Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STEAP2
  • Mouse genes Steap2
  • Rat genes Steap2
  • Zfish genes steap2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Steap2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008823	cupric reductase activity	Steap2	IDA		Mouse	PMID:16609065
Molecular Function	GO:0052851	ferric-chelate reductase (NADPH) activity	Steap2	IDA		Mouse	PMID:16609065
Cellular Component	GO:0005829	cytosol	STEAP2	IDA		Human	PMID:12095985
Cellular Component	GO:0005769	early endosome	STEAP2	IDA		Human	PMID:12095985
Cellular Component	GO:0005768	endosome	Steap2	IDA		Mouse	PMID:16609065
Cellular Component	GO:0000139	Golgi membrane	STEAP2	IDA		Human	PMID:12095985
Cellular Component	GO:0005886	plasma membrane	STEAP2	IDA		Human	PMID:12095985
Cellular Component	GO:0005886	plasma membrane	Steap2	IDA		Mouse	PMID:16609065
Cellular Component	GO:0030140	trans-Golgi network transport vesicle	STEAP2	IDA		Human	PMID:12095985
Biological Process	GO:0015677	copper ion import	Steap2	IDA		Mouse	PMID:16609065
Biological Process	GO:0098705	copper ion import across plasma membrane	Steap2	IDA		Mouse	PMID:16609065
Biological Process	GO:0006897	endocytosis	STEAP2	IDA		Human	PMID:12095985
Biological Process	GO:0006893	Golgi to plasma membrane transport	STEAP2	IDA		Human	PMID:12095985
Biological Process	GO:0098706	iron ion import across cell outer membrane	Steap2	IDA		Mouse	PMID:16609065
Biological Process	GO:0098711	iron ion import across plasma membrane	Steap2	IDA		Mouse	PMID:16609065
Biological Process	GO:0045055	regulated exocytosis	STEAP2	IDA		Human	PMID:12095985
Biological Process	GO:0009725	response to hormone	STEAP2	IDA		Human	PMID:12095985

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern