Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STK3
  • Mouse genes Stk3
  • Rat genes Stk3
  • Zfish genes stk3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stk3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	STK3	IDA		Human	PMID:8566796
Molecular Function	GO:0042802	identical protein binding	STK3	IPI	UniProtKB:Q13188	Human	PMID:20562859
Molecular Function	GO:0042802	identical protein binding	STK3	IPI	UniProtKB:Q13188	Human	PMID:23972470
Molecular Function	GO:0000287	magnesium ion binding	STK3	IDA		Human	PMID:8566796
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9NS23-2	Human	PMID:14729613
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H4B6	Human	PMID:16930133
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9NS23-2	Human	PMID:18347058
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q15208	Human	PMID:18362890
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H8S9	Human	PMID:18362890
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P31749	Human	PMID:20086174
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P31749	Human	PMID:20231902
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:O95166	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P60520	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q13043	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q8WWW0	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9BXW4	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9GZQ8	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H0R8	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H4B6	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P50749	Human	PMID:20920251
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q13043	Human	PMID:20920251
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q86WH2	Human	PMID:20920251
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q8WWW0-1	Human	PMID:20920251
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H2L5	Human	PMID:20920251
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H4B6	Human	PMID:20920251
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9NS23-2	Human	PMID:20920251
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P03372	Human	PMID:21104395
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9NS23	Human	PMID:21199877
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q8WWW0	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H4B6	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q13043	Human	PMID:23386615
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P50749	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q13043	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q86WH2	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q8WWW0	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H2L5	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H4B6	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q8WWW0-1	Human	PMID:23972470
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H8S9	Human	PMID:23972470
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P50749	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q13043	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q14BN4	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q7L9L4	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q86WH2	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q8WWW0	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H2L5	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H4B6	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H8S9	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P50749	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q13043	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q86WH2	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q8WWW0	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H2L5	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H4B6	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P04049	Human	PMID:24929361
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P50749	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q13043	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q8WWW0	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H4B6	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P0C1Z6-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P50749	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q13077	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q14BN4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q53SE7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q8IZU0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q99259	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H2L5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:O95835|UniProtKB:Q9H4B6	Human	PMID:28087714
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P27448	Human	PMID:28087714
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q8TDM6	Human	PMID:28087714
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P50749	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H4B6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9NS23-2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:O95166,UniProtKB:Q9BXW4	Human	PMID:31857374
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P0C1Z6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P50749	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q13077	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q7L9L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q86TA1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q8TAD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H2L5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H4B6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9NS23-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:P50749	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q13043	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q14BN4	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q86WH2	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q8WWW0	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q9H4B6	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	STK3	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Stk3	IPI	UniProtKB:E9Q9R9	Mouse	MGI:MGI:5823491|PMID:28087714
Molecular Function	GO:0004672	protein kinase activity	STK3	IDA		Human	PMID:28087714
Molecular Function	GO:0004674	protein serine/threonine kinase activity	STK3	EXP		Human	PMID:11278283
Molecular Function	GO:0004674	protein serine/threonine kinase activity	STK3	EXP		Human	PMID:15109305
Molecular Function	GO:0004674	protein serine/threonine kinase activity	STK3	EXP		Human	PMID:15688006
Molecular Function	GO:0004674	protein serine/threonine kinase activity	STK3	EXP		Human	PMID:16930133
Molecular Function	GO:0004674	protein serine/threonine kinase activity	STK3	IDA		Human	PMID:18328708
Molecular Function	GO:0004674	protein serine/threonine kinase activity	STK3	IDA		Human	PMID:18362890
Molecular Function	GO:0004674	protein serine/threonine kinase activity	STK3	IDA		Human	PMID:19525978
Molecular Function	GO:0004674	protein serine/threonine kinase activity	STK3	IDA		Human	PMID:8566796
Cellular Component	GO:0005737	cytoplasm	STK3	IDA		Human	PMID:19525978
Cellular Component	GO:0005737	cytoplasm	STK3	IDA		Human	PMID:21145499
Cellular Component	GO:0005737	cytoplasm	Stk3	IDA		Mouse	PMID:11805089
Cellular Component	GO:0005634	nucleus	STK3	IDA		Human	PMID:21145499
Cellular Component	GO:0032991	protein-containing complex	STK3	IDA		Human	PMID:19962960
Biological Process	GO:0006915	apoptotic process	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0043010	camera-type eye development	stk3	IMP	ZFIN:ZDB-MRPHLNO-140905-2	Zfish	PMID:24828882
Biological Process	GO:0060070	canonical Wnt signaling pathway	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0060706	cell differentiation involved in embryonic placenta development	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:19786569
Biological Process	GO:0008283	cell population proliferation	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:19786569
Biological Process	GO:0008283	cell population proliferation	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0007417	central nervous system development	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:19786569
Biological Process	GO:0003157	endocardium development	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:19786569
Biological Process	GO:0050673	epithelial cell proliferation	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	Stk3	IGI	MGI:MGI:1928487	Mouse	PMID:20080598
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	Stk3	IGI	MGI:MGI:104798	Mouse	PMID:20080598
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0097284	hepatocyte apoptotic process	Stk3	IGI	MGI:MGI:104798	Mouse	PMID:20080598
Biological Process	GO:0035329	hippo signaling	STK3	IDA		Human	PMID:20412773
Biological Process	GO:0035329	hippo signaling	Stk3	IMP		Mouse	MGI:MGI:4420842|PMID:20080689
Biological Process	GO:0035556	intracellular signal transduction	STK3	IDA		Human	PMID:8566796
Biological Process	GO:0007254	JNK cascade	Stk3	IGI	MGI:MGI:104798	Mouse	PMID:20080598
Biological Process	GO:0007254	JNK cascade	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	STK3	IMP		Human	PMID:20412773
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0008285	negative regulation of cell population proliferation	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:19786569
Biological Process	GO:0008285	negative regulation of cell population proliferation	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0046621	negative regulation of organ growth	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0001841	neural tube formation	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:19786569
Biological Process	GO:0035265	organ growth	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0043065	positive regulation of apoptotic process	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	STK3	IGI	UniProtKB:Q9H4B6	Human	PMID:22292086
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Stk3	IGI	MGI:MGI:1928487	Mouse	PMID:20080598
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Stk3	IGI	MGI:MGI:104798	Mouse	PMID:20080598
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0045600	positive regulation of fat cell differentiation	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:22292086
Biological Process	GO:0046330	positive regulation of JNK cascade	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0046330	positive regulation of JNK cascade	Stk3	IGI	MGI:MGI:104798	Mouse	PMID:20080598
Biological Process	GO:0032092	positive regulation of protein binding	STK3	IDA		Human	PMID:22292086
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	Stk3	IGI	MGI:MGI:104798	Mouse	PMID:20080598
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0060215	primitive hemopoiesis	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:19786569
Biological Process	GO:0006606	protein import into nucleus	STK3	IGI	UniProtKB:Q13043	Human	PMID:16751106
Biological Process	GO:0043491	protein kinase B signaling	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:20080598
Biological Process	GO:0043491	protein kinase B signaling	Stk3	IGI	MGI:MGI:104798	Mouse	PMID:20080598
Biological Process	GO:0006468	protein phosphorylation	STK3	IDA		Human	PMID:19525978
Biological Process	GO:0006468	protein phosphorylation	STK3	IDA		Human	PMID:20086174
Biological Process	GO:0006468	protein phosphorylation	STK3	IDA		Human	PMID:20231902
Biological Process	GO:0006468	protein phosphorylation	STK3	IDA		Human	PMID:8566796
Biological Process	GO:0050821	protein stabilization	STK3	IMP		Human	PMID:22292086
Biological Process	GO:0060800	regulation of cell differentiation involved in embryonic placenta development	Stk3	IGI	MGI:MGI:1929004	Mouse	PMID:24595170
Biological Process	GO:0061912	selective autophagy	STK3	IEP		Human	PMID:31857374
Biological Process	GO:0061912	selective autophagy	STK3	IMP		Human	PMID:31857374
Biological Process	GO:0061912	selective autophagy	STK3	IPI	UniProtKB:O95166,UniProtKB:Q9BXW4	Human	PMID:31857374

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern