Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STC1
  • Mouse genes Stc1
  • Rat genes Stc1
  • Zfish genes stc1,stc1l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	STC1	IPI	UniProtKB:P52823	Human	PMID:26195635
Molecular Function	GO:0005515	protein binding	STC1	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Cellular Component	GO:0016324	apical plasma membrane	Stc1	IDA		Rat	PMID:11702003|RGD:2324701
Cellular Component	GO:0005737	cytoplasm	STC1	IDA		Human	PMID:12663264
Cellular Component	GO:0005737	cytoplasm	Stc1	IDA		Rat	PMID:18534560|RGD:2324696
Cellular Component	GO:0005615	extracellular space	Stc1	IDA		Mouse	PMID:11146507
Cellular Component	GO:0005634	nucleus	STC1	IDA		Human	PMID:12663264
Biological Process	GO:0060348	bone development	STC1	IDA		Human	PMID:16377640
Biological Process	GO:0071320	cellular response to cAMP	Stc1	IEP		Rat	PMID:18187254|RGD:2324697
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	Stc1	IEP		Rat	PMID:18187254|RGD:2324697
Biological Process	GO:0071456	cellular response to hypoxia	Stc1	IEP		Rat	PMID:15485913|RGD:2324700
Biological Process	GO:0035988	chondrocyte proliferation	STC1	IDA		Human	PMID:16377640
Biological Process	GO:0046697	decidualization	Stc1	IEP		Rat	PMID:16735553|RGD:2324698
Biological Process	GO:0007566	embryo implantation	Stc1	IEP		Rat	PMID:16735553|RGD:2324698
Biological Process	GO:0001886	endothelial cell morphogenesis	STC1	IDA		Human	PMID:14500721
Biological Process	GO:0003421	growth plate cartilage axis specification	STC1	IDA		Human	PMID:16377640
Biological Process	GO:0006874	intracellular calcium ion homeostasis	STC1	IDA		Human	PMID:12663264
Biological Process	GO:0006874	intracellular calcium ion homeostasis	STC1	IDA		Human	PMID:8700837
Biological Process	GO:0006874	intracellular calcium ion homeostasis	stc1l	IMP	ZFIN:ZDB-MRPHLNO-090924-1	Zfish	PMID:19073903
Biological Process	GO:0051926	negative regulation of calcium ion transport	STC1	IDA		Human	PMID:8700837
Biological Process	GO:0030336	negative regulation of cell migration	STC1	IDA		Human	PMID:17032941
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	stc1l	IGI	ZFIN:ZDB-GENE-040624-12,ZFIN:ZDB-MRPHLNO-090924-1	Zfish	PMID:19073903
Biological Process	GO:0010596	negative regulation of endothelial cell migration	STC1	IDA		Human	PMID:14500721
Biological Process	GO:0010629	negative regulation of gene expression	stc1l	IGI	ZFIN:ZDB-GENE-060503-425	Zfish	PMID:25561895
Biological Process	GO:0010629	negative regulation of gene expression	stc1l	IGI	ZFIN:ZDB-GENE-040426-1143	Zfish	PMID:25561895
Biological Process	GO:0010629	negative regulation of gene expression	stc1l	IGI	ZFIN:ZDB-GENE-040624-12	Zfish	PMID:25561895
Biological Process	GO:1903403	negative regulation of renal phosphate excretion	STC1	IDA		Human	PMID:8700837
Biological Process	GO:0001503	ossification	Stc1	IDA		Rat	PMID:12933688|RGD:737672
Biological Process	GO:0090280	positive regulation of calcium ion import	STC1	IDA		Human	PMID:17032941
Biological Process	GO:0086004	regulation of cardiac muscle cell contraction	STC1	IDA		Human	PMID:12663264
Biological Process	GO:0044070	regulation of monoatomic anion transport	STC1	IDA		Human	PMID:16377640
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	stc1l	IDA		Zfish	PMID:25561895
Biological Process	GO:0051592	response to calcium ion	stc1l	IMP	ZFIN:ZDB-MRPHLNO-090924-1	Zfish	PMID:19073903
Biological Process	GO:0014070	response to organic cyclic compound	Stc1	IEP		Rat	PMID:17881770|RGD:2316086
Biological Process	GO:0033280	response to vitamin D	Stc1	IEP		Rat	PMID:11702003|RGD:2324701

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern