Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CSTA
  • Mouse genes Stfa2
  • Rat genes Stfa2,Stfa3l1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stfa2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004869	cysteine-type endopeptidase inhibitor activity	CSTA	IDA		Human	PMID:3488317
Molecular Function	GO:0004869	cysteine-type endopeptidase inhibitor activity	CSTA	IDA		Human	PMID:6203523
Molecular Function	GO:0004866	endopeptidase inhibitor activity	Stfa2	IDA		Mouse	PMID:16831429
Molecular Function	GO:0002020	protease binding	CSTA	IPI	UniProtKB:P09668	Human	PMID:6203523
Molecular Function	GO:0005515	protein binding	CSTA	IPI	UniProtKB:P00784	Human	PMID:11152132
Molecular Function	GO:0005515	protein binding	CSTA	IPI	UniProtKB:G5E9A7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CSTA	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CSTA	IPI	UniProtKB:P04792	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CSTA	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CSTA	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CSTA	IPI	UniProtKB:Q9Y3C5	Human	PMID:32814053
Cellular Component	GO:0001533	cornified envelope	CSTA	IDA		Human	PMID:10908733
Cellular Component	GO:0005737	cytoplasm	CSTA	IDA		Human	PMID:21944047
Cellular Component	GO:0005829	cytosol	CSTA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005615	extracellular space	CSTA	IDA		Human	PMID:3488317
Cellular Component	GO:0005654	nucleoplasm	CSTA	IDA		Human	GO_REF:0000052
Cellular Component	GO:1904090	peptidase inhibitor complex	CSTA	IPI		Human	PMID:20860624
Biological Process	GO:0098609	cell-cell adhesion	CSTA	IMP		Human	PMID:21944047
Biological Process	GO:0030216	keratinocyte differentiation	CSTA	IDA		Human	PMID:10908733
Biological Process	GO:0010951	negative regulation of endopeptidase activity	Stfa2	IDA		Mouse	PMID:16831429
Biological Process	GO:0010466	negative regulation of peptidase activity	CSTA	IDA		Human	PMID:20860624
Biological Process	GO:0010466	negative regulation of peptidase activity	CSTA	IDA		Human	PMID:6203523
Biological Process	GO:0045861	negative regulation of proteolysis	CSTA	IDA		Human	PMID:3488317
Biological Process	GO:0018149	peptide cross-linking	CSTA	IDA		Human	PMID:10908733

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern