Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STX3
  • Mouse genes Stx3
  • Rat genes Stx3
  • Zfish genes stx3a,stx3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stx3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050544	arachidonic acid binding	Stx3	IDA		Rat	PMID:16598260|RGD:8553500
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:O95405	Human	PMID:17693260
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q15833	Human	PMID:18588921
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q12846	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q9H115	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:O00410	Human	PMID:29475951
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q12846	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q9H115	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q12846	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q9H115	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:O00559	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:O14880	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:O15173	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:O75208	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:O95721	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:P11912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:P32856-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:P49447	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q12846	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q13190	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q14802-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q15800	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q16623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q5SR56	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q6ZT21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q7Z7G2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q8N4V1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q8N5M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q96MV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q96TC7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q9GZR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q9H115	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q9H2K0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q9H6H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q9NQG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q9NQQ7-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q9NY72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX3	IPI	UniProtKB:Q9Y320	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Stx3	IPI	PR:O09044	Mouse	PMID:18505797
Molecular Function	GO:0005515	protein binding	Stx3	IPI	PR:Q64324	Mouse	PMID:18535671
Molecular Function	GO:0005515	protein binding	Stx3	IPI	UniProtKB:Q28288	Mouse	PMID:8774707
Molecular Function	GO:0005515	protein binding	Stx3	IPI	PR:P63024	Mouse	PMID:18505797
Molecular Function	GO:0005515	protein binding	Stx3	IPI	PR:P63044	Mouse	PMID:18505797
Molecular Function	GO:0005515	protein binding	Stx3	IPI	PR:Q64324	Mouse	PMID:10469351
Molecular Function	GO:0005515	protein binding	Stx3	IPI	PR:Q64324	Mouse	PMID:18505797
Molecular Function	GO:0005515	protein binding	Stx3	IPI	UniProtKB:P21707	Rat	PMID:10397765|RGD:11535116
Molecular Function	GO:0005515	protein binding	Stx3	IPI	UniProtKB:P50232	Rat	PMID:10397765|RGD:11535116
Molecular Function	GO:0005515	protein binding	Stx3	IPI	UniProtKB:P60881	Rat	PMID:16598260|RGD:8553500
Molecular Function	GO:0005515	protein binding	Stx3	IPI	UniProtKB:P61765	Rat	PMID:17442889|RGD:2312426
Molecular Function	GO:0005484	SNAP receptor activity	Stx3	IDA		Rat	PMID:19109692|RGD:2306549
Cellular Component	GO:0016324	apical plasma membrane	STX3	IDA		Human	PMID:16339081
Cellular Component	GO:0016324	apical plasma membrane	Stx3	IDA		Mouse	PMID:18505797
Cellular Component	GO:0016324	apical plasma membrane	Stx3	IDA		Mouse	PMID:10469351
Cellular Component	GO:0042582	azurophil granule	STX3	IDA		Human	PMID:18588921
Cellular Component	GO:0005911	cell-cell junction	STX3	IDA		Human	PMID:15576373
Cellular Component	GO:0030425	dendrite	Stx3	IDA		Mouse	PMID:23395379
Cellular Component	GO:0070062	extracellular exosome	STX3	HDA		Human	PMID:11487543
Cellular Component	GO:0070062	extracellular exosome	STX3	HDA		Human	PMID:19056867
Cellular Component	GO:0098978	glutamatergic synapse	Stx3	IDA		Mouse	PMID:23395379
Cellular Component	GO:0098978	glutamatergic synapse	Stx3	IEP		Mouse	PMID:23395379
Cellular Component	GO:0098978	glutamatergic synapse	Stx3	IMP		Mouse	PMID:23395379
Cellular Component	GO:0098978	glutamatergic synapse	Stx3	IPI		Mouse	PMID:23395379
Cellular Component	GO:0098978	glutamatergic synapse	Stx3	EXP		Mouse	PMID:23395379
Cellular Component	GO:0030426	growth cone	Stx3	IDA		Rat	PMID:16598260|RGD:8553500
Cellular Component	GO:0030027	lamellipodium	STX3	IDA		Human	PMID:21720706
Cellular Component	GO:0042470	melanosome	Stx3	IDA		Mouse	PMID:23549422
Cellular Component	GO:0016020	membrane	Stx3	IDA		Mouse	PMID:23395379
Cellular Component	GO:0043005	neuron projection	Stx3	IDA		Rat	PMID:16598260|RGD:8553500
Cellular Component	GO:0001917	photoreceptor inner segment	Stx3	IMP		Mouse	MGI:MGI:7258358|PMID:33974130
Cellular Component	GO:0001750	photoreceptor outer segment	Stx3	IMP		Mouse	MGI:MGI:7258358|PMID:33974130
Cellular Component	GO:0005886	plasma membrane	STX3	IDA		Human	PMID:21720706
Cellular Component	GO:0005886	plasma membrane	Stx3	IDA		Rat	PMID:17442889|RGD:2312426
Cellular Component	GO:0098794	postsynapse	Stx3	IDA		Mouse	PMID:23395379
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Stx3	IPI		Mouse	PMID:23395379
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Stx3	IEP		Mouse	PMID:23395379
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Stx3	IDA		Mouse	PMID:23395379
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Stx3	IMP		Mouse	PMID:23395379
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Stx3	EXP		Mouse	PMID:23395379
Cellular Component	GO:0030141	secretory granule	Stx3	IDA		Mouse	PMID:18321981
Cellular Component	GO:0031201	SNARE complex	Stx3	IDA		Mouse	PMID:18535671
Cellular Component	GO:0031201	SNARE complex	Stx3	IDA		Rat	PMID:19109692|RGD:2306549
Cellular Component	GO:0031201	SNARE complex	Stx3	IDA		Rat	PMID:16598260|RGD:8553500
Cellular Component	GO:0042581	specific granule	STX3	IDA		Human	PMID:18588921
Cellular Component	GO:0042589	zymogen granule membrane	Stx3	IPI	PR:Q64324	Mouse	PMID:18535671
Cellular Component	GO:0042589	zymogen granule membrane	Stx3	IDA		Mouse	PMID:18535671
Biological Process	GO:0098967	exocytic insertion of neurotransmitter receptor to postsynaptic membrane	Stx3	IPI		Mouse	PMID:23395379
Biological Process	GO:0098967	exocytic insertion of neurotransmitter receptor to postsynaptic membrane	Stx3	IDA		Mouse	PMID:23395379
Biological Process	GO:0098967	exocytic insertion of neurotransmitter receptor to postsynaptic membrane	Stx3	IMP		Mouse	PMID:23395379
Biological Process	GO:0098967	exocytic insertion of neurotransmitter receptor to postsynaptic membrane	Stx3	EXP		Mouse	PMID:23395379
Biological Process	GO:0098967	exocytic insertion of neurotransmitter receptor to postsynaptic membrane	Stx3	IEP		Mouse	PMID:23395379
Biological Process	GO:0006887	exocytosis	Stx3	IMP		Mouse	PMID:18505797
Biological Process	GO:0060291	long-term synaptic potentiation	Stx3	IMP		Mouse	PMID:23395379
Biological Process	GO:0061025	membrane fusion	Stx3	IDA		Rat	PMID:19109692|RGD:2306549
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Stx3	IDA		Mouse	PMID:23395379
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Stx3	IMP		Mouse	PMID:23395379
Biological Process	GO:0031175	neuron projection development	Stx3	IDA		Rat	PMID:16598260|RGD:8553500
Biological Process	GO:0090174	organelle membrane fusion	STX3	IMP		Human	PMID:24726755
Biological Process	GO:0045785	positive regulation of cell adhesion	STX3	IMP		Human	PMID:21720706
Biological Process	GO:0008284	positive regulation of cell population proliferation	STX3	IMP		Human	PMID:21720706
Biological Process	GO:0050921	positive regulation of chemotaxis	STX3	IMP		Human	PMID:21720706
Biological Process	GO:2000010	positive regulation of protein localization to cell surface	STX3	IMP		Human	PMID:21720706
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	STX3	IMP		Human	PMID:21720706
Biological Process	GO:0010468	regulation of gene expression	STX3	IDA		Human	PMID:29475951
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Stx3	IDA		Mouse	PMID:23395379
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Stx3	IMP		Mouse	PMID:23395379
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Stx3	IEP		Mouse	PMID:23395379
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Stx3	IPI		Mouse	PMID:23395379
Biological Process	GO:0099003	vesicle-mediated transport in synapse	Stx3	EXP		Mouse	PMID:23395379

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern