Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STX8
  • Mouse genes Stx8
  • Rat genes Stx8
  • Zfish genes stx8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stx8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019869	chloride channel inhibitor activity	STX8	IDA		Human	PMID:18570918
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q9UEU0	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q9UEU0	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q12846	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q9UEU0	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:O95183	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q9UEU0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:O00623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:O14880	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:O15393-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:O15529	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:O15552	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:O95183	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:O95470	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:O95484	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:O95859	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:P07307-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:P08034	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:P11912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:P32856-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:P48165	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:P49675	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:P54219-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q07820	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q12846	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q13190	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q13323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q16558-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q16623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q496F6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q5T7V8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q68D85	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q6P5S7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q6PL24	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q6UW68	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q6ZT21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q7Z7G2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q7Z7N9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q86VR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q86WK6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q8N183	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q8N4V1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q8N5M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q8N661	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q8TBE3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q8TBP5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q8TDV0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q8WWF3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q8WZ55	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q96E29	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q96HJ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q96MG2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q96PE7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q96Q45-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q99735	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q9BPW9-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q9BXK5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q9GZY8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q9H169-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q9HA82	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q9NR31	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q9NY72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q9UEU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q9Y375	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STX8	IPI	UniProtKB:Q9Y680	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Stx8	IPI	UniProtKB:Q9EQJ0	Mouse	MGI:MGI:6716967|PMID:28855648
Molecular Function	GO:0000149	SNARE binding	stx8	IDA		Zfish	PMID:24550300|ZFIN:ZDB-PUB-200522-24
Molecular Function	GO:0019905	syntaxin binding	STX8	IPI	UniProtKB:O15400	Human	PMID:10564279
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Stx8	IPI	UniProtKB:Q3U487	Mouse	MGI:MGI:4821938|PMID:18821010
Cellular Component	GO:0005769	early endosome	STX8	IDA		Human	PMID:10564279
Cellular Component	GO:0005768	endosome	STX8	IDA		Human	PMID:10564279
Cellular Component	GO:0005770	late endosome	STX8	IDA		Human	PMID:10564279
Cellular Component	GO:0031902	late endosome membrane	Stx8	IDA		Rat	PMID:15133481|RGD:4892614
Cellular Component	GO:0005765	lysosomal membrane	Stx8	IDA		Rat	PMID:15133481|RGD:4892614
Cellular Component	GO:0048471	perinuclear region of cytoplasm	STX8	IDA		Human	PMID:18570918
Cellular Component	GO:0045335	phagocytic vesicle	Stx8	IDA		Mouse	PMID:19144319
Cellular Component	GO:0055037	recycling endosome	STX8	IDA		Human	PMID:18570918
Cellular Component	GO:0031201	SNARE complex	Stx8	IDA		Rat	PMID:11786915|RGD:634188
Cellular Component	GO:0031201	SNARE complex	Stx8	IDA		Rat	PMID:15133481|RGD:4892614
Cellular Component	GO:0005802	trans-Golgi network	STX8	IDA		Human	PMID:10564279
Cellular Component	GO:0031982	vesicle	STX8	IDA		Human	PMID:18570918
Biological Process	GO:0071346	cellular response to type II interferon	Stx8	IDA		Mouse	PMID:19144319
Biological Process	GO:0045022	early endosome to late endosome transport	STX8	IDA		Human	PMID:10564279
Biological Process	GO:0008333	endosome to lysosome transport	Stx8	IDA		Rat	PMID:15133481|RGD:4892614
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	STX8	IDA		Human	PMID:18570918
Biological Process	GO:0006906	vesicle fusion	Stx8	IDA		Rat	PMID:15133481|RGD:4892614
Biological Process	GO:0016192	vesicle-mediated transport	Stx8	IDA		Rat	PMID:15133481|RGD:4892614

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern