Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Stk39

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes STK39
- Mouse genes Stk39
- Rat genes Stk39
- Zfish genes stk39
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stk39

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016301	kinase activity	Stk39	IMP		Mouse	MGI:MGI:6201894\|PMID:16530727
Molecular Function	GO:0016301	kinase activity	Stk39	IMP		Rat	PMID:12740379\|RGD:11535106
Molecular Function	GO:0005515	protein binding	STK39	IPI	UniProtKB:P55011	Human	PMID:16669787
Molecular Function	GO:0005515	protein binding	STK39	IPI	UniProtKB:Q9Y376	Human	PMID:21423148
Molecular Function	GO:0005515	protein binding	STK39	IPI	UniProtKB:Q9H2X9-1	Human	PMID:24393035
Molecular Function	GO:0005515	protein binding	STK39	IPI	UniProtKB:Q9UHW9-4	Human	PMID:24393035
Molecular Function	GO:0005515	protein binding	STK39	IPI	UniProtKB:Q9UP95	Human	PMID:24393035
Molecular Function	GO:0005515	protein binding	STK39	IPI	UniProtKB:Q9Y666	Human	PMID:24393035
Molecular Function	GO:0005515	protein binding	Stk39	IPI	UniProtKB:P47811\|UniProtKB:P55012	Mouse	MGI:MGI:3807765\|PMID:14563843
Molecular Function	GO:0005515	protein binding	Stk39	IPI	UniProtKB:Q924N4	Mouse	MGI:MGI:6221361\|PMID:27782176
Molecular Function	GO:0005515	protein binding	Stk39	IPI	UniProtKB:Q969Z4	Mouse	MGI:MGI:6201894\|PMID:16530727
Molecular Function	GO:0005515	protein binding	Stk39	IPI	PR:P55014	Mouse	PMID:12386165
Molecular Function	GO:0005515	protein binding	Stk39	IPI	UniProtKB:P55011	Rat	PMID:12740379\|RGD:11535106
Molecular Function	GO:0019901	protein kinase binding	Stk39	IPI	RGD:621141	Rat	PMID:16083423\|RGD:1624357
Molecular Function	GO:0004674	protein serine/threonine kinase activity	STK39	IMP		Human	PMID:10980603
Molecular Function	GO:0004674	protein serine/threonine kinase activity	STK39	IMP		Human	PMID:16669787
Molecular Function	GO:0004674	protein serine/threonine kinase activity	STK39	IDA		Human	PMID:24393035
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Stk39	IGI	UniProtKB:Q6P9R2	Mouse	MGI:MGI:5574433\|PMID:24393035
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Stk39	IMP		Mouse	MGI:MGI:6221361\|PMID:27782176
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Stk39	IDA		Rat	PMID:10980603\|RGD:727300
Cellular Component	GO:0016324	apical plasma membrane	Stk39	IDA		Mouse	PMID:31736353
Cellular Component	GO:0016324	apical plasma membrane	Stk39	IDA		Mouse	PMID:12386165
Cellular Component	GO:0016323	basolateral plasma membrane	Stk39	IDA		Mouse	PMID:12386165
Cellular Component	GO:0044297	cell body	Stk39	IDA		Mouse	PMID:31736353
Cellular Component	GO:0005938	cell cortex	Stk39	IDA		Rat	PMID:25515571\|RGD:11535087
Cellular Component	GO:0005737	cytoplasm	Stk39	IDA		Rat	PMID:9675032\|RGD:730130
Cellular Component	GO:0005856	cytoskeleton	Stk39	IDA		Rat	PMID:9675032\|RGD:730130
Cellular Component	GO:0005829	cytosol	STK39	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	STK39	IMP		Human	PMID:10980603
Cellular Component	GO:0005829	cytosol	Stk39	IMP		Rat	PMID:10980603\|RGD:727300
Cellular Component	GO:0005829	cytosol	Stk39	IDA		Rat	PMID:25515571\|RGD:11535087
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	STK39	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Stk39	IDA		Mouse	PMID:12386165
Cellular Component	GO:0005654	nucleoplasm	STK39	IDA		Human	GO_REF:0000052
Biological Process	GO:0071476	cellular hypotonic response	STK39	IDA		Human	PMID:24393035
Biological Process	GO:0071476	cellular hypotonic response	Stk39	IGI	UniProtKB:Q6P9R2	Mouse	MGI:MGI:5574433\|PMID:24393035
Biological Process	GO:1990869	cellular response to chemokine	STK39	IMP		Human	PMID:27400149
Biological Process	GO:0035865	cellular response to potassium ion	Stk39	IDA		Mouse	PMID:31736353
Biological Process	GO:0038146	chemokine (C-X-C motif) ligand 12 signaling pathway	STK39	IMP		Human	PMID:27400149
Biological Process	GO:0006954	inflammatory response	Stk39	IMP	MGI:MGI:4838422	Mouse	PMID:31786261
Biological Process	GO:0030644	intracellular chloride ion homeostasis	Stk39	IGI	MGI:MGI:2442092	Mouse	PMID:29459793
Biological Process	GO:0035556	intracellular signal transduction	STK39	IDA		Human	PMID:24393035
Biological Process	GO:0035556	intracellular signal transduction	Stk39	IGI	UniProtKB:Q6P9R2	Mouse	MGI:MGI:5574433\|PMID:24393035
Biological Process	GO:0042116	macrophage activation	Stk39	IMP	MGI:MGI:4838422	Mouse	PMID:31786261
Biological Process	GO:0036438	maintenance of lens transparency	Stk39	IMP		Mouse	MGI:MGI:5766617\|PMID:25515571
Biological Process	GO:0050801	monoatomic ion homeostasis	Stk39	IMP	MGI:MGI:3851398	Mouse	PMID:21907141
Biological Process	GO:1905408	negative regulation of creatine transmembrane transporter activity	STK39	IDA		Human	PMID:25531585
Biological Process	GO:0090188	negative regulation of pancreatic juice secretion	Stk39	IMP		Mouse	MGI:MGI:5002793\|PMID:21317537
Biological Process	GO:1901380	negative regulation of potassium ion transmembrane transport	STK39	IDA		Human	PMID:24393035
Biological Process	GO:1901380	negative regulation of potassium ion transmembrane transport	Stk39	IGI	UniProtKB:Q6P9R2	Mouse	MGI:MGI:5574433\|PMID:24393035
Biological Process	GO:1901017	negative regulation of potassium ion transmembrane transporter activity	STK39	IDA		Human	PMID:24393035
Biological Process	GO:1901017	negative regulation of potassium ion transmembrane transporter activity	Stk39	IGI	UniProtKB:Q6P9R2	Mouse	MGI:MGI:5574433\|PMID:24393035
Biological Process	GO:2000650	negative regulation of sodium ion transmembrane transporter activity	STK39	IDA		Human	PMID:25531585
Biological Process	GO:0018105	peptidyl-serine phosphorylation	STK39	IMP		Human	PMID:10980603
Biological Process	GO:0018105	peptidyl-serine phosphorylation	STK39	IDA		Human	PMID:24393035
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	STK39	IMP		Human	PMID:10980603
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	STK39	IMP		Human	PMID:16669787
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	STK39	IDA		Human	PMID:24393035
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	Stk39	IMP		Mouse	MGI:MGI:6221361\|PMID:27782176
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	Stk39	IGI	UniProtKB:Q6P9R2	Mouse	MGI:MGI:5574433\|PMID:24393035
Biological Process	GO:0032414	positive regulation of ion transmembrane transporter activity	Stk39	IMP		Rat	PMID:12740379\|RGD:11535106
Biological Process	GO:1900745	positive regulation of p38MAPK cascade	STK39	IMP		Human	PMID:10980603
Biological Process	GO:1900745	positive regulation of p38MAPK cascade	Stk39	IMP		Rat	PMID:10980603\|RGD:727300
Biological Process	GO:0043268	positive regulation of potassium ion transport	Stk39	IMP		Rat	PMID:19307180\|RGD:2314540
Biological Process	GO:0010820	positive regulation of T cell chemotaxis	STK39	IMP		Human	PMID:27400149
Biological Process	GO:0046777	protein autophosphorylation	STK39	IMP		Human	PMID:10980603
Biological Process	GO:0046777	protein autophosphorylation	Stk39	IMP		Mouse	MGI:MGI:6201894\|PMID:16530727
Biological Process	GO:0046777	protein autophosphorylation	Stk39	IMP		Rat	PMID:10980603\|RGD:727300
Biological Process	GO:0046777	protein autophosphorylation	Stk39	IMP		Rat	PMID:12740379\|RGD:11535106
Biological Process	GO:0006468	protein phosphorylation	Stk39	IMP		Mouse	MGI:MGI:6201894\|PMID:16530727
Biological Process	GO:0006468	protein phosphorylation	Stk39	IMP	MGI:MGI:5462098	Mouse	PMID:24761002
Biological Process	GO:0006468	protein phosphorylation	Stk39	IMP	MGI:MGI:4838422	Mouse	PMID:31786261
Biological Process	GO:0006468	protein phosphorylation	Stk39	IDA		Rat	PMID:10980603\|RGD:727300
Biological Process	GO:0006468	protein phosphorylation	Stk39	IMP		Rat	PMID:12740379\|RGD:11535106
Biological Process	GO:0008217	regulation of blood pressure	Stk39	IMP	MGI:MGI:3851398	Mouse	PMID:21907141
Biological Process	GO:0050727	regulation of inflammatory response	Stk39	IDA		Mouse	PMID:21705622
Biological Process	GO:1904044	response to aldosterone	Stk39	IGI	MGI:MGI:1917097	Mouse	PMID:24039833
Biological Process	GO:0002021	response to dietary excess	Stk39	IMP	MGI:MGI:5462098	Mouse	PMID:24761002
Biological Process	GO:0007165	signal transduction	STK39	IMP	GO:0004674,GO:0005515,GO:0018107	Human	PMID:16669787
Biological Process	GO:0007165	signal transduction	STK39	IDA		Human	PMID:24393035
Biological Process	GO:0035725	sodium ion transmembrane transport	Stk39	IMP		Mouse	PMID:31736353

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.