat3IMPZFIN:ZDB-GENO-170502-9ZfishPMID:28222105
Biological ProcessGO:0042127regulation of cell population proliferationstat3IMPZFIN:ZDB-GENO-170502-7ZfishPMID:28222105
Biological ProcessGO:0008360regulation of cell shapestat3IMPZFIN:ZDB-GENO-170502-9ZfishPMID:28222105
Biological ProcessGO:0008360regulation of cell shapestat3IMPZFIN:ZDB-GENO-170502-7ZfishPMID:28222105
Biological ProcessGO:0008361regulation of cell sizestat3IMPZFIN:ZDB-GENO-170502-7ZfishPMID:28222105
Biological ProcessGO:0008361regulation of cell sizestat3IMPZFIN:ZDB-GENO-170502-9ZfishPMID:28222105
Biological ProcessGO:1900037regulation of cellular response to hypoxiaStat3IMPRatPMID:19450559|RGD:7242910
Biological ProcessGO:0006355regulation of DNA-templated transcriptionSTAT3IDAHumanPMID:15664994
Biological ProcessGO:0006355regulation of DNA-templated transcriptionSTAT3IDAHumanPMID:17344214
Biological ProcessGO:0060259regulation of feeding behaviorStat3IMPMouseMGI:MGI:2652302|PMID:12594516
Biological ProcessGO:0046902regulation of mitochondrial membrane permeabilityStat3IMPRatPMID:23590160|RGD:8694322
Biological ProcessGO:0040014regulation of multicellular organism growthStat3IMPMGI:MGI:2176173,MGI:MGI:2451328MousePMID:15070774
Biological ProcessGO:0034097response to cytokineStat3IDARatPMID:18270592|RGD:2291919
Biological ProcessGO:0032355response to estradiolSTAT3IDAHumanPMID:12552091
Biological ProcessGO:0032355response to estradiolStat3IEPRatPMID:17916759|RGD:2291922
Biological ProcessGO:0045471response to ethanolStat3IEPRatPMID:17916759|RGD:2291922
Biological ProcessGO:0044321response to leptinSTAT3IDAHumanPMID:17344214
Biological ProcessGO:0044321response to leptinStat3IDAMouseMGI:MGI:5700303|PMID:16825198
Biological ProcessGO:0044321response to leptinStat3IMPMouseMGI:MGI:2652302|PMID:12594516
Biological ProcessGO:0014070response to organic cyclic compoundStat3IEPRatPMID:18339648|RGD:2291918
Biological ProcessGO:0010033response to organic substanceStat3IEPRatPMID:17916759|RGD:2291922
Biological ProcessGO:0043434response to peptide hormoneStat3IEPRatPMID:17911393|RGD:2291923
Biological ProcessGO:0009410response to xenobiotic stimulusStat3IEPRatPMID:18031608|RGD:2291896
Biological ProcessGO:0060042retina morphogenesis in camera-type eyestat3IMPZFIN:ZDB-MRPHLNO-100510-3ZfishPMID:23300608
Biological ProcessGO:0060221retinal rod cell differentiationStat3IMPMousePMID:15207851
Biological ProcessGO:0019953sexual reproductionStat3IMPMGI:MGI:2176173,MGI:MGI:2451328MousePMID:15070774
Biological ProcessGO:0001501skeletal system developmentstat3IMPZFIN:ZDB-GENO-170502-8ZfishPMID:28222105
Biological ProcessGO:0001501skeletal system developmentstat3IMPZFIN:ZDB-GENO-170502-7ZfishPMID:28222105
Biological ProcessGO:0001501skeletal system developmentstat3IMPZFIN:ZDB-GENO-170502-6ZfishPMID:28222105
Biological ProcessGO:0035019somatic stem cell population maintenanceStat3IMPMousePMID:20720539
Biological ProcessGO:0072540T-helper 17 cell lineage commitmentStat3IMPMouseMGI:MGI:5825383|PMID:28065600
Biological ProcessGO:0072538T-helper 17 type immune responseSTAT3IDAHumanPMID:31899195
Biological ProcessGO:0001659temperature homeostasisStat3IMPMGI:MGI:2176173,MGI:MGI:2451328MousePMID:15070774
Biological ProcessGO:0006366transcription by RNA polymerase IIStat3IDAMousePMID:11579100
Biological ProcessGO:0006366transcription by RNA polymerase IIStat3IGIMGI:MGI:96787MousePMID:16801560
Biological ProcessGO:0006366transcription by RNA polymerase IIStat3IGIMGI:MGI:1933533MousePMID:20530874
Biological ProcessGO:0007179transforming growth factor beta receptor signaling pathwaySTAT3IGIUniProtKB:P01137HumanPMID:28467929

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory