Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STX7
  • Mouse genes Stx7
  • Rat genes Stx7
  • Zfish genes stx7l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stx7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019869	chloride channel inhibitor activity	STX7	IDA		Human	PMID:18570918
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q9H270	Human	PMID:11382755
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q9P253	Human	PMID:11382755
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q9BV40	Human	PMID:19557002
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q12846	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q12846	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:O14880	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:O15393-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:P32856-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q0VDI3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q12846	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q14973	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q16623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q24JQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q3SXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q53TN4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q5T4F4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q68DC2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q6IN84	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q6UW68	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q7Z5B4-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q7Z5P4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q86VR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q8N112	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q8N5K1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q8N5M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q8NBQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q8NFK1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q8TBP5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q96DZ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q96HE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q96KR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q9GZY8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q9H400	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q9H902	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q9HA82	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q9NR31	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q9NYP7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q9ULD2-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q9Y320	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q9Y680	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX7	IPI	UniProtKB:Q9BV40	Human	PMID:33422265
Molecular Function	GO:0005515	protein binding	Stx7	IPI	UniProtKB:Q9EQJ0	Mouse	MGI:MGI:6716967|PMID:28855648
Molecular Function	GO:0005515	protein binding	Stx7	IPI	PR:O55026	Mouse	PMID:11591653
Molecular Function	GO:0005515	protein binding	Stx7	IPI	PR:Q8R307	Mouse	PMID:14668490
Molecular Function	GO:0005515	protein binding	Stx7	IPI	RGD:1311556	Rat	PMID:14668490|RGD:1549677
Molecular Function	GO:0044877	protein-containing complex binding	Stx7	IDA		Rat	PMID:11786915|RGD:634188
Molecular Function	GO:0005484	SNAP receptor activity	Stx7	IDA		Rat	PMID:15133481|RGD:4892614
Molecular Function	GO:0000149	SNARE binding	STX7	IDA		Human	PMID:24550300
Molecular Function	GO:0000149	SNARE binding	Stx7	IPI	RGD:620421	Rat	PMID:15133481|RGD:4892614
Molecular Function	GO:0000149	SNARE binding	Stx7	IPI	RGD:621558	Rat	PMID:15133481|RGD:4892614
Molecular Function	GO:0019905	syntaxin binding	STX7	IPI	UniProtKB:Q9UNK0	Human	PMID:10564279
Cellular Component	GO:0042582	azurophil granule	STX7	IDA		Human	PMID:20170677
Cellular Component	GO:0005769	early endosome	STX7	IDA		Human	PMID:10564279
Cellular Component	GO:0005769	early endosome	STX7	IDA		Human	PMID:18980942
Cellular Component	GO:0030139	endocytic vesicle	STX7	IDA		Human	PMID:10564279
Cellular Component	GO:0005768	endosome	STX7	IDA		Human	PMID:10564279
Cellular Component	GO:0005768	endosome	Stx7	IDA		Mouse	PMID:19549681
Cellular Component	GO:0005768	endosome	Stx7	IDA		Rat	PMID:11786915|RGD:634188
Cellular Component	GO:0070062	extracellular exosome	STX7	HDA		Human	PMID:20458337
Cellular Component	GO:0001772	immunological synapse	STX7	IDA		Human	PMID:21438968
Cellular Component	GO:0005770	late endosome	STX7	IDA		Human	PMID:18980942
Cellular Component	GO:0005770	late endosome	STX7	IDA		Human	PMID:21438968
Cellular Component	GO:0031902	late endosome membrane	Stx7	IDA		Rat	PMID:15133481|RGD:4892614
Cellular Component	GO:0005765	lysosomal membrane	STX7	HDA		Human	PMID:17897319
Cellular Component	GO:0005765	lysosomal membrane	Stx7	IDA		Rat	PMID:15133481|RGD:4892614
Cellular Component	GO:0005764	lysosome	STX7	IDA		Human	PMID:18980942
Cellular Component	GO:0048471	perinuclear region of cytoplasm	STX7	IDA		Human	PMID:18570918
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Stx7	IDA		Mouse	PMID:19549681
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Stx7	IDA		Mouse	PMID:18321981
Cellular Component	GO:0005886	plasma membrane	STX7	IDA		Human	PMID:18980942
Cellular Component	GO:0005886	plasma membrane	STX7	IDA		Human	PMID:20170677
Cellular Component	GO:0055037	recycling endosome	STX7	IDA		Human	PMID:18570918
Cellular Component	GO:0031201	SNARE complex	Stx7	IDA		Rat	PMID:11786915|RGD:634188
Cellular Component	GO:0031201	SNARE complex	Stx7	IDA		Rat	PMID:15133481|RGD:4892614
Cellular Component	GO:0030672	synaptic vesicle membrane	Stx7	EXP		Rat	PMID:17110340|RGD:12050113
Cellular Component	GO:0030672	synaptic vesicle membrane	Stx7	IDA		Rat	PMID:17110340|RGD:12050113
Cellular Component	GO:0043195	terminal bouton	Stx7	HDA		Rat	PMID:24876496|RGD:10047219
Cellular Component	GO:0070820	tertiary granule	STX7	IDA		Human	PMID:20170677
Cellular Component	GO:0031982	vesicle	STX7	IDA		Human	PMID:18570918
Cellular Component	GO:0031982	vesicle	STX7	IDA		Human	PMID:20170677
Biological Process	GO:0008333	endosome to lysosome transport	Stx7	IDA		Rat	PMID:15133481|RGD:4892614
Biological Process	GO:0070925	organelle assembly	STX7	IDA		Human	PMID:21438968
Biological Process	GO:0051640	organelle localization	STX7	IDA		Human	PMID:21438968
Biological Process	GO:1902685	positive regulation of receptor localization to synapse	STX7	IMP		Human	PMID:21438968
Biological Process	GO:0001916	positive regulation of T cell mediated cytotoxicity	STX7	IMP		Human	PMID:21438968
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	STX7	IDA		Human	PMID:18570918
Biological Process	GO:0006906	vesicle fusion	Stx7	IDA		Rat	PMID:15133481|RGD:4892614
Biological Process	GO:0016192	vesicle-mediated transport	Stx7	IDA		Rat	PMID:15133481|RGD:4892614

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern