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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Stx4a

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stx4a
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q15836HumanPMID:12130530
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:P63027HumanPMID:12855681
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q6ZWJ1HumanPMID:12855681
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O00186HumanPMID:15576373
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O75379HumanPMID:16189514
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:P54920HumanPMID:16189514
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q15836HumanPMID:16189514
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O00161HumanPMID:16677249
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O15400HumanPMID:21516116
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O43752HumanPMID:21516116
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q53TN4HumanPMID:21516116
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O75396HumanPMID:22153078
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O14653HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O14662HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O15155HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O15400HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O43752HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O75379HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O75379-2HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O95183HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:P23763HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:P25788HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:P63027HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q13190HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q13277HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q15836HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q53TN4HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q5SQN1HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q86Y82HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q96F15HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q96IW7HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q9H115HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q9UEU0HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q9UNK0HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:P50402HumanPMID:25910212
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q53TN4HumanPMID:25910212
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O43752HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O75379-2HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q86Y82HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q13277HumanPMID:29892012
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O95183HumanPMID:30833792
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:P54920HumanPMID:30833792
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q13277HumanPMID:31515488
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q86Y82HumanPMID:31515488
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O14653HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O14662-5HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O15155HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O15400HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O43752HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O60499-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O75379HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O75396HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O75558HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O95159HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O95183HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:O95470HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:P23763-3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:P32856-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:P60201-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:P61266HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:P63027HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:P78317HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q13190HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q13277HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q15836HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q16623HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q86W74-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q86Y82HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q8N511HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q8N8B7-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q8TDT2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q969S6HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q96IV6HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q96IW7HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q9H115HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q9NYB9-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q9NZ43HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q9UEU0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q9UNK0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q9Y228HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:Q9Y6X1HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:P0DTC3HumanPMID:33845483
Molecular FunctionGO:0005515protein bindingSTX4IPIUniProtKB:P0DTC3HumanPMID:34706264
Molecular FunctionGO:0005515protein bindingStx4aIPIUniProtKB:P61765|UniProtKB:Q60770-1MouseMGI:MGI:5918742|PMID:21193638
Molecular FunctionGO:0005515protein bindingStx4aIPIUniProtKB:Q155P7MouseMGI:MGI:3814962|PMID:18827011
Molecular FunctionGO:0005515protein bindingStx4aIPIUniProtKB:P70169MouseMGI:MGI:3838942|PMID:19033398
Molecular FunctionGO:0005515protein bindingStx4aIPIUniProtKB:Q60770-1MouseMGI:MGI:6092969|PMID:17517664
Molecular FunctionGO:0005515protein bindingStx4aIPIUniProtKB:Q60770MouseMGI:MGI:4457249|PMID:17548353
Molecular FunctionGO:0005515protein bindingStx4aIPIPR:Q60770MousePMID:19188424
Molecular FunctionGO:0005515protein bindingStx4aIPIUniProtKB:Q8K401MousePMID:12832401
Molecular FunctionGO:0005515protein bindingStx4aIPIPR:P63044MousePMID:19188424
Molecular FunctionGO:0005515protein bindingStx4aIPIPR:Q60770MousePMID:12297296
Molecular FunctionGO:0005515protein bindingStx4aIPIPR:Q60770MousePMID:18535671
Molecular FunctionGO:0005515protein bindingStx4aIPIPR:Q9WV89MousePMID:10394363
Molecular FunctionGO:0005515protein bindingStx4aIPIPR:E9Q9R9MousePMID:17765678
Molecular FunctionGO:0005515protein bindingStx4IPIUniProtKB:P21707RatPMID:10397765|RGD:11535116
Molecular FunctionGO:0005515protein bindingStx4IPIUniProtKB:P50232RatPMID:10397765|RGD:11535116
Molecular FunctionGO:0005515protein bindingStx4IPIRGD:619968RatPMID:14759605|RGD:2306290
Molecular FunctionGO:0005515protein bindingStx4IPIUniProtKB:Q60770RatPMID:19116655|RGD:13825192
Molecular FunctionGO:0005515protein bindingStx4IPIUniProtKB:P63045RatPMID:23380067|RGD:10047320
Molecular FunctionGO:0005515protein bindingStx4IPIUniProtKB:O09044RatPMID:24469400|RGD:10047308
Molecular FunctionGO:0005515protein bindingStx4IPIUniProtKB:P63045RatPMID:24469400|RGD:10047308
Molecular FunctionGO:0005515protein bindingStx4IPIUniProtKB:Q60770RatPMID:24469400|RGD:10047308
Molecular FunctionGO:0031267small GTPase bindingStx4IPIRGD:3529RatPMID:11063739|RGD:2306283
Molecular FunctionGO:0005484SNAP receptor activityStx4IDARatPMID:19109692|RGD:2306549
Molecular FunctionGO:0000149SNARE bindingStx4aIPIUniProtKB:P63044MouseMGI:MGI:4457249|PMID:17548353
Molecular FunctionGO:0000149SNARE bindingStx4IPIRGD:620221RatPMID:10051443|RGD:634161
Molecular FunctionGO:0030507spectrin bindingStx4IPIRGD:621714RatPMID:16870704|RGD:2306291
Molecular FunctionGO:0016230sphingomyelin phosphodiesterase activator activitySTX4IMPHumanPMID:20956541
Cellular ComponentGO:0016324apical plasma membraneStx4IDARatPMID:14759605|RGD:2306290
Cellular ComponentGO:0016323basolateral plasma membraneSTX4IDAHumanPMID:16339081
Cellular ComponentGO:0016323basolateral plasma membraneStx4aIDAMousePMID:18505797
Cellular ComponentGO:0016323basolateral plasma membraneStx4IDARatPMID:14759605|RGD:2306290
Cellular ComponentGO:0009986cell surfaceSTX4IDAHumanPMID:15576373
Cellular ComponentGO:0009986cell surfaceSTX4IDAHumanPMID:20434989
Cellular ComponentGO:0009986cell surfaceStx4aIDAMouseMGI:MGI:5567905|PMID:21151919
Cellular ComponentGO:0005737cytoplasmStx4aIDAMousePMID:12832401
Cellular ComponentGO:0043197dendritic spineSTX4IDAHumanPMID:20434989
Cellular ComponentGO:0005768endosomeSTX4IDAHumanPMID:20956541
Cellular ComponentGO:0070062extracellular exosomeSTX4HDAHumanPMID:20458337
Cellular ComponentGO:0005615extracellular spaceSTX4IDAHumanPMID:22226963
Cellular ComponentGO:0098978glutamatergic synapseSTX4IDAHumanPMID:27662481
Cellular ComponentGO:0098978glutamatergic synapseSTX4IMPHumanPMID:27662481
Cellular ComponentGO:0098978glutamatergic synapseStx4aIDAMousePMID:24895134
Cellular ComponentGO:0098978glutamatergic synapseStx4aIMPMousePMID:24895134
Cellular ComponentGO:0098978glutamatergic synapseStx4IDARatPMID:20434989|RGD:13702188
Cellular ComponentGO:0098978glutamatergic synapseStx4IMPRatPMID:20434989|RGD:13702188
Cellular ComponentGO:0030027lamellipodiumSTX4IDAHumanPMID:21720706
Cellular ComponentGO:0043219lateral loopStx4aIDAMouseMGI:MGI:4441217|PMID:20237282
Cellular ComponentGO:0016020membraneSTX4IDAHumanPMID:7690687
Cellular ComponentGO:0035749myelin sheath adaxonal regionStx4aIDAMouseMGI:MGI:4441217|PMID:20237282
Cellular ComponentGO:0032589neuron projection membraneStx4IDARatPMID:32963038|RGD:127285397
Cellular ComponentGO:0048471perinuclear region of cytoplasmStx4aIDAMouseMGI:MGI:3814962|PMID:18827011
Cellular ComponentGO:0045335phagocytic vesicleStx4aIDAMousePMID:19144319
Cellular ComponentGO:0005886plasma membraneSTX4IDAHumanGO_REF:0000052
Cellular ComponentGO:0005886plasma membraneSTX4IDAHumanPMID:20956541
Cellular ComponentGO:0005886plasma membraneSTX4IDAHumanPMID:21720706
Cellular ComponentGO:0005886plasma membraneStx4aIPIPR:Q60770MousePMID:18535671
Cellular ComponentGO:0005886plasma membraneStx4aIDAMousePMID:12832401
Cellular ComponentGO:0005886plasma membraneStx4aIDAMousePMID:18535671
Cellular ComponentGO:0005886plasma membraneStx4aIDAMousePMID:21828338
Cellular ComponentGO:0005886plasma membraneStx4IDARatPMID:10051443|RGD:634161
Cellular ComponentGO:0005886plasma membraneStx4IDARatPMID:16870704|RGD:2306291
Cellular ComponentGO:0098794postsynapseSTX4IDAHumanPMID:27662481
Cellular ComponentGO:0098794postsynapseSTX4IMPHumanPMID:27662481
Cellular ComponentGO:0098794postsynapseStx4aIMPMousePMID:24895134
Cellular ComponentGO:0098794postsynapseStx4aIDAMousePMID:24895134
Cellular ComponentGO:0045211postsynaptic membraneStx4IDARatPMID:20434989|RGD:13702188
Cellular ComponentGO:0042383sarcolemmaStx4IDARatPMID:12388133|RGD:2306288
Cellular ComponentGO:0098685Schaffer collateral - CA1 synapseStx4IDARatPMID:20434989|RGD:13702188
Cellular ComponentGO:0098685Schaffer collateral - CA1 synapseStx4IMPRatPMID:20434989|RGD:13702188
Cellular ComponentGO:0031201SNARE complexSTX4IDAHumanPMID:12130530
Cellular ComponentGO:0031201SNARE complexSTX4IDAHumanPMID:19546860
Cellular ComponentGO:0031201SNARE complexStx4aIDAMousePMID:18535671
Cellular ComponentGO:0031201SNARE complexStx4IDARatPMID:10051443|RGD:634161
Cellular ComponentGO:0031201SNARE complexStx4IDARatPMID:19109692|RGD:2306549
Cellular ComponentGO:0031201SNARE complexStx4IDARatPMID:14993220|RGD:8553828
Cellular ComponentGO:0036477somatodendritic compartmentSTX4IDAHumanPMID:20434989
Cellular ComponentGO:0042581specific granuleSTX4IDAHumanPMID:18588921
Cellular ComponentGO:0000322storage vacuoleStx4aIDAMousePMID:21828338
Cellular ComponentGO:0045202synapseSTX4IDAHumanPMID:20434989
Cellular ComponentGO:0005802trans-Golgi networkStx4aIDAMouseMGI:MGI:3814962|PMID:18827011
Biological ProcessGO:0034599cellular response to oxidative stressSTX4IDAHumanPMID:22226963
Biological ProcessGO:0071346cellular response to type II interferonStx4aIDAMousePMID:19144319
Biological ProcessGO:1903575cornified envelope assemblySTX4IDAHumanPMID:22226963
Biological ProcessGO:0098967exocytic insertion of neurotransmitter receptor to postsynaptic membraneStx4IDARatPMID:20434989|RGD:13702188
Biological ProcessGO:0098967exocytic insertion of neurotransmitter receptor to postsynaptic membraneStx4IMPRatPMID:20434989|RGD:13702188
Biological ProcessGO:0060291long-term synaptic potentiationSTX4IDAHumanPMID:20434989
Biological ProcessGO:0061025membrane fusionStx4IDARatPMID:19109692|RGD:2306549
Biological ProcessGO:0048284organelle fusionSTX4IDAHumanPMID:20434989
Biological ProcessGO:0043085positive regulation of catalytic activitySTX4IMPHumanPMID:20956541
Biological ProcessGO:0045785positive regulation of cell adhesionSTX4IMPHumanPMID:21720706
Biological ProcessGO:0030335positive regulation of cell migrationSTX4IMPHumanPMID:15351710
Biological ProcessGO:0008284positive regulation of cell population proliferationSTX4IMPHumanPMID:21720706
Biological ProcessGO:0050921positive regulation of chemotaxisSTX4IMPHumanPMID:21720706
Biological ProcessGO:0043311positive regulation of eosinophil degranulationSTX4IMPHumanPMID:16677249
Biological ProcessGO:0002639positive regulation of immunoglobulin productionSTX4IMPHumanPMID:24055037
Biological ProcessGO:0035774positive regulation of insulin secretion involved in cellular response to glucose stimulusSTX4IMPHumanPMID:12855681
Biological ProcessGO:0035774positive regulation of insulin secretion involved in cellular response to glucose stimulusSTX4IDAHumanPMID:24552216
Biological ProcessGO:2000010positive regulation of protein localization to cell surfaceSTX4IMPHumanPMID:21720706
Biological ProcessGO:1903078positive regulation of protein localization to plasma membraneSTX4IMPHumanPMID:15351710
Biological ProcessGO:1903078positive regulation of protein localization to plasma membraneSTX4IMPHumanPMID:20956541
Biological ProcessGO:1903078positive regulation of protein localization to plasma membraneSTX4IMPHumanPMID:21720706
Biological ProcessGO:0034394protein localization to cell surfaceStx4IMPRatPMID:32963038|RGD:127285397
Biological ProcessGO:0065003protein-containing complex assemblyStx4IDARatPMID:10051443|RGD:634161
Biological ProcessGO:0017157regulation of exocytosisSTX4IMPHumanPMID:20434989
Biological ProcessGO:1902041regulation of extrinsic apoptotic signaling pathway via death domain receptorsSTX4IMPHumanPMID:20956541
Biological ProcessGO:0035493SNARE complex assemblyStx4aIDAMouseMGI:MGI:5567905|PMID:21151919
Biological ProcessGO:0016081synaptic vesicle dockingStx4IDARatPMID:7690687|RGD:68313
Biological ProcessGO:0099003vesicle-mediated transport in synapseStx4IDARatPMID:20434989|RGD:13702188
Biological ProcessGO:0099003vesicle-mediated transport in synapseStx4IMPRatPMID:20434989|RGD:13702188

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory