Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STX6
  • Mouse genes Stx6
  • Rat genes Stx6
  • Zfish genes stx6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stx6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q9HD26	Human	PMID:11384996
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q9HD26	Human	PMID:11707463
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:O75379	Human	PMID:19557002
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q9UID3	Human	PMID:20685960
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q12846	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q9H115	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q9P0N8	Human	PMID:23818989
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q9UID3-1	Human	PMID:23932592
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:O14653	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:P25788	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q12846	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q9H115	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:O75379	Human	PMID:25419848
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:O95721	Human	PMID:25419848
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q12846	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:O94812	Human	PMID:28626000
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:P00533	Human	PMID:30662352
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:P27105	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:P32856-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q12846	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q16623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q49AM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q6UW68	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q8IUR7-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q8N4V1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q8N661	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q96KR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q9H2K0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q9H400	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q9NPL8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q9NY72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:Q9P0T7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	STX6	IPI	UniProtKB:O95721	Human	PMID:33422265
Molecular Function	GO:0005515	protein binding	Stx6	IPI	UniProtKB:E1WAC8	Mouse	MGI:MGI:5634883|PMID:22190682
Molecular Function	GO:0005515	protein binding	Stx6	IPI	PR:Q8R307	Mouse	PMID:14668490
Molecular Function	GO:0005515	protein binding	Stx6	IPI	UniProtKB:Q15075	Rat	PMID:10506127|RGD:8553312
Molecular Function	GO:0005515	protein binding	Stx6	IPI	RGD:1311556	Rat	PMID:14668490|RGD:1549677
Molecular Function	GO:0005515	protein binding	Stx6	IPI	UniProtKB:P50232	Rat	PMID:16618809|RGD:11535113
Molecular Function	GO:0005515	protein binding	Stx6	IPI	UniProtKB:A0JNW5	Rat	PMID:20163565|RGD:13514086
Molecular Function	GO:0005515	protein binding	Stx6	IPI	UniProtKB:O08700	Rat	PMID:9243506|RGD:8553703
Molecular Function	GO:0005515	protein binding	Stx6	IPI	UniProtKB:P54921	Rat	PMID:9243506|RGD:8553703
Molecular Function	GO:0019905	syntaxin binding	STX6	IPI	UniProtKB:O14662	Human	PMID:16154903
Molecular Function	GO:0019905	syntaxin binding	STX6	IPI	UniProtKB:O60499	Human	PMID:16154903
Cellular Component	GO:0005829	cytosol	STX6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005769	early endosome	STX6	IDA		Human	PMID:10506127
Cellular Component	GO:0005794	Golgi apparatus	STX6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	STX6	IDA		Human	PMID:19224922
Cellular Component	GO:0005794	Golgi apparatus	STX6	IDA		Human	PMID:23818989
Cellular Component	GO:0005794	Golgi apparatus	Stx6	IDA		Mouse	PMID:15800058
Cellular Component	GO:0005794	Golgi apparatus	Stx6	IDA		Mouse	PMID:22783020
Cellular Component	GO:0005794	Golgi apparatus	Stx6	IDA		Mouse	PMID:23485813
Cellular Component	GO:0005794	Golgi apparatus	Stx6	IDA		Mouse	PMID:14622145
Cellular Component	GO:0005794	Golgi apparatus	Stx6	IDA		Rat	PMID:8663448|RGD:61759
Cellular Component	GO:0016020	membrane	Stx6	IDA		Mouse	PMID:15886206
Cellular Component	GO:0016020	membrane	Stx6	IDA		Rat	PMID:8663448|RGD:61759
Cellular Component	GO:0005654	nucleoplasm	STX6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0048471	perinuclear region of cytoplasm	STX6	IDA		Human	PMID:10506127
Cellular Component	GO:0048471	perinuclear region of cytoplasm	STX6	IDA		Human	PMID:16154903
Cellular Component	GO:0045335	phagocytic vesicle	Stx6	IMP		Mouse	MGI:MGI:5634883|PMID:22190682
Cellular Component	GO:0055037	recycling endosome	Stx6	IDA		Rat	PMID:30962439|RGD:152995575
Cellular Component	GO:0031201	SNARE complex	STX6	IDA		Human	PMID:19620288
Cellular Component	GO:0008021	synaptic vesicle	Stx6	IDA		Rat	PMID:17110340|RGD:12050113
Cellular Component	GO:0030672	synaptic vesicle membrane	Stx6	IDA		Rat	PMID:17004320|RGD:12050136
Cellular Component	GO:0030672	synaptic vesicle membrane	Stx6	EXP		Rat	PMID:17110340|RGD:12050113
Cellular Component	GO:0030672	synaptic vesicle membrane	Stx6	IDA		Rat	PMID:17110340|RGD:12050113
Cellular Component	GO:0043195	terminal bouton	Stx6	HDA		Rat	PMID:24876496|RGD:10047219
Cellular Component	GO:0005802	trans-Golgi network	STX6	IDA		Human	PMID:16154903
Cellular Component	GO:0005802	trans-Golgi network	Stx6	IDA		Mouse	PMID:17003038
Cellular Component	GO:0005802	trans-Golgi network	Stx6	IDA		Mouse	PMID:17003121
Cellular Component	GO:0032588	trans-Golgi network membrane	Stx6	IDA		Mouse	PMID:19338761
Cellular Component	GO:0032588	trans-Golgi network membrane	Stx6	IDA		Rat	PMID:30962439|RGD:152995575
Cellular Component	GO:0032588	trans-Golgi network membrane	Stx6	IDA		Rat	PMID:9243506|RGD:8553703
Biological Process	GO:0032456	endocytic recycling	STX6	IMP		Human	PMID:25799061
Biological Process	GO:0032456	endocytic recycling	STX6	IMP		Human	PMID:23677696
Biological Process	GO:0032456	endocytic recycling	Stx6	IDA		Rat	PMID:30962439|RGD:152995575
Biological Process	GO:0007032	endosome organization	Stx6	IMP		Mouse	PMID:14668490
Biological Process	GO:0032880	regulation of protein localization	STX6	IMP		Human	PMID:16154903
Biological Process	GO:0032880	regulation of protein localization	Stx6	IMP		Mouse	MGI:MGI:5634883|PMID:22190682
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	STX6	IMP		Human	PMID:19224922
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	Stx6	IDA		Rat	PMID:30962439|RGD:152995575
Biological Process	GO:0016189	synaptic vesicle to endosome fusion	Stx6	IDA		Rat	PMID:17004320|RGD:12050136
Biological Process	GO:0016189	synaptic vesicle to endosome fusion	Stx6	IMP		Rat	PMID:17004320|RGD:12050136
Biological Process	GO:0006906	vesicle fusion	STX6	IPI	UniProtKB:Q15075	Human	PMID:10506127
Biological Process	GO:0016192	vesicle-mediated transport	Stx6	IDA		Rat	PMID:8663448|RGD:61759

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern